全文获取类型
收费全文 | 396篇 |
免费 | 32篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 35篇 |
妇产科学 | 20篇 |
基础医学 | 21篇 |
口腔科学 | 20篇 |
临床医学 | 40篇 |
内科学 | 59篇 |
皮肤病学 | 6篇 |
神经病学 | 38篇 |
特种医学 | 12篇 |
外科学 | 129篇 |
综合类 | 7篇 |
预防医学 | 2篇 |
眼科学 | 10篇 |
药学 | 17篇 |
中国医学 | 2篇 |
肿瘤学 | 7篇 |
出版年
2023年 | 8篇 |
2022年 | 3篇 |
2021年 | 23篇 |
2020年 | 8篇 |
2019年 | 9篇 |
2018年 | 19篇 |
2017年 | 14篇 |
2016年 | 17篇 |
2015年 | 18篇 |
2014年 | 21篇 |
2013年 | 26篇 |
2012年 | 29篇 |
2011年 | 40篇 |
2010年 | 8篇 |
2009年 | 14篇 |
2008年 | 26篇 |
2007年 | 29篇 |
2006年 | 34篇 |
2005年 | 25篇 |
2004年 | 24篇 |
2003年 | 16篇 |
2002年 | 8篇 |
2001年 | 3篇 |
2000年 | 1篇 |
1998年 | 1篇 |
1996年 | 2篇 |
1987年 | 1篇 |
1985年 | 1篇 |
排序方式: 共有428条查询结果,搜索用时 15 毫秒
71.
72.
Elif Bahat Ozdogan Mehmet Mutlu Secil Arslansoyu Camlar Gülcin Bayramoglu Sebnem Kader Yakup Aslan 《Pediatrics and neonatology》2018,59(3):305-309
Background
It is controversial to test for urinary tract infection (UTI) in patients with unexplained indirect hyperbilirubinemia in the first 2 weeks of life. We aimed to study the prevalence and significance of UTIs in such neonates who were requiring phototherapy.Methods
Subjects were 2- to 14-day-old neonates with indirect bilirubin levels above phototherapy limit with no other abnormality in their bilirubinaemia-related etiologic workup. UTI was diagnosed by 2 consecutive positive cultures obtained by catheterisation, documenting growth of >10,000 colonies of the same microorganism with consistent antibiograms. The UTI (+) patients were evaluated by renal ultrasonography (US), and some were followed up for possible recurrent UTI.Results
262 neonates were included in the study. UTI prevalence was 12.2%, and bacteraemia was 6.2% among UTI (+) patients. The two most common pathogens (81.2%) were Escherichiacoli and Klebsiella. pneumonia. All UTI (+) patients had undergone US, revealing 12.5% pelvicaliectasis, other 12.5% increased renal parenchymal echogenicity, 3.1% concurrent pelvicaliectasis and increased renal parenchymal echogenicity. 53.1% of UTI (+) patients had undergone follow-up, after which 23.5% recurrent UTI were found at the end of a mean of 52 months.Conclusion
We suggest that the neonates with unexplained pathological jaundice should be tested for possible UTI. Consequently, all newborns with UTI shall be evaluated by the urinary US and followed up for recurrent UTI. 相似文献73.
Mehmet Ozgur Akkurt And Yavuz Serenat Eris Yalcin Iltac Akkurt Ozerk Turel Turan Yakup Yalcin 《The journal of maternal-fetal & neonatal medicine》2017,30(15):1855-1860
Aim: To investigate short- and long-term outcomes in women undergoing cesarean myomectomy (CM).Methods: This was a retrospective study that explored short-term outcomes of women, who underwent cesarean operations with or without myomectomies (CM controls) in a single tertiary center throughout a 6-year-period. For long-term outcomes, the mean duration of follow-up was 6.3?±?1.0 years.Results: There were no differences among the CM (n=?91) and control groups (n?=?60) considering mean change in hemoglobin and hematocrit levels, hemorrhage, as well as requirement for blood transfusions with a slightly increased operative time. Multiple myomas, and cervical and cornual localization were associated with an increased drop of hemoglobin and hematocrit (p?0.05). Subsequent pregnancy and recurrence rates were 35% (32/91) and 5.5% (5/91), respectively. Preterm delivery (n?=?1, 3.1%), uterine dehiscence (n?=?1, 3.1%), placenta previa (n?=?1, 3.1%) and mild-to-severe post-CM adhesions (n?=?8, 25%) were observed in subsequent pregnancies. Recurrence was identified in five of the nonpregnant (5.5%) women, and three of these (4.1%) underwent an additional major surgery. There was no recurrence in subsequent pregnancies.Conclusion: The recurrence of myoma was relatively low following CM. Subsequent pregnancy is protective for recurrence of myoma without increased adhesion formation and obstetric complications. 相似文献
74.
