全文获取类型
收费全文 | 19550篇 |
免费 | 1116篇 |
国内免费 | 57篇 |
专业分类
耳鼻咽喉 | 283篇 |
儿科学 | 597篇 |
妇产科学 | 579篇 |
基础医学 | 2505篇 |
口腔科学 | 702篇 |
临床医学 | 1603篇 |
内科学 | 4628篇 |
皮肤病学 | 501篇 |
神经病学 | 1478篇 |
特种医学 | 362篇 |
外科学 | 2264篇 |
综合类 | 173篇 |
一般理论 | 4篇 |
预防医学 | 2267篇 |
眼科学 | 282篇 |
药学 | 1314篇 |
中国医学 | 97篇 |
肿瘤学 | 1084篇 |
出版年
2024年 | 23篇 |
2023年 | 168篇 |
2022年 | 211篇 |
2021年 | 456篇 |
2020年 | 353篇 |
2019年 | 555篇 |
2018年 | 787篇 |
2017年 | 501篇 |
2016年 | 499篇 |
2015年 | 538篇 |
2014年 | 622篇 |
2013年 | 883篇 |
2012年 | 1417篇 |
2011年 | 1531篇 |
2010年 | 806篇 |
2009年 | 637篇 |
2008年 | 1265篇 |
2007年 | 1247篇 |
2006年 | 1248篇 |
2005年 | 1181篇 |
2004年 | 1079篇 |
2003年 | 999篇 |
2002年 | 899篇 |
2001年 | 405篇 |
2000年 | 473篇 |
1999年 | 359篇 |
1998年 | 104篇 |
1997年 | 91篇 |
1996年 | 59篇 |
1995年 | 65篇 |
1994年 | 65篇 |
1993年 | 67篇 |
1992年 | 121篇 |
1991年 | 106篇 |
1990年 | 110篇 |
1989年 | 75篇 |
1988年 | 70篇 |
1987年 | 73篇 |
1986年 | 78篇 |
1985年 | 69篇 |
1984年 | 42篇 |
1983年 | 40篇 |
1981年 | 21篇 |
1980年 | 26篇 |
1979年 | 26篇 |
1978年 | 26篇 |
1976年 | 19篇 |
1974年 | 21篇 |
1971年 | 25篇 |
1969年 | 21篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
91.
92.
Helena Sousa Oscar Ribeiro Elísio Costa Roberta Frontini Constana Paúl Leonilde Amado Vasco Miranda Fernando Ribeiro Daniela Figueiredo 《Seminars in dialysis》2021,34(1):66-76
For individuals with end‐stage renal disease (ESRD), the novel coronavirus can present several additional challenges in disease self‐management. This study aimed to explore the impacts of the COVID‐19 pandemic in non‐COVID‐19 patients with ESRD undergoing in‐center hemodialysis (HD). A mixed‐methods study was conducted with a purposive sample recruited from one dialysis unit in Portugal. Quantitative data were collected retrospectively from patients' medical records from February 2020 (T1—before the outbreak) and from April 2020 (T2—during lockdown). Semi‐structured interviews were conducted with 20 patients (66.9 ± 11.9 years old) undergoing HD for an average of 46.1 months (±39.5) in April 2020. Overall results suggested that dialysis adequacy and serum albumin levels decreased significantly at T2, while phosphorus levels increased. The findings from thematic analysis suggested several psychosocial negative impacts and impacts on disease and treatment‐related health behaviors (eg, difficulties managing dietary restrictions during the lockdown and diminished physical activity), which can partially explain these quantitative results. However, some patients were also able to find positive impacts in this experience and problem‐focused and emotional strategies were identified to cope with the demands of COVID‐19. Several recommendations have been made to mitigate patients’ emotional, relational, and educational unmet needs during the current pandemic and in the event of new outbreaks. 相似文献
93.
M. Teresa Gómez Hernández Marta Fuentes Gago Nuria Novoa Valentín Israel Rodríguez Alvarado Marcelo F. Jiménez López 《Cirugía espa?ola》2021,99(6):421-427
IntroductionRobotic surgery has become a safe and effective approach for the treatment of pulmonary surgical pathology. However, the adoption of new surgical techniques requires the evaluation of the learning curve. The objective of this study is to analyze the learning curve of robotic anatomical lung resections.MethodsRetrospective analysis of all robotic anatomical lung resections performed by the same surgeon between June 2018 and March 2020. The learning curve was evaluated using CUSUM charts to estimate trend changes in surgical time, surgical failure and the occurrence of post-operative cardiorespiratory complications throughout the sequence of cases.ResultsThe study included a total of 73 cases. The median duration of all complications was 120 min (interquartile range: 90-150 min), the prevalence of surgical failure was 23.29%, while 4/73 patients had any postoperative cardiorespiratory complication. Based on the CUSUM analysis, the learning curve was divided into 3 different phases: phase i (from the first to the 14th intervention), phase ii (between the 15th and 30th intervention) and phase iii (from the 31st intervention).ConclusionsThe learning curve for robotic anatomical lung resections can be divided into 3 phases. The technical competence that guarantees satisfactory perioperative outcomes was achived in phase iii from the 31st intervention. 相似文献
94.
