The Effects of Electroacupuncture at the Heart Meridian on Myocardial Contractile Function in Rabbits with Myocardial Ischemia

Acute myocardial ischemia was induced by intravenous injection of pituitrin, and electroacupuncture (EA) was applied at the Heart and Lung Meridians (HM and LM), 3 points on each meridian. The changes in the left intraventricular pressure (LVP), the maximum rise rate of intraventricular pressure (LVP dp/dtmax), the area of cardiac force loop (ACFL), and the maximum shortening velocity of myocardial contractile element (Vmax) were observed. As a result, there were significant differences in the improvement of LVP, LVP dp/dtmax, ACFL and Vmax between EA at HM and LM. The regulatory action of EA at HM on the myocardial contractile function was significantly better than that of EA at LM, indicating that HM has a close relationship with the myocardial contractile function.     

糖尿病小鼠淋巴细胞膜脂区流动性和细胞增生反应的变化

淋巴细胞膜脂区流动性是细胞膜的一种动力学性质,它与细胞的多种功能有关。近年来已用细胞膜流动性的变化来探讨疾病病因机理。糖尿病患者淋巴细胞的免疫功能较正常人低,我们认为这与淋巴细胞膜性质有关。本文用荧光探剂1,6-二苯基-1,3,5-已三烯(DPH)嵌入小鼠完整淋巴细胞膜双脂层中,用荧光偏振法测定正常小鼠和阿脲致糖尿病小鼠的淋巴细胞膜脂区流动性;同时用~3H-dT     

针刺对中枢性心血管功能异常的影响及其途径分析

<正> 针刺体表穴位能治疗相应脏腑的疾病,并存在穴位相对特异性,已为临床证实。我们应用家兔在外周静脉注射异丙基肾上腺素和垂体后叶素,分别造成心动过速和心肌缺血的实验病理模型,结果认为“内关”穴对心血管功能异常有调整治疗作用,说明经脉经穴与相应脏腑存在着功能上的联系。为了进一步分析针刺效应的机制,本实验应用电刺激丘脑下部引起的中枢性心血管功能异常,观察针刺是否也有调整作用并分析共可能途径。     

电针经脉对急性心肌缺血家兔心交感神经放电活动的影响

我们过去的工作证明，电排针刺激心经、小肠经可明显改善心功能。本研究根据“经脉所过，主治所及”和“表里相合”的理论，在家兔急性心肌缺血模型上，观察电排针刺激心经“神门”-“通里”段和小肠经“养老”-“支正”段对急性心肌缺血家兔心交感神经放电活动的影响。     

心经经脉与相应脏腑相关的研究——电针心经对家兔心功能、小肠及脑电活动的影响

目的 :了解分别电针心经、肺经循行路线上的 3个测试点以及不电针的对照组对心功能、小肠及脑电活动的影响。方法 :以左心室内压峰值 (LVP)、左心室内压变化上升最大速率(LVPdp/dtmax)、心力环面积 (ACFL)、心肌收缩成分最大缩短速度 (Vmax)、小肠电图及脑电图为指标 ,静脉滴注垂体后叶素造成心肌缺血动物模型进行观察。结果 :电针心经对心功能、小肠及脑电活动的调节作用比电针肺经显著 ,有相对特异性。结论 :心经作为一条经脉 ,与心功能、小肠及脑电活动有密切关系     

心主二经论

目的:提出"心主二经"假说.方法:从中医、针灸古代文献及现代研究成果入手,分析心经、心包经与心脏之间的关系.结果:中医藏象学说、经络学说及现代针灸经络研究成果中蕴含着丰富的"心主二经"的思想和内容.结论:手少阴经和手厥阴经均当为心所主,即心主二经.     

整合蛋白α5、β1亚基在癌症中的表达与细胞分化的关系

目的研究整合蛋白α5和β1亚基在胃癌,结直肠癌,宫颈癌,乳腺癌的表达与肿瘤的分化程度,侵袭转移等生物行为的关系,及四种癌症之间α5和β1亚基表达的相互关系.方法用免疫组织化学ABC法检测20例胃癌,21例结直肠癌,20例宫颈癌,20例乳腺癌石蜡标本α5、β1亚基的表达水平.结果整合蛋白α5和β1亚基在四种肿瘤中的表达水平有一定类似,癌组织较癌旁组织的表达水平低,高中分化肿瘤比低分化肿瘤表达水平高,但下降概率有差异.α5、β1亚基在同种癌症中表达也有差异,β1的表达水平相对较高.结论整合蛋白α5和β1亚基在癌旁组织中的表达明显高于癌组织,并且与分化程度有关,与转移的关系比较复杂有待进一步研究,α5、β1亚基在四种癌症中的表达有一致性,但也有差异.不同种类亚基在癌症中的表达有差异.     

EXPERIMENTAL RESEARCH ON TREATMENT OF HYPERTENSION WITH ACUPUNCTURE

The effects of acupuncture on blood pressure,microcirculation of bulbar conjunctiva andhemorheology in spontaneous hypertensive rats (SHRs) were observed.The mechanism ofacupuncture to lower blood pressure is discussed from the viewpoint of microcirculation andhemorheology.SHRs and Wistar rats of both sexes weighing about 250g were divided into three groups:1.Acupuncture group of 15 SHRs,in which Quchi (LI 11) and Taichong (Liv 3),Hegu (Li 4)and Zusanli (St 36) were selected and punctured twice a day with the needle retained for 15minutes and the reducing method by twisting and twirling the needle used,15 days constituting a course;2.Control group of 10 SHRs;3.Control group of 10 normal Wistar rats.All rats in groups 2 and 3 were treated in the same way as in Group 1 except for theacupuncture.It was found that the morphology and blood flow of bulbar conjunctiva microcirculation inSHRs were obviously abnormal:the capillaries with blood flow were reduced in number,thearterioles were spasmodic and of smaller diameter,the venules were dilated due to bloodstasis which showed a slow granular flow of blood,the blood viscosity was increased,hematocrit increased,and the time for RBC electrophoresis prolonged.The blood was in astate of high viscosity,high concentration and high aggregation.After acupuncture treat-ment the blood pressure not only fell,but the morphology and blood flow of bulbarconjunctiva microcirculation and the hemorheology of SHRs all improved remarkably.The results suggest that abnormal microcirculation and changes in hemorheology can in-crease the peripheral resistance leading to high blood pressure;and the mechanism ofacupuncture in lowering blood pressure is obviously closely related to the improvement ofmicrocirculation,correction of high viscosity,high concentration and high aggregation ofblood,decrease of peripheral resistance and a balanced hemodynamics.