颅面部骨切开术的若干入路

在切除颅底区域的肿瘤手术中，采用颅面部骨切开术入路，可直接暴露深部区域肿瘤，使肿瘤能被完全切除，避免盲目操作，增加手术的安全性，并有利于防止术后感染、保留术后容貌，有利于术后进一步放射治疗，根据不同区域的肿瘤，采用不同的手术入路。     

慢性缩窄性心包炎3例误诊分析

慢性缩窄性心包炎３例误诊分析威海市立医院（２６４２００）赵培勇张云王海燕慢性缩窄性心包炎临床表现复杂，误诊率较高。我院最近收治３例患者均误诊，误诊时间最长达３０年。现分析如下。因心慌、气短误诊为扩张型心肌病１例。患者男，５８岁。胸闷、气短３０年，曾在...     

10Gyγ线照射后小鼠两相邻肠段运动变化

本文用同时记录两相邻空肠段的收缩活动来观察经10Gyγ线照射后小肠运动的变化,以了解照射后是否出现逆蠕动,以便进一步分析肠套叠形成的原因.结果表明,照射后两相邻肠段出现强度不一的收缩活动,并且可以产生逆蠕动;但是这种逆蠕动发生的机率是不大的.本实验未观察到逆蠕动发生的规律性.因此,逆蠕动的产生可能是照射后发生肠套叠的部分原因.     

用MRI研究腰痛与腰多裂肌萎缩之关系

目的：以MRI方法探讨腰多裂肌萎缩与腰痛的关系。方法：分析36例腰痛患腰多裂肌萎缩的MRI信号改变并与性别、年龄相匹配的40例健康相对照，分析两相关性。结果：腰痛患88．9％有腰多裂肌萎缩，肌萎缩程度与腰痛显相关，且越是急性患，萎缩程度越重。结论：对于腰痛患，当MRI检查椎管无明显异常时，应注意椎旁肌肉有无萎缩。     

腰椎峡部裂的CT诊断

目的：回顾性分析腰椎峡部裂的ＣＴ表现并讨论其诊断与鉴别诊断，材料与方法，２３例患先行腰椎侧位扫描定位图像，采用与椎间盘平行的角度，自病变脊椎的上一椎体下缘边续发描至于下椎体上缘，层厚４或５ｍｍ必要时在峡部行２ｍｍ，层厚扫描，结果；２３例中，累及双侧２１例，单侧２例，发生在Ｌ５１６例，Ｌ４７例，ＣＴ表现为同一脊椎关节突间的低密度裂隙，出瑞椎弓根下缘平面，走行不规则，裂隙可宽可窄，表面不光滑。     

职业性锰暴露工人健康状况调查分析

对１８２名职业性暴露于锰的电焊工人和１５４名无锰及其它重金属暴露史的对照工人进行健康状况调查，发现暴露组神经系统改变发生率为２６．９６，比数比为２．６２，并且锰暴露年数与神经系统改变呈剂量－反应关系。     

共同性斜视术后的回退问题

共同性斜视矫正术后,近期为双眼正位,但时间长后又能出现以下几种变化:①眼位回退到原斜视方向,②眼位向原斜视方向的相反方向移行;③保持双眼正位。如果我们能将引起眼位变化的因素加以分析,以指导我们手术,会提高斜视矫正手术成功率。现我们将我院的48例共同性斜视(共同性外斜30例,共同性内斜18例)矫正术3年后的情况报告如下:对象和方法一、一般资料;本组病例系1987年12月     

Rosiglitazone down-regulates lipopolysaccharide-induced expression of CD40 and intercellular adhesion molecule 1 in rat peritoneal mesothelial cells through a NF-κB dependent mechanism

Objective To investigate the effect and mechanism by which PPARγ ligand, rosiglitasone, regulates the expression of CD40 and intercellular adhesion molecule 1 (ICAM-1) in the rat peritoneal mesothelial cells (RPMCs) induced by lipopolysaccharide (LPS). Methods RPMCs were harvested from Sprague-Dawley rat peritoneal cavity and maintained under defined in vitro conditions. The cells were randomly divided into groups as follows: medium, LPS (5 mg/L), LPS (5 mg/L)+BAY11-7085(5 μmol/L, NF-κB inhibitor), rosiglitazone (10 μmol/L or 20 μmol/L, peroxisome proliferator-activated receptor γ activator), LPS (5 mg/L)+rosiglitazone (10 μmol/L)+GW9662 (3 μmol/L, peroxisome proliferator-aetivatcd receptor γ antagonist), and LPS (5 mg/L)+vehicle (DMSO 0.2 ml/L). The expressions of CD40 and ICAM-1 RNA in RPMCs were examined by RT-PCR after 3 hour treatment, and the protein expressions of CD40, ICAM-1, p-NF-κB p65 and p-IκBα were examined by Western blot or immunofluorescence after 24 hour treatment. Results Following treatment with LPS, both the expressions of CD40 and ICAM-1 protein in RPMCs were up-regulated significantly (P<0.05), and the phosphoralation of p65 was increased greatly (1.10±0.17 vs 0.55±0.06, P<0.05). BAY11-7085 (5 μmol/L) significantly decreased the protein expression of p-p65 (0.22±0.11 vs 1.10±0.17, P<0.01), CD40 (0.34±0.02 vs 0.50±0.06, P<0.05) and ICAM-1 (0.35±0.16 vs 0.74±0.03, P<0.05). Pretreated with rosiglitazone for 3 h then added with LPS for 1 h, the levels of p-p65, CD40 and ICAM-1 in RPMCs were significantly decreased compared with those of LPS group (0.77±0.08 vs 0.90±0.10, P相似文献