M. Vives A. Hernández A.D. González J. Torres P. Cuesta T. Villen P. Carmona D. Nagore M. Serna U. Bengoetxea X. Borrat G. García de Casasola E. Sánchez R. Campo J. Mercadal 《Revista espa?ola de anestesiología y reanimación》2021,68(3):143-148
The use of ultrasound as a clinical diagnostic tool and guide of bedside procedures has become an indispensable examination in the acute critically ill patient. The training of professionals in minimum skills of knowledge, management and indications of use of ultrasound required to be defined by the Scientific Societies. The Intensive Care Ultrasound Working Group of the Spanish Society of Anesthesiology and Resuscitation (SEDAR), of the Spanish Society of Internal Medicine (SEMI) and the Spanish Society of Emergency Medicine (SEMES) has developed this consensus document in which the recommended training program and the minimum competencies to be achieved with regard to the use of Ultrasound in Intensive Care, Anesthesia and Emergency medicine are defined.This document defines the training program and the skills to acquire in order to achieve the diploma in lung, abdominal and vascular ultrasound. This document can serve as a guide to define the skills to be acquired in the training programs of residents (MIRs) of specialists working in intensive care, anesthesia, and emergency medicine. 相似文献
95.
Nicholas C Harvey Eric Orwoll Timothy Kwok Magnus K Karlsson Björn E Rosengren Eva Ribom Jane A Cauley Peggy M Cawthon Kristine Ensrud Enwu Liu Alfonso J Cruz-Jentoft Roger A Fielding Cyrus Cooper John A Kanis Mattias Lorentzon Claes Ohlsson Dan Mellström Helena Johansson Eugene McCloskey 《Journal of bone and mineral research》2021,36(7):1235-1244
Dual-energy X-ray absorptiometry (DXA)-derived appendicular lean mass/height2 (ALM/ht2) is the most commonly used estimate of muscle mass in the assessment of sarcopenia, but its predictive value for fracture is substantially attenuated by femoral neck (fn) bone mineral density (BMD). We investigated predictive value of 11 sarcopenia definitions for incident fracture, independent of fnBMD, fracture risk assessment tool (FRAX®) probability, and prior falls, using an extension of Poisson regression in US, Sweden, and Hong Kong Osteoporois Fractures in Men Study (MrOS) cohorts. Definitions tested were those of Baumgartner and Delmonico (ALM/ht2 only), Morley, the International Working Group on Sarcopenia, European Working Group on Sarcopenia in Older People (EWGSOP1 and 2), Asian Working Group on Sarcopenia, Foundation for the National Institutes of Health (FNIH) 1 and 2 (using ALM/body mass index [BMI], incorporating muscle strength and/or physical performance measures plus ALM/ht2), and Sarcopenia Definitions and Outcomes Consortium (gait speed and grip strength). Associations were adjusted for age and time since baseline and reported as hazard ratio (HR) for first incident fracture, here major osteoporotic fracture (MOF; clinical vertebral, hip, distal forearm, proximal humerus). Further analyses adjusted additionally for FRAX-MOF probability (n = 7531; calculated ± fnBMD), prior falls (y/n), or fnBMD T-score. Results were synthesized by meta-analysis. In 5660 men in USA, 2764 Sweden and 1987 Hong Kong (mean ages 73.5, 75.4, and 72.4 years, respectively), sarcopenia prevalence ranged from 0.5% to 35%. Sarcopenia status, by all definitions except those of FNIH, was associated with incident MOF (HR = 1.39 to 2.07). Associations were robust to adjustment for prior falls or FRAX probability (without fnBMD); adjustment for fnBMD T-score attenuated associations. EWGSOP2 severe sarcopenia (incorporating chair stand time, gait speed, and grip strength plus ALM) was most predictive, albeit at low prevalence, and appeared only modestly influenced by inclusion of fnBMD. In conclusion, the predictive value for fracture of sarcopenia definitions based on ALM is reduced by adjustment for fnBMD but strengthened by additional inclusion of physical performance measures. © 2021 The Authors. Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR). 相似文献
96.
