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81.
82.
帕金森病立体定向手术并发脑内出血的原因分析 总被引:2,自引:0,他引:2
目的:探讨帕金森病立体定向手术颅内出血并发症原因及对策。方法:自1999年4月至2003年3月我们对药物治疗效果不理想的510例帕金森病病人行立体定向毁损手术,术后出现颅内出血9例,其中毁损灶出血3例,穿刺道出血6例。结果:手术治疗4例.保守治疗5例。术后意识恢复但遗留偏瘫4例,经非手术治疗5例.恢复良好,未遗留明显功能障碍。全组无死亡病例。结论:采用磁共振结合微电极导向提高靶点定位精确度,减少微电极记录针道数,降低毁损温度,重视围手术期处理等措施,有助于降低颅内出血并发症的危险。 相似文献
83.
目的:探讨适合睫状体缝合复位术病人的护理方法。方法:对34例(34只眼)因外伤致睫状体分离和脱离导致低眼压,随后行睫状体缝合复位术的病人进行观察和护理。结果:32只眼术后1周至6个月眼压恢复正常,其中5只眼术后2~5个月内分别进行第二次手术或氩离子激光光凝而痊愈。视力改善者21例,无变化者13例。结论:睫状体缝合复位术是治疗外伤性睫状体分离和脱离的有效方法。术前行超声生物显微镜(UBM)检查、术后密切观察眼压变化并给予正确处理、做好心理护理和出院指导是确保手术成功的重要措施。 相似文献
84.
85.
红毛五加多糖对机体免疫功能的影响 总被引:17,自引:0,他引:17
本文研究红毛五加多糖成分对机体免疫功能的影响,实验结果表明红毛五加多糖可激发T、B-淋巴细胞的生物学效益。 相似文献
86.
The impact of coronary care unit on mortality from acute myocardial infarction in Hong Kong. A prospective randomized controlled study. 总被引:2,自引:0,他引:2
J S Hu 《中华医学杂志(英文版)》1990,103(2):101-106
A prospective concurrent study was made on 2 groups of patients suffering from acute myocardial infarction admitted at random into the Coronary Care Unit (CCU) or general wards (GW). After excluding those older than 70 years of age, the two groups were similarly matched according to their ages and clinical severity. Those who were initially treated in the CCU had a higher chance of survival from myocardial infarction as compared with those in the GW. The overall mortality was 15.3% (17/111) and 29.3% (27/92) respectively (P less than 0.02), and the risk of dying in the GW comparing to that in the CCU was 2.3 (95% confidence interval 1.1-4.8). Sudden death was more frequently encountered in those treated in the GW. Our findings strongly support the use of the CCU for patients below 70 years.
相似文献
87.
目的 探讨军人花粉症治疗的有效方法。方法 采用提高起始浓度和快速递增浓度 ,上臂外侧皮下注射的方法对 10 6位军人花粉症患者行快速免疫治疗 ,并对每一位患者治疗前后检测血清中总IgE和嗜酸细胞阳离子蛋白 (ECP)。 结果 治疗前后患者总IgE和ECP值有显著性差异。 10 6例患者经 1~ 3年随访复查 ,78例 2个以上发病季节未发作 ,或仅有轻微鼻痒、眼痒 ,18例症状减轻 ,发病时间缩短半月 ,10例症状无明显改善。显效 82例 ,有效 14例 ,无效 10例 ,总有效率为 90 .5 7%。结论 快速免疫治疗能使患者血清总IgE和ECP下降 ,对军人花粉症疗效好。 相似文献
88.
Gong-Lin Zhang Ming Zhang Ao Guo Gan-Sheng Wang Wen-Zheng Zhang Yu-Xiang Hu 《中华整形外科杂志》2008,24(1):29-31
OBJECTIVE: To evaluate the clinical application of microsurgical fascia latae flaps combined with rib and skin graft for reconstruction of the distal phalanx defect. METHODS: The phalanx wounds were sutured together like syndactyly. The autologeous rib was revised to repair the bone defect of distal phalanx. The fascia latae flap was used to cover the bone exposure with microvascular anastomoses and resurfaced by a meshed split-thickness skin graft. RESULTS: 5 cases were treated successfully. The fascia latae flaps were all survived with only skin graft necrosis at the distal end in one case. It was healed spontaneously. CONCLUSIONS: The fascia latae flap is nourished by the desending branch of the lateral circumflex femoral artery. The flaps has a good blood supply and can be easily obtained with a long vascular pedicle. The flap is ideal for the reconstruction of distal phalanx defect when combined with autologeous rib implant and skin graft. 相似文献
89.
Tsung-Hui Hu Jui-Wei Lin Chi-Sin Changchien Shang-Yun Liu Shue-Shian Chiou Jiin-Haur Chuang 《台湾医志》2003,102(10):707-714
BACKGROUND AND PURPOSE: Gastrointestinal stromal tumors (GISTs), identified by the presence of CD117 (KIT), were previously classified as gastric and intestinal smooth muscle tumors prior to the availability of immunohistochemical methods. This study evaluated the percentage of GISTs previously diagnosed as gastric smooth muscle tumors in our hospital during an 11-year period. METHODS: A total of 81 surgically resected gastric smooth muscle tumor specimens from 81 patients were collected from January 1986 to December 1997. Immunohistochemical studies were performed on these tumors with antibodies of CD34, CD117, smooth muscle actin (SMA), S-100, and desmin. RESULTS: Among the 81 tumors, 74 (91.4%) were CD117-positive and were classified as GISTs. Among the 74 GISTs, CD34 was positive in 72 tumors (97.3%), SMA was positive in 12 tumors (16.2%), desmin was positive in 5 tumors (6.7%), and S-100 was positive in 4 tumors (5.4%). The 7 tumors classified as non-GISTs had the following immunohistochemical characteristics: 1 was a CD117-negative CD34-positive stromal tumor (GINST) [1/81, 1.2%]; 3 were schwannomas with strong S-100-positive characteristics (3/81, 3.7%); and 3 were smooth muscle tumors with both SMA- and desmin-positive status (3/81, 3.7%). No clear relationship between CD117 or CD34 expression and prognosis was found for these tumors. CONCLUSIONS: The majority (91.4%) of gastric tumors originally diagnosed as gastric smooth muscle tumors were GISTs, except for small groups of smooth muscle tumors and schwannomas. 相似文献
90.
Shaoyi Chen Coleen M Atkins Chunli L Liu Ofelia F Alonso W Dalton Dietrich Bingren R Hu 《Journal of cerebral blood flow and metabolism》2007,27(5):939-949
In response to traumatic brain injury (TBI), neurons initiate neuroplastic processes through the activation of intracellular signaling pathways. However, the molecular mechanisms underlying neuroplasticity after TBI are poorly understood. To study this, we utilized the fluid-percussion brain injury (FPI) model to investigate alterations in the mammalian target of rapamycin (mTOR) signaling pathways in response to TBI. Mammalian target of rapamycin stimulates mRNA translation through phosphorylation of eukaryotic initiation factor 4E binding protein-1 (4E-BP1), p70 ribosomal S6 kinase (p70S6K), and ribosomal protein S6 (rpS6). These pathways coordinate cell growth and neuroplasticity via dendritic protein synthesis. Rats received sham surgery or moderate parasagittal FPI on the right side of the parietal cortex, followed by 15 mins, 30 mins, 4 h, 24 h, or 72 h of recovery. Using Western blot analysis, we found that mTOR, p70S6K, rpS6, and 4E-BP1 phosphorylation levels were significantly increased in the ipsilateral parietal cortex and hippocampus from 30 mins to 24 h after TBI, whereas total protein levels were unchanged. Using confocal microscopy to localize these changes, we found that rpS6 phosphorylation was increased in the parietal cortex and all subregions of the hippocampus. In accordance with these results, eIF4E, a key, rate-limiting mRNA translation factor, was also phosphorylated by mitogen-activated protein kinase-interacting kinase 1 (Mnk1) 15 mins after TBI. Together, these results suggest that changes in mRNA translation may be one mechanism that neurons use to respond to trauma and may contribute to the neuroplastic changes observed after TBI. 相似文献