全文获取类型
收费全文 | 2019篇 |
免费 | 94篇 |
国内免费 | 25篇 |
专业分类
耳鼻咽喉 | 41篇 |
儿科学 | 65篇 |
妇产科学 | 13篇 |
基础医学 | 237篇 |
口腔科学 | 49篇 |
临床医学 | 234篇 |
内科学 | 319篇 |
皮肤病学 | 38篇 |
神经病学 | 111篇 |
特种医学 | 244篇 |
外科学 | 257篇 |
综合类 | 26篇 |
一般理论 | 2篇 |
预防医学 | 155篇 |
眼科学 | 56篇 |
药学 | 213篇 |
中国医学 | 4篇 |
肿瘤学 | 74篇 |
出版年
2022年 | 11篇 |
2021年 | 14篇 |
2020年 | 13篇 |
2019年 | 24篇 |
2018年 | 46篇 |
2017年 | 20篇 |
2016年 | 42篇 |
2015年 | 28篇 |
2014年 | 46篇 |
2013年 | 90篇 |
2012年 | 77篇 |
2011年 | 79篇 |
2010年 | 76篇 |
2009年 | 54篇 |
2008年 | 74篇 |
2007年 | 102篇 |
2006年 | 98篇 |
2005年 | 87篇 |
2004年 | 80篇 |
2003年 | 40篇 |
2002年 | 36篇 |
2001年 | 62篇 |
2000年 | 63篇 |
1999年 | 49篇 |
1998年 | 45篇 |
1997年 | 41篇 |
1996年 | 48篇 |
1995年 | 28篇 |
1994年 | 24篇 |
1993年 | 34篇 |
1992年 | 31篇 |
1991年 | 36篇 |
1990年 | 44篇 |
1989年 | 47篇 |
1988年 | 45篇 |
1987年 | 42篇 |
1986年 | 29篇 |
1985年 | 34篇 |
1984年 | 24篇 |
1983年 | 32篇 |
1982年 | 27篇 |
1981年 | 18篇 |
1980年 | 19篇 |
1979年 | 14篇 |
1977年 | 18篇 |
1976年 | 27篇 |
1975年 | 13篇 |
1974年 | 11篇 |
1970年 | 11篇 |
1968年 | 11篇 |
排序方式: 共有2138条查询结果,搜索用时 15 毫秒
21.
Hilde Vandenneucker Luc Labey Jan Victor Jos Vander Sloten Kaat Desloovere Johan Bellemans 《Knee surgery, sports traumatology, arthroscopy》2014,22(10):2560-2568
Purpose
Although controversy still remains, isolated patellofemoral arthroplasty recently gained in popularity as a treatment option for patellofemoral osteoarthritis. It has compared to total knee arthroplasty the advantage of preserving the tibiofemoral articulation, which in theory would allow the preservation of natural tibiofemoral kinematics. Today, however, no data exist to support this assumption. This study was therefore performed in order to investigate the effect of isolated patellofemoral arthroplasty on the native three-dimensional tibiofemoral kinematic behaviour and whether a change in patellar thickness would have an influence.Methods
Six fresh-frozen cadavers were fixed on a custom-made mechanical knee rig. Full 3D kinematics was analysed during passive flexion–extension cycles, open chain extension, with and without mechanical resistance, as well as deep knee squats, using infrared motion capture cameras and retroflective markers. Measurements were taken for the native knee and after prosthetic trochlear resurfacing with and without patellar resurfacing in three different patellar thicknesses.Results
Compared to the natural knee, patellofemoral arthroplasty resulted in significant changes in tibiofemoral kinematics, which were most pronounced in the most loaded motor tasks. Increased internal tibial rotation was noted in the mid- and high flexion ranges, reaching at 120° of flexion a mean difference of 4.5° ± 4.3° (p < 0.0001) during squat motion, over the whole flexion range during open chain motion and in deeper flexion beyond 50° (mean at 70°, 1.9° ± 3.7°) during resisted open chain. During squats, also, a more posterior translation of the lateral femoral condyle was observed. The effect was accentuated in case of patella overstuffing, whereas kinematics was closer to normal with patellar thinning.Conclusion
Isolated patellofemoral arthroplasty alters natural tibiofemoral kinematics, and the effects become more pronounced in case of increased patellar thickness. Therefore, it might be recommended to aim for a slight over-resection of patellar bone if sufficient bone stock is available. 相似文献22.