Giuliante Felice Viganò Luca De Rose Agostino M. Mirza Darius F. Lapointe Réal Kaiser Gernot Barroso Eduardo Ferrero Alessandro Isoniemi Helena Lopez-Ben Santiago Popescu Irinel Ouellet Jean-Francois Hubert Catherine Regimbeau Jean-Marc Lin Jen-Kou Skipenko Oleg G. Ardito Francesco Adam René 《Annals of surgical oncology》2021,28(13):8198-8208
Annals of Surgical Oncology - The liver-first approach in patients with synchronous colorectal liver metastases (CRLM) has gained wide consensus but its role is still to be clarified. We aimed to... 相似文献
97.
98.
Escalante-Mañe Ana M. Hernández-Nuñez Emanuel Méndez-Novelo Roger I. Giácoman-Vallejos Germán González-Sánchez Avel A. Quintanilla-Mena Mercedes A. Romellón-Orozco Mariana E. Puch-Hau Carlos 《Bulletin of environmental contamination and toxicology》2022,108(3):526-531
Bulletin of Environmental Contamination and Toxicology - We report the chemical characterisation and toxic effects of municipal solid waste landfill leachates on the embryonic development of Danio... 相似文献
99.
Willy Palm Erin Webb Cristina Hernández-Quevedo Giada Scarpetti Suszy Lessof Luigi Siciliani Ewout van Ginneken 《Health policy (Amsterdam, Netherlands)》2021,125(3):341-350
This study identifies gaps in universal health coverage in the European Union, using a questionnaire sent to the Health Systems and Policy Monitor network of the European Observatory on Health Systems and Policies. The questionnaire was based on a conceptual framework with four access dimensions: population coverage, service coverage, cost coverage, and service access. With respect to population coverage, groups often excluded from statutory coverage include asylum seekers and irregular residents. Some countries exclude certain social-professional groups (e.g. civil servants) from statutory coverage but cover these groups under alternative schemes. In terms of service coverage, excluded or restricted services include optical treatments, dental care, physiotherapy, reproductive health services, and psychotherapy. Early access to new and expensive pharmaceuticals is a concern, especially for rare diseases and cancers. As to cost coverage, some countries introduced protective measures for vulnerable patients in the form of exemptions or ceilings from user chargers, especially for deprived groups or patients with accumulation of out-of-pocket spending. For service access, common issues are low perceived quality and long waiting times, which are exacerbated for rural residents who also face barriers from physical distance. Some groups may lack physical or mental ability to properly formulate their request for care. Currently, available indicators fail to capture the underlying causes of gaps in coverage and access. 相似文献
100.
Pablo Martinez-Perez Domingo Orozco-Beltrán Francisco Pomares-Gomez Juan L. Hernández-Rizo Anna Borras-Gallen Vicente F. Gil-Guillen Jose A. Quesada Adriana Lopez-Pineda Concepción Carratala-Munuera 《Atencion primaria / Sociedad Espa?ola de Medicina de Familia y Comunitaria》2021,53(2):101942
AimsTo validate a translated and culturally adapted version of the Morisky Medication Adherence Scale for use in Spanish population, and to examine the psychometric properties of this scale in patients with type 2 diabetes mellitus in Spain.DesignThis cross-sectional study was conducted in a single university hospital in Spain. Patients diagnosed with type 2 diabetes mellitus at least 1 year before inclusion, being treated with anti-diabetic medication were included.InterventionWe used the Spanish version of the scale to measure treatment adherence.Principal measurementsthree level categorical scale is broken down into low adherence (score of <6), medium adherence (score of 6 to <8) and high adherence (score of 8). To validate the questionnaire, we measured internal consistency through Cronbach's α, confirmed construct validity through an exploratory principal component analysis and assessed test–retest reliability.Results232 patients met the inclusion criteria. The Cronbach's α coefficient was 0.40 (95% CI 0.28–0.52). The exploratory principal component analysis showed three components. The intraclass correlation coefficient was 0.718 (95% CI 0.564–0.823).Conclusionsthe Spanish version of the Morisky Medication Adherence scale showed low internal consistency, the exploratory factor analysis identified three dimensions, and the test–retest reliability was acceptable, therefore, psychometric properties of MMAS-8 are not suitable for measuring medication adherence in type 2 diabetes mellitus patients from Spain. 相似文献