Lugol液染色对食管早期癌和癌前病变的诊断价值

目的 探讨Lugol液染色对食管早期癌和癌前病变的诊断价值。方法 对45例食管黏膜可疑病变经内镜以2％Lugol液喷洒染色，观察黏膜染色情况，并取活检送病理组织学检查。结果 45例食管病变染色后，39例呈浅染色或不染色，其中食管癌8例（食管早期癌5例，进展期癌3例），Barrett食管5例，轻至中度不典型增生1l例。本组Lugol液染色对食管早期癌和癌前病变的检出率达46．7％。结论 内镜下应用Lugol液染色结合活检有助于食管早期癌和癌前病变的诊断，且操作简便，具有重要的临床价值。     

A Five-Step Strategy in Treatment of Diabetes

Diabetes is a metabolic syndrome characterized by hyperglycemia. When it manifests itself mainly in hyperglycemia, hypertension, hyperlipemia, hyperurecemia, and obesity, it is also called Ⅹ syndrome, or insulin-resistance syndrome. Step 1. Identifying t…     

李振华教授治疗崩漏经验

著名中医学家李振华,现为河南中医学院教授、主任医师,中华中医药学会终身理事及河南分会名誉会长。曾任河南中医学院院长、第七届全国人大代表等职。是全国首批名老中医药专家,也是国务院批准享受政府特殊津贴者。老师治学严谨,博学多闻,精研医理,善于辨证,在长期的医疗实践中     

自体输血在出血性手术中的应用

外科手术,特别是出血量较大的急诊手术、术中出血较多的心内直视手术、以及颅脑外科手术等用血量大,一直是医疗中棘手的问题,而随着人们对输血所带来并发症的重视,以及近年来血源不足及合理输血、血液保护等,使得自体输血成为主流。本文就自体输血在临床应用,特别是大出血性手术中的应用价值作一综述。     

Cortical plasticity: effect of high and low intensity conditioning electrical stimulations (100 Hz) on SEPs to painful finger stimulation.

OBJECTIVE: To study the effect of high-frequency (100 Hz) repetitive conditioning electrical stimulation (CES, 10 min) on human somatosensory evoked potentials (SEPs) to evaluate if short-term cortical plasticity could be induced. METHODS: Painful electrical stimulations were applied to thumb (D1) and little finger (D5) fingertips, respectively. The 124-channel EEG was recorded from 10 healthy male volunteers. Peak stages around 34, 45, 212, 331 ms were analyzed with focal maximum amplitude (FA) and area magnitude (AM) of scalp field potential, topography, and equivalent current dipole source localisation, comparing before and after two-level CES (high- vs. low-level) applied to the He-Gu acupoint. RESULTS: After a high-level CES, the positive FA and AM of the current efflux showed a significant increase at the early phase 34 ms, and significantly decreased at 45 ms in D1 SEPs. The negative FA and AM of the current influx were significantly increased at late phase 350 ms of the D5 SEPs. Only 36 ms, the z-axis position of dipole was significantly changed from (x: -15.9 mm, y: 29.6 mm, z: 43.9 mm) to (x: -12.9 mm, y: 29.4mm, z: 51.5mm) for the D5 SEPs. CONCLUSIONS: The high-level CES significantly attenuated the subsequent cortical activation (45 ms peak for D1 stimulation). Both low- and high-level CES significantly enhanced the late activities (226, 350 ms) in D5 stimulation. This may be explained by pain sensation change at the level of subcortical cingulate cortex induced by the site-dependent post-effect of CES. SIGNIFICANCE: This study showed cortical plasticity induced by conditioning somatosensory stimulation.     

经皮激光椎间盘减压术治疗椎间盘源性腰痛

目的探讨经皮激光椎间盘减压术（percutaneous laser disc decompression，PLDD）治疗椎间盘源性腰痛的疗效。方法2002年6月～2004年12月我院对36例椎间盘源性腰痛，采用英国DIOMED公司半导体激光仪，激光功率15W，每个激光脉冲持续1s，间隔1s，照射能量800～1200J。VAS评分评价治疗效果。结果手术时间15～60min，平均30min。32例出现“疼痛复制效应”。36例随访6～36个月，平均11个月，32例有效（术后VAS评分改善≥3分18例，≥分14例），4例无效，有效率88．9％（32／36）。结论PLDD治疗椎间盘源性腰痛安全、有效、微创。     

Efficacy and safety of herbal medicines for idiopathic Parkinson's disease: a systematic review.

The objective of this study is to assess the efficacy and safety of herbal medicines (HMs), as a monotherapy or adjunct therapy, compared to placebo or conventional approaches in the treatment of idiopathic Parkinson's disease (PD). We conducted a systematic review of randomized controlled trials from both conventional and alternative medicine sources. Outcome measures were overall improvement, quality of life, reduction of levodopa dose, and adverse events. Nine studies were included, each testing a different HM. Six of the trials had limited internal validity due to major flaws in design, including the lack of proper randomization; insufficient blinding; unclear inclusive criteria in terms of diagnostic criteria, baseline staging, and duration of disease; lack of proper sample size calculation; and insufficient data analysis. Imbalances in gender and ethnicity among the patients in the included trials were observed. No major adverse events emerged, and no specific pattern was detected from the trials describing such data. In addition to major methodological defects, heterogeneity in (1) HM tested, (2) control treatment, and (3) outcome measure hindered in-depth data analysis and synthesis. Current evidence is insufficient to evaluate the efficacy and safety of various HMs. Further studies with improved trial design and reporting, with assessment on cost-effectiveness, quality of life, and qualitative data are warranted.     

深化工科物理教学改革培养创新型人才

分析近年来国内高校教育形式的变化，肯定扎实学生基础、培养创新型人才的重要性，结合多年来在工科物理教改中的探索经验和初步成果，提出了深化工科物理教学改革、培养创新型人才的思路和实现途径。     

护理本科生创造性思维培训

[目的]对护理本科生实施创造性思维训练,并评估该训练方案的有效性。[方法]对20名护理本科生实施为期3个月的创造性思维培训,并与24名不接受培训者进行对照。采用《创造性思维练习》量表对培训前后学生的创造性思维进行测定。[结果]培训后实验组较对照组的创造性思维总分及流畅性得分有显著提高(P<0.05);变通性和独创性得分无统计学意义(P>0.05)。[结论]创造性思维培训对提高护理本科生创造性思维总体有效,其中对提高创造性思维的流畅性效果显著。     

妇科恶性肿瘤放射治疗反应及并发症处理

放射治疗在杀死肿瘤细胞的同时，对肿瘤周围器官的细胞和组织也有杀伤作用，从而引起近期放疗反应和远期并发症。