运用模糊数学建立全脂乳粉卫生质量评价模型

本文运用模糊数学原理，对东台市１９９３年７月份市面上的全脂乳粉抽查监测结果进行卫生质量综合评价，结果令人满意，从而为乳粉卫生质量评比建立了客观有效的评价模型。     

Modeling two dimensions of patient satisfaction: a panel study.

Measurement of patient satisfaction is an essential part of health outcome assessment. The purpose of this study is (a) to compare the stability of an aggregate summary measure and two separate summary measures of patient satisfaction; and, (b) to examine causal effects between two separate summary measures at two points in time. Data were collected from 1,451 Medicare HMO beneficiaries. In conclusion, (a) separate summary measures are recommended for constructing the measure of patient satisfaction and (b) moderate causal relationships and cross-lagged effects between the patient satisfaction measures of qualify of care and access to care were found.     

Osteoclastogenesis in the nonadherent cell population of human bone marrow is inhibited by rhBMP-2 alone or together with rhVEGF.

During bone development and repair, angiogenesis, osteogenesis, and bone remodeling are closely associated processes that share some common mediators. In the present study nonadherent human bone marrow mononuclear cells under the induction of sRANKL and M-CSF, differentiated into osteoclasts with TRAP-positive staining, VNR expression, and Ca-P resorptive activity. The effects of various combinations of rhBMP-2 (0, 3, 30, and 300 ng/mL) and rhVEGF (0 and 25 ng/mL) on osteoclastogenesis potentials were examined in this experimental system. The percentages of TRAP-positive multiple nucleated cells represent osteoclast differentiation potential, and the percentages of resorptive areas in the Ca-P coated plates resemble osteoclast resorption capability. The presence of rhBMP-2 at 30 and 300 ng/mL showed inhibitory effects on osteoclast differentiation and their resorptive capability in the human osteoclast culture system. rhVEGF (25 ng/mL) enhanced the resorptive function of osteoclast whenever it was used alone or combined with 3 ng/mL rhBMP-2. However, rhVEGF-induced resorptive function was inhibited by 30 ng/mL and 300 ng/mL rhBMP-2 in a dose-dependent manner. Statistical analysis demonstrated that an interactive effect exists between rhBMP-2 and rhVEGF on human osteoclastogenesis. These findings suggested that an interactive regulation may exist between BMPs and VEGF signaling pathways during osteoclastogenesis; exact mechanisms are yet to be elucidated.     

无抽搐电痉挛治疗精神分裂症的疗效观察分析

目的观察无抽搐电痉挛（Modified Electrocnvulsive therapy，MECT）治疗精神分裂症的疗效及给予次数的关系。方法将60例诊断为精神分裂症的住院患者按治疗次数随机分为两组，进行MECT的临床资料总结分析。结果治疗次数≥6次组，显效率为83．3％，次数〈6次组显效率为76．7％，两者显效率无显著性差异（P〉0．05），每组治疗前后BPRS评分有显著差异，但两组间比较无显著差异（P〉0．05），未发现严重不良反应。结论MECF安全性高，有一定疗效，与治疗次数关系不大。     

刺五加对~(60)Co-γ射线照射后小鼠胸腺效应的实验研究

采用180只成年小白鼠(雌雄各半),其中168只经一次总剂量为4Gy的~(60)Co—γ射线照射,造成造血放射损伤,再从其中随机选出56只膜腔注射刺五加注射液作为实验用药组,其余小白鼠随机分为盐水对照组(56只),空白对照组(56只)及正常对照组(12只)。实验结果显示。实验用药组的胸腺细胞超微结构的恢复比同期对照组快,胸腺组织DNA含量比同期对照组高。因此,我们认为刺五加可促进辐射损伤后小白鼠胸腺细胞结构的恢复。     

肋骨骨折与肺挫伤

本文总结48例肋骨骨折合并肺挫伤。其中43例为多根多处肋骨骨折伴肺挫伤．5例为单处骨折伴肺挫伤。临床资料表明多根多处肋骨骨折（连枷胸）的伤员之呼吸窘迫症状并不经常和肋骨骨折数目成正比。连枷胸所见的呼吸窘迫，低氧血症及肺内分流增加。主要是肺挫伤导致的肺实质性损害引起，而非胸壁反常运动造成。早期充分的止痛是有效的治疗方法。     

驼背二种截骨术远期效果对比

作者对６３２例强直性脊柱炎并驼背畸形施行二种脊柱截骨矫治术，对其中１３５例病人进行了６～１０年观察，结果表明：７１例椎弓椎体联合截骨效果较好，驼背复发平均３．２°。而６４例椎板截骨效果略差，驼背平均复发１３．５°。经统计学处理，两者对比有显著的统计学意义（ｐ＜０．０１）。作者认为病变未完全静止，截骨术式的选择，术中身体重心前移未彻底纠正，以及外固定时间过短等是影响远期效果的因素。     

Irreversible drop of systemic vascular resistances in patients implanted with a Jarvik total artificial heart

Maintenance of the body's perfusion by a total artificial heart (TAH) may result in physiological alterations to the circulatory system. Little has been said about modifications to systemic vascular resistances (SVR) during TAH assistance. This paper reports on two patients implanted with a Jarvik - 70 cc TAH, who died after 1 and 3 days, both with an irreversible drop of SVR related to a complete loss of vascular tone but not related to sepsis. Activation of multiple cascades of inflammation, triggered by the extracorporeal circulation (ECC), is maintained during TAH support. Desperately sick patients might not be able to face the vaso-active situations created by the inflammatory response.     

光照黄斑部试验的临床研究─—眼底病患者MPT的改变及其机理的探讨

７９只眼底病患眼的光照黄斑部试验（ＭＰＴ）结果显示：中心性浆液性脉络膜视网膜病变、老年性黄斑变性渗出型和Ｒｉｅｇｅｒ型中心性渗出性脉络膜视网膜病变患眼的光照黄斑恢复时间显著延长，其它黄斑部病变患眼也有不同程度的延长。本文结合眼底荧光血管造影和黄斑视野域值试验对光照黄斑部试验的机理进行了探讨。     

应用低严格度—单引物聚合酶链反应对问号钩体中国参考株的…

Ｇ１、Ｇ２引物是对问号钩体具有特异性引物。分别用Ｇ１或Ｇ２单引物对问号钩体中国参考株进行前４个低严格度循环的ＰＣＲ扩增，扩增带谱显示赖型、犬型、致热型、秋季型、澳洲型、临海型、乌尔夫型、溶血型为一类，而爪哇型、拜伦型、波摩那型、七日热型、巴叶赞型塔拉索夫型、曼耗Ⅱ型是不与以上赖型等血清型本为一类，双曲钩体ａｔｏｃ型及伊利尼细丝体伊利尼型的扩增带谱与问号钩体截然不同。应用苯酚法提取的高纯度钩体ＤＮＡ