Congratulation on World Journal of Gastroenterology

Dear Professor Lian-Sheng Ma, Professor Michael Hobsley and I have greatly enjoyed reading the account of all you have done towards the development of "The World Journal of Gastroenterology", as described in the article by Zhen-Xi Li in the November 21st. Issue of the Journal.     

后路脊椎V型截骨术治疗创伤性脊柱后凸畸形

目的总结应用椎弓根钉-棒系统后路脊椎V型截骨术治疗创伤性脊柱后凸畸形的临床经验、技术要点及效果。方法将创伤性脊柱后凸畸形的病人分为两组，进行对比分析。治疗组：应用椎弓根钉-棒系统后路V型截骨内固定术29例；对照组：应用前路椎体骨折复位内固定融合术26例。结果与对照组相比，治疗组术后畸形复发率显著低于对照组（P〈0．05），断钉、松动等并发症发生率显著低于对照组（P〈0．05），骨折不融合、纠正后凸畸形度数对比无显著性差异（P〉0．05）。结论应用椎弓根钉-棒系统后路V型截骨术治疗的创伤性脊柱后凸畸形可有效防止手术后畸形再发生，矫正后凸畸形彻底、安全、可靠。     

NOTES ON AN ENDEMIC CENTRE OF KALA-AZAR IN THE PROVINCE OF HUPEH, CENTRAL CHINA

While the larger and more important endemic areas of kala-azar are fairly well defined, the actual extent of these areas westwards''and southwards appears to be extremely vague. In a recent article Hoeppli* states "that although kala-azar may exist in West, Central and South China, the important endemic centres so far have all been ~ound north of the Yangtze Valley." The uncertainty of our knowledge of the ex- tent,rbf the fringes of the endemic areas should constitute a challenge to all working in those places to make a determined effort to prove the presence or, if possible, the absence of the disease. In these notes I propose to record experiences gained dunng 1936-37 in the small city of Anlu (old name: Teian-fu) in Hupeh which indicate that in that district the disease occurs with sufficient frequency to constitute an endemic focus of kala-azar in Central China and only a few miles north of the Yangtze Valley. .     

STUDY OF AN OUTBREAK OF SCURVY I. CLINICAL FEATURES

During the fall of 1935, CheeIoo University Medical SchooL accepted responsibility for the medical care of 19,000 refugees from the flooded farming districts of south-western Shantung, They were cared for in Tsinan at govemment expense, in 30 groups or "camps", of from 200 t0 1,400 persons each, and were provided with two meals a day, consisting of steamed bread, made of 4th grade wheat flour and millet flour, a thin millet congee and pieces of salt turnip. Many individuals supplemented this diet from time to time with small quantities of vegetables, such as raw onion, red pepper sauce and boiled caloloage bought from vendors. This was more common in the early fall than later in the winter, when their small private funds had, in many cases, been exhausted. Later in the winter, the ingredients of the bread were changed to include corn meal, 4th class wheat flour and millet flour.     

提示多发性硬化的脱髓鞘性神经病患者初次发作后应用免疫球蛋白静脉注射治疗:一项随机、双盲、安慰剂对照试验

背景:静脉注射免疫球蛋白能减少复发缓解型多发性硬化患者的疾病活动。目的:研究静脉注射免疫球蛋白对初发性脱髓鞘性神经病的治疗效果,评估疾病的复发率,通过脑MRI分析发病后1年内的病变进展情况。方法:对出现神经系统症状6周内的91例患者行随机、安慰剂对照、双盲研究。患者随机分为免疫球蛋白治疗组(负荷剂量2.0g/kg)或安慰剂治疗组(0.4g/kg),每隔6周1次,共治疗1年。每3个月进行1次神经病学检查和临床评估,分别在试验开始和结束时行脑MRI扫描。结果:静脉免疫球蛋白治疗组患者进展为多发性硬化的累积概率明显低于安慰剂对照组犤RR0.36…     

中央静脉阻塞行玻璃体切割术和放射状视神经切开术的视力和黄斑解剖结构变化

背景:中央静脉阻塞(CR VO)是一种常见的视网膜血管异常,是引起视力下降的主要原因,通常被认为是由于筛板区的血管阻塞引起。本研究旨在评价神经放射状切开术(R ON)的潜在优势,明确CRV O患者黄斑厚度和黄斑体积的变化。方法:选择10例CR VO患者进行前瞻性先导研究,术前和术后6个月经糖尿病视网膜病变早期治疗研究量表和相应的Snellen等量视力检查,得出视力(VA)评分。术前和术后2、6、12、24周检查彩色眼底照相、荧光血管造影(FA)和OCT,用O CT评估黄斑厚度和黄斑体积。结果:10例患者中有4例术中可观察到再灌注,8例视力评分提高,中位…     

慢性心力衰竭患者长程服用β受体阻断药将明显提高其左心室射血分数

171例慢性心力衰竭患者，随机分为长程服用美托洛尔或卡维地洛9～12个月的治疗组，以及未用药对照组。遂观察两组心血管功能与预后的差异。     

在美国强化补充叶酸的效果:母体高血清α-甲胎蛋白水平显著减低

目的:1998年,美国实行在面包和谷类食品中强化补充叶酸,以试图降低神经管缺陷的发病率。出生登记处的数据表明,该疾病的发病率比最初的预测值降低了20%。本研究中,通过检测母体高血清α-甲胎蛋白(M SAFP)水平的发生率来验证妊娠中期产前诊断时强化补充叶酸的效果较好。方法:采用中位值倍数(M oM)对在一个大型商业实验室接受母体血清学筛查的61119例孕妇的M SAFP水平进行分类。比较美国1997年强制性补充叶酸前和2000年强制性补充叶酸后两组数据的差异。高M SAFP水平进一步被分为高(2.75～4.00M oM)或非常高(>4.00M oM)。采用χ2检验…     

环孢霉素和强的松依赖型重症肌无力患者应用他克莫司治疗的远期预后

79例环孢霉素和强的松依赖型重症肌无力(M G)患者在胸腺切除术后,给予他克莫司治疗平均2.5±0.8年。除2例患者外,其余患者均停用强的松,停药后,反映疾病严重程度的抗乙酰胆碱抗体和M G评分明显降低,且肌力提高39%。5%患者的病情得到完全平稳的缓解,87.3%的患者表现为药理学缓解。所有患者重新开始日常生活的全部活动。环孢霉素和强的松依赖型重症肌无力患者应用他克莫司治疗的远期预后@Ponseti J.M.$Unit of Myasthenia Gravis, Department of Surgery, Hosp. Gen. Universitari Vall d‘H., Passeig Vall d’Hebron 119129, E-080…