Left ventricular non‐compaction is a rare form of cardiomyopathy believed to be the result of intrauterine arrest of compaction of the endomyocardial morphogenesis, leading to persistence of the embryonic myocardium. Clinical manifestations are highly variable, ranging from no symptoms to a progressive deterioration in cardiac function that results in congestive heart failure, systemic thromboemboli, arrhythmias, and sudden cardiac death. Presented here is the case of a 4‐year‐old child with a history of aborted sudden cardiac death. Following resuscitation, he was admitted to the intensive care unit with neurologic sequelae that regressed later on. Transthoracic echocardiography and magnetic resonance imaging showed numerous prominent trabeculations and deep intertrabecular recesses at the apical and anterolateral region of the left ventricle. Electrophysiologic study showed polymorphic ventricular tachycardia. An implantable cardioverter–defibrillator (ICD) was implanted following clinical recovery. Five months after implantation, appropriate ICD shock due to ventricular fibrillation was documented. 相似文献
75.
Abstract – The aim of this study was to investigate the long-term effects of the use of human cadaveric solvent-dehydrated bone graft and duramater as a barrier membrane for the treatment of oroantral communication. Standard oroantral osseous defects were created in five minipigs. Subjects received cancellous bone graft in the form of block or microchips, duramater or a combination of bone and membrane. Uneventful healing was achieved in all of the subjects, clinically including the control site which did not receive any material. The operated bone segments were evaluated both by radiological and histological examinations after 6 months. Radiological evaluation was carried out using bone density analysis software and histological evaluation made by light microscopy. Radiological and histological results revealed that bone grafting of oroantral osseous defects improved the bone quality. However, application of duramater did not change this activity, both alone or combined with bone grafts. Within the limits of this experimental study, although solvent-dehydrated bone grafts were found superior and could be applied for the healing of osseous oroantral defects, resorbable membranes did not contribute to this process. 相似文献
76.
Yakup Ustün Murat Gündüz Ozgür Erdo?an M Emre Benlidayi 《Journal of oral and maxillofacial surgery》2006,64(9):1353-1358
PURPOSE: The aim of this study was to compare the use of dexmedetomidine with the use of midazolam during intravenous conscious sedation in third molar surgery. PATIENTS AND METHODS: Twenty healthy patients with symmetrically impacted mandibular third molars were included in this double-blind, crossover, randomized study. Either dexmedetomidine (group D) (4 microg.kg(-1).h(-1)) or midazolam (group M) (0.4 mg.kg(-1).h(-1)) was administered intravenously for 15 minutes before the first operation. At the second operation, the other agent was applied. Cardiorespiratory data were collected. The intraoperative sedation level, patient cooperation, and postoperative performance were scored and any pain reaction during the local anesthetic injection was recorded. Visual analog scales were additionally used for the subjective assessment of pain and patient satisfaction. Amnesia was evaluated by the patients' ability to recall the objects shown during the operations and the local anesthetic injection. Patients' preferences were recorded during the interview at the end of the second operations. RESULTS: The mean heart rate and blood pressure measurements were significantly lower in group D. There was no significant difference in the respiratory findings. A significantly higher number of patients showed pain reactions in group M. Sedation level, postoperative performance, and VAS pain scores were not statistically significant, whereas the differences in cooperation score and VAS for patient satisfaction were significant. Adequate amnesia was obtained in group M, however, no amnesia was demonstrated in group D. Sixty-five percent of the patients indicated a preference for dexmedetomidine sedation. CONCLUSION: Dexmedetomidine may be a remarkable alternative to midazolam for intravenous sedation because it seems to be a reliable and safe method, with additional analgesic effect providing a satisfactory sedation level without any serious side effects during impacted third molar surgery. 相似文献
77.
Yasemin Gunduz K?yasettin Asil Yakup Ersel Aksoy La?in Tatl? Ayhan 《Korean journal of radiology》2014,15(4):439-442
Median arcuate ligament syndrome is an anatomic and clinical entity characterized by dynamic compression of the proximal celiac artery by the median arcuate ligament, which leads to postprandial epigastric pain, vomiting, and weight loss. These symptoms are usually nonspecific and are easily misdiagnosed as functional dyspepsia, peptic ulcer disease, or gastropathy. In this report, we presented a 72-year-old male patient with celiac artery compression syndrome causing recurrent abdominal pain associated with gastric ulcer and iron deficiency anemia. This association is relatively uncommon and therefore not well determined. In addition, we reported the CT angiography findings and three-dimensional reconstructions of this rare case. 相似文献
78.
Kahraman
ztürk Mehmet Baydar Yakup Alpay Aye encan Osman Orman Serkan Aykut 《Acta orthopaedica et traumatologica turcica》2022,56(2):105
Objective:This study aimed to evaluate clinical results, femoral head survival, and the need for total hip arthroplasty (THA) in patients with precollapse osteonecrosis of the femoral head (OFH) (Steinberg stage II and III) treated by free vascularized fibula graft (FVFG) application.Methods:We retrospectively reviewed 54 hips of 47 patients (39 males, eight females; mean age 36 ± 14 years) who underwent FVFG due to OFH, with at least two years of follow-up. The patient data, including Harris Hip Score (HHS), Visual Analogue Scale (VAS), and conversion to THA, were documented.Results:The right hip of 26 patients and the left hip of 28 patients were involved. Bilateral FVFG surgery was performed on seven patients due to bilateral OFH. The mean follow-up time was 5.5 (range 2-14) years. Survival of the femoral head was observed in 39 hips (72.2%), while the femoral head collapse was observed in 15 femoral heads (27.8%). The mean preoperative HHS increased from 46.5 (range = 12-85) to 86.5 (range = 33-100) postoperatively (P < 0.001). The mean preoperative VAS score improved from 8.2 (range = 2-10) to 1.3 (range = 0-10) postoperatively (P < 0.001). THA was performed on seven hips at a mean follow-up time of 1.8 years (range = 0.7–3.3). There was no significant difference in the collapse rate between unilateral or bilateral OFH (P = 0.175). A higher survival rate was observed in the Steinberg stage II femoral head patients compared to the stage III femoral head (P = 0.021).Conclusion:This study has shown that FVFG surgery can be a good option for managing patients with Steinberg stage II and III precollapse OFH to prevent femoral head collapse and joint function. 相似文献
79.
Huseyin Oflaz Aydin Turkmen Faruk Turgut Burak Pamukcu Sabahattin Umman Adem Ucar Yakup Akyol Sami Uzun Rumeyza Kazancioglu Ramazan Kurt Mehmet S. Sever 《Transplant international》2006,19(4):333-337
Endothelial dysfunction is an early key event in the development of atherosclerotic cardiovascular disease observed in chronic renal failure patients. The role of renal transplantation (RTx) on endothelial dysfunction is still unclear. The aim of this study was to evaluate the endothelial function of chronic renal failure patients before RTx (while they were on hemodialysis, HD), and after RTx (at the 6th and 12th months) by a noninvasive method, brachial arterial ultrasound. A total of 22 (17 male, mean age: 33.9 +/- 11.6 years) RTx recipients were enrolled in the study. Endothelium-dependent vasodilation (EDD) was assessed by establishing reactive hyperemia. EDD prior to transplantation was significantly lower when compared with EDD measured at the 6th and 12th months after RTx (EDD pretransplantation: 6 +/- 3.7%, EDD at the 6th month of RTx: 8.3 +/- 2.3% and EDD at the 12th month of RTx: 12.1 +/- 3.6%, P < 0.001). When the EDD values measured at the 6th and 12th months of RTx were compared, measurements of the 12th month were found significantly higher than those of the 6th month (P < 0.001). Our results also showed that RTx has provided improvement in endothelial function by eliminating the uremic environment although not in the early post-RTx period. 相似文献
80.
Ihsan Ergun Gokhan Kabacam Yakup Ekmekci Ozden Tulunay Kenan Keven Neval Duman 《Nephrology, dialysis, transplantation》2005,20(6):1269-1270