Incidence of end-stage renal disease in medically treated patients with severe bilateral atherosclerotic renovascular disease. Atherosclerotic renovascular disease is an important cause of end-stage renal disease (ESRD). The exact incidence of ESRD and the rate of decline in glomerular filtration rate (GFR) in patients with this condition is unknown. We report the mortality, the rate of decline in renal function, and incidence of ESRD in 51 patients with bilateral atherosclerotic renovascular disease followed-up for a median period of 52 months. None of these patients had undergone any surgical or radiological intervention. Renal function was determined by serial measurements of serum creatinine. Bilateral atherosclerotic renovascular disease was associated with a high mortality rate; the crude mortality rate at 60 months was 45%. Assessment of renal function showed impaired renal function at time of angiography and a nonuniform and variable decline in renal function during the period of observation. The median GFR decreased from 39 mL/min (range, 15 to 80 mL/min) at time of angiography to 31 mL/min (range, 10 to 70 mL/min) and 24 mL/min (range, 10 to 40 mL/min) at 24 and 60 months, respectively (P < 0.05). The calculated mean rate of decline in GFR for all patients was 4 mL/min/yr (range, 1 to 16 mL/min/yr). Over the 5 years, there was a progressive increase in the incidence of ESRD. Of the original 51 patients who underwent angiography, six patients reached ESRD. The crude incidence of ESRD was, therefore, 12%. Patients who reached ESRD were characterized by advanced azotemia at the time of angiography (median GFR, 25 mL/min) and a rapid decline in GFR (8 mL/min) compared with patients who did not reach ESRD during the observation period (median GFR, 43 mL/min and an average rate of decline GFR of 3 mL/min). 相似文献
23.
Society for Ambulatory Anesthesia guidelines for the management of postoperative nausea and vomiting
Gan TJ Meyer TA Apfel CC Chung F Davis PJ Habib AS Hooper VD Kovac AL Kranke P Myles P Philip BK Samsa G Sessler DI Temo J Tramèr MR Vander Kolk C Watcha M;Society for Ambulatory Anesthesia 《Anesthesia and analgesia》2007,105(6):1615-28, table of contents
The present guidelines were compiled by a multidisciplinary international panel of individuals with interest and expertise in postoperative nausea and vomiting (PONV) under the auspices of The Society of Ambulatory Anesthesia. The panel critically evaluated the current medical literature on PONV to provide an evidence-based reference tool for the management of adults and children who are undergoing surgery and are at increased risk for PONV. In brief, these guidelines identify risk factors for PONV in adults and children; recommend approaches for reducing baseline risks for PONV; identify the most effective antiemetic monotherapy and combination therapy regimens for PONV prophylaxis; recommend approaches for treatment of PONV when it occurs; and provide an algorithm for the management of individuals at increased risk for PONV. 相似文献
24.
25.
26.
Hysterosalpingography was performed in 31 patients by means of a low-dose scanning-beam digital radiographic system. The technique permits adequate evaluation of gynecologic abnormalities while allowing significant reduction in radiation: 2.4-mR (6.1 X 10(-7) C/kg) exposure to the skin and 0.7-mrad (7 X 10(-6) Gy) mean dose to the ovaries per image obtained. Sixteen patients demonstrated readily recognizable and documented abnormalities, corroborated by laparoscopy, laparotomy, or other supportive evidence. 相似文献
27.
Magnuson JE; Brown ML; Hauser MF; Berquist TH; Fitzgerald RH Jr; Klee GG 《Radiology》1988,168(1):235-239
When infection of prosthetic orthopedic implants is suspected, optimal management requires accurate confirmation or exclusion of infection. The authors retrospectively studied 98 patients with possible infection who underwent scanning with indium-111-labeled white blood cells (WBCs) and subsequently underwent surgery within 14 days. At surgery, 50 patients had infections, as determined by means of culture or histologic results. The diagnostic accuracy of In-111 scanning was compared with that of plain radiography, arthrography, three-phase bone scanning, and various clinical and laboratory findings classically associated with infection. Positive findings on In-111 WBC scans and elevated erythrocyte sedimentation rates were found to be the most predictive variables in the diagnosis of septic prostheses (P less than or equal to .001 and P less than or equal to .002, respectively). Likelihood ratio analysis more clearly demonstrated the superiority of In-111 WBC scanning, with positive and negative scans yielding likelihood ratios of 5.0 and 0.16, respectively. 相似文献
28.
Omesh P I Gupta Eric D Weichel Carl D Regillo Mitchell S Fineman Richard S Kaiser Allen C Ho J Arch McNamara James E Vander 《Ophthalmic surgery, lasers & imaging》2007,38(4):270-275
BACKGROUND AND OBJECTIVE: To report postoperative complications in eyes undergoing 25-gauge pars plana vitrectomy (PPV). PATIENTS AND METHODS: Seventy consecutive eyes that underwent 25-gauge PPV for various indications, including epiretinal membrane, non-clearing vitreous hemorrhage, and idiopathic macular hole, and had a minimum follow-up of 12 weeks were reviewed retrospectively. Main outcome measures included best-corrected Snellen visual acuity, intraocular pressure (IOP), intraoperative complications, and postoperative complications. RESULTS: The mean visual acuity improved from 20/368 preoperatively to 20/105 postoperatively (P < .00005). Intraoperative complications included retinal tears in 2 eyes (2.9%). Postoperative complications included cataract progression in 17 eyes (42.5%), cystoid macular edema exacerbation in 5 eyes (7.1%), and retinal detachment in 1 eye (1.4%). Postoperative day 1 IOP was statistically lower than preoperative IOP in fