女性吸毒者心理防御机制及心理健康状况研究

目的探讨女性吸毒者的心理防御机制与心理状况及二者的关系.方法分别用防御方式问卷(DSQ)和症状自评量表(SCL-90),对110名女性吸毒者(研究组)和41名女大学生(对照组)进行调查.结果研究组不成熟防御机制、中间型防御机制和掩饰因子评分(4.83±0.97,4.99±0.75,5.98±1.17)显著高于对照组(3.95±0.68,4.26±0.73,5.41±1.34)(P＜0.01或P＜0.05);研究组SCL-90中9个因子评分均显著高于对照组(P＜0.01);相关分析发现,研究组不成熟防御机制与SCL-90中9个因子均存在非常显著正相关(P＜0.01),中间型防御机制与SCL-90中的强迫、偏执、躯体化、抑郁存在显著正相关(P＜0.01或P＜0.05),掩饰因子与SCL-90中的敌对、偏执、强迫呈显著正相关(P＜0.01或P＜0.05).结论女性吸毒者过多地使用不成熟防御机制及中间型防御机制,心理状况差,且二者存在明显的相关性.     

介绍一种针头拔出器

临床工作中，医务人员在分离注射器、输液器针头时，常用止血钳、纱布或直接用手分离，这些方法易被针头刺伤。在许多医院使用自动针头毁形器。现介绍一种低成本、易制作及安装的简易针头拔出器。     

大白鼠尾动脉吻合实验的方法与体会

报告了960次大白鼠尾动脉吻合实验,采用端端吻合法800次,即刻通畅率96.5％,套叠吻合法160次,即刻通畅率100％。作者认为利用大白鼠尾动脉作吻合训练,具有节省动物、可多次操作、无需无菌条件、操作简单易行等优点,并介绍了操作方法和注意点。     

曼氏血吸虫与日本血吸虫交叉免疫原性的血清学实验研究

以曼氏血吸虫的虫卵和成虫免疫家兔后所产生的特异性抗体,可用以日本血吸虫虫卵、尾蚴和成虫为抗原分别进行的COP,CHR和ELACIEP测出,表明两种人体血吸虫存有显著的交叉抗原成分。应用此种血清交叉反应性,以检测抗异种人体血吸虫的抗体,似有效而可取的,可用以辅助诊断援外回国人员是否感染国外人体血吸虫病。     

Recent Advances in Structure-Based Virtual Screening of G-Protein Coupled Receptors

In addition to the rhodopsin crystal structure, high-resolution crystal structures of ligand-mediated G-protein-coupled receptors (GPCRs) have recently become available, and these have become attractive templates for developing homology models of several GPCRs of therapeutic interest. These crystal structures and the homology models derived from them have provided significant insights into ligand–receptor interactions. Moreover, several studies have demonstrated that the structural models are indeed suitable for virtual screening of compound databases to identify new ligands for various GPCRs. Recent examples of such virtual screening against GPCRs are discussed in this review.     

Feasibility of treating hyperfibrinogenemia with intermittently administered batroxobin in patients with ischemic stroke/transient ischemic attack for secondary prevention.

This study evaluated the safety and efficacy of batroxobin in treating hyperfibrinogenemia for secondary stroke prevention. Patients with ischemic stroke or transient ischemic attack (TIA) were measured for plasma fibrinogen levels. Selected participants had concomitant hyperfibrinogenemia (plasma fibrinogen > or = 3.0 g/l). Patients enrolled between 1 July 2003 and 31 December 2004 were treated with batroxobin; patients enrolled between 1 January 2002 and 30 June 2003 were treated without batroxobin. Batroxobin was administered intermittently via intravenous injection at 3-monthly intervals. Patients in both groups were followed for 1 year. Any cerebrovascular events and suspected adverse events were recorded. In total, 112 ischemic stroke/TIA patients with concomitant hyperfibrinogenemia were enrolled, 52 being treated with batroxobin and 60 without batroxobin. Six patients (11.5%) with batroxobin and 16 patients (26.7%) without batroxobin had recurrent cerebral ischemic events during follow-up. Stroke/TIA recurrence in patients without batroxobin was higher than that in patients with batroxobin (P < 0.05). Two patients with batroxobin and two patients without batroxobin developed hemorrhagic stroke during follow-up. There were five deaths (9.6%) in the batroxobin group, and seven deaths (11.7%) in the nonbatroxobin group during follow-up (P > 0.05). Intermittent intravenous injection of batroxobin can efficiently reduce the risk for stroke/TIA recurrence in patients with concomitant hyperfibrinogenemia.     

无线网络技术在医学仪器中的应用

简要介绍无线网络技术的原理、特点及其在医学仪器中的应用.     

妊高征与眼底视网膜病变的临床探讨

目的 :探讨妊高征患者临床特征与视网膜病变的关系。方法 :观察 2 2 0例妊高征患者的眼底情况。结果 :视网膜病变与水肿关系不密切 ,与平均动脉压、蛋白尿的严重程度、病程及红细胞压积有密切关系 ;有眼底改变者 118例 ,占 5 0 .3%。结论 :眼底镜检查是临床上借以了解视网膜血管的常用方法 ,并可反映妊高征病情的程度 ,为产程处理提供依据