全文获取类型
收费全文 | 2481篇 |
免费 | 168篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 32篇 |
儿科学 | 88篇 |
妇产科学 | 97篇 |
基础医学 | 231篇 |
口腔科学 | 51篇 |
临床医学 | 185篇 |
内科学 | 534篇 |
皮肤病学 | 105篇 |
神经病学 | 156篇 |
特种医学 | 108篇 |
外国民族医学 | 1篇 |
外科学 | 453篇 |
综合类 | 41篇 |
一般理论 | 2篇 |
预防医学 | 195篇 |
眼科学 | 33篇 |
药学 | 200篇 |
中国医学 | 23篇 |
肿瘤学 | 122篇 |
出版年
2023年 | 20篇 |
2022年 | 93篇 |
2021年 | 108篇 |
2020年 | 58篇 |
2019年 | 69篇 |
2018年 | 117篇 |
2017年 | 65篇 |
2016年 | 78篇 |
2015年 | 73篇 |
2014年 | 104篇 |
2013年 | 120篇 |
2012年 | 188篇 |
2011年 | 191篇 |
2010年 | 105篇 |
2009年 | 86篇 |
2008年 | 142篇 |
2007年 | 111篇 |
2006年 | 133篇 |
2005年 | 99篇 |
2004年 | 104篇 |
2003年 | 80篇 |
2002年 | 84篇 |
2001年 | 66篇 |
2000年 | 38篇 |
1999年 | 38篇 |
1998年 | 17篇 |
1997年 | 12篇 |
1996年 | 18篇 |
1995年 | 5篇 |
1994年 | 8篇 |
1993年 | 15篇 |
1992年 | 24篇 |
1991年 | 13篇 |
1990年 | 10篇 |
1989年 | 21篇 |
1988年 | 13篇 |
1987年 | 16篇 |
1986年 | 17篇 |
1985年 | 7篇 |
1984年 | 6篇 |
1983年 | 6篇 |
1980年 | 4篇 |
1979年 | 10篇 |
1978年 | 5篇 |
1977年 | 4篇 |
1975年 | 7篇 |
1971年 | 6篇 |
1970年 | 4篇 |
1965年 | 4篇 |
1961年 | 3篇 |
排序方式: 共有2657条查询结果,搜索用时 109 毫秒
21.
Despite rising interest in the health problems of the elderly, information on senescence-related alterations in essential metabolic pathways and their responses to various chemicals is scarce. Although peroxisomal pathways are involved in a multitude of cellular functions, little attention has been given to the potential relationship between senescence of these organelles and the process of aging and disease. Although the prevailing experimental evidence points to a decline in liver peroxisomal enzyme activities and a muted response to peroxisome-proliferating chemicals in aged animals, it is also evident that aged animals are more susceptible, in comparison to their young counterparts, to the hepatocarcinogenic effects of these chemicals. Furthermore, little is known about extraperoxisomal effects of peroxisome proliferators in aged animals. This review evaluates published studies on the impact of aging on basal hepatic peroxisomal metabolism, response to peroxisome proliferators, and changes in signal transduction pathways involved in these processes, with the aim of stimulating research efforts in this important area. The potential intricate relationship among senescent peroxisomes, aged hepatocytes, and health are also discussed. 相似文献
22.
Abdel Aal TM Youssef FG el-Hady HM Sabry NM Habib KS Saber JM 《The Journal of the Egyptian Public Health Association》1996,71(3-4):321-341
Three serological tests: Immunodiffusion (ID), Counterimmunoelectrophoresis (CIEP) and Enzyme-linked immunosorbent assay (ELISA) were used to study the role of crude adult worm antigen (CAWA) of Toxocara canis and each of its purified fractions in the serodiagnosis of human toxocariasis. Sensitivities of the three tests were lower in the ocular than in the visceral group, using different antigens. Purified fraction 1 showed more sensitive and specific reactions in the three tests, compared to CAWA or purified fraction 2 (P-F2) antigen. The other purified fractions (P-F3, P-F4 and P-F5) gave no positive reactions in any of the three tests. Using P-F1 antigen, ELISA was the most sensitive technique for diagnosis of both visceral and ocular toxocariasis followed by CIEP and then ID and the difference was statistically significant. However, CIEP was the most specific test followed by ELISA and lastly ID test. The ELISA test using Excretory-Secretory (E-S) larval antigen of Toxocara canis was less sensitive than the ELISA test using P-F1, although it was 100% specific. Thus, ELISA test using P-F1 is the test of choice for diagnosis of human toxocariasis, but when the specificity of a reaction is in doubt, CIEP test using the same antigen can be of value. 相似文献
23.
Pulmonary lymphangiectasia revisited 总被引:1,自引:0,他引:1
Bouchard S Di Lorenzo M Youssef S Simard P Lapierre JG 《Journal of pediatric surgery》2000,35(5):796-800
PURPOSE: Pulmonary lymphangiectasia (PL) is a rare, poorly documented disease characterized by abnormal pulmonary lymphatics. Although case reports are published, little is known about survivors past the neonatal period. METHODS: This is a retrospective review of histologically proven PL in fetuses, infants, and long term survivors since 1965. RESULTS: Eleven children (8 boys, 3 girls) and 8 aborted fetuses (7 male, 1 female) were identified. The fetuses weighed 463.4 g (177 to 681 g). Six were aborted between 19 to 24 weeks of gestation for multiple malformations or anencephaly, and 2 spontaneously aborted: one with PL only, the other with twin-twin transfusion syndrome. Clinical PL was diagnosed between 0 and 11 months of age. Six children died (2 neonatal, 4 within 10 days), 5 survived. Two deaths occurred after cardiac surgery. Among survivors, the symptomatology and frequency of admissions diminished over time. Symptoms included progressive respiratory distress, chronic cough, recurrent pneumonia, bronchial asthma, and choking. One child with bilateral chylothorax was later diagnosed with Noonan syndrome; 2 patients had minor cardiac malformations. Rapid deterioration occurred with mild respiratory infections with only supportive treatment available. Chest x-ray showed marked hyperinflation with interstitial infiltrate. CONCLUSIONS: This is the first long-term study of primary PL and will help counsel parents. Although fatal in the neonatal period, survival is possible if diagnosed past the neonatal period and improvement is expected. 相似文献
24.
Cluster munitions are weapons that scatter smaller sub-munitions intended to kill or mutilate on impact. They have been used by the Israeli army in the south of Lebanon and are now scattered over wide rural areas affecting its inhabitants. Because of their easily “pickable” nature, sub-munitions can inflict injuries to the head and face regions. In this study, we aimed to explore the head and face injuries along with their clinical features in a group of Lebanese patients who suffered from such injuries due to a sub-munition’s detonation. The study included all the cases reported between 14 August 2006 and 15 February 2013, with head and face injuries related to cluster bombs. Injuries were classified into brain, eye, otologic and auditory impairments, oral and maxillofacial, and skin and soft-tissue injuries. Psychological effects of these patients were also examined as for post-traumatic stress disorder, major depressive disorder, generalized anxiety disorder and acute stress syndrome. During the study period, there were 417 casualties as a result of cluster munitions’ blasts. Out of the total number of victims, 29 (7 %) were injured in the head and the face region. The convention on cluster munitions of 2008 should be adhered to, as these inhumane weapons indiscriminately and disproportionately harm innocent civilians, thereby violating the well-established international principles governing conflict and war today. 相似文献
25.
26.
27.
28.
Previous studies have suggested a trait-like association between neighborhood deprivation and alcohol consumption. However, it is not known whether temporarily manipulating poverty and affluence states by exposure to stimuli signifying resource-scarcity or resource-wealth would influence alcohol-seeking behavior. Here, we aimed to investigate whether implicit exposure to affluence and poverty-related pictures would influence beer consumption. Participants in a “poverty” group viewed pictures depicting impoverished environments, and participants in an “affluence” group viewed images of wealthy environments. After priming, participants were provided with nonalcoholic beer (which they were told was alcohol-containing beer) and orange juice under the guise of a bogus taste test, to measure their alcohol-seeking behavior. Results showed that priming participants with a resource-scarce environment led to an increase in beer consumption (as a percentage of total fluid consumed), compared to priming with a resource-rich environment. The same pattern of results was obtained in both a Western European sample (Experiment 1) and a West Indian sample (Experiment 2). In Experiment 2, we also tested whether risk-taking behavior, measured by the Balloon Analogue Risk Task, was influenced by the environmental priming; no differences between groups were observed. These results provide the first experimental evidence that manipulation of poverty-affluence state, by brief exposure to pictures of impoverished or wealthy neighborhoods, can influence alcohol-seeking behavior in adult social drinkers. 相似文献
29.
This review presents a comprehensive picture of the zoonotic parasitic diseases in Egypt, with particular reference to their relative prevalence among humans, animal reservoirs of infection, and sources of human infection. A review of the available literature indicates that many parasitic zoonoses are endemic in Egypt. Intestinal infections of parasitic zoonoses are widespread and are the leading cause of diarrhea, particularly among children and residents of rural areas. Some parasitic zoonoses are confined to specific geographic areas in Egypt, such as cutaneous leishmaniasis and zoonotic babesiosis in the Sinai. Other areas have a past history of a certain parasitic zoonoses, such as visceral leishmaniasis in the El-Agamy area in Alexandria. As a result of the implementation of control programs, a marked decrease in the prevalence of other zoonoses, such as schistosomiasis and fascioliasis has been observed. Animal reservoirs of parasitic zoonoses have been identified in Egypt, especially in rodents, stray dogs and cats, as well as vectors, typically mosquitoes and ticks, which constitute potential risks for disease transmission. Prevention and control programs against sources and reservoirs of zoonoses should be planned by public health and veterinary officers based on reliable information from systematic surveillance. 相似文献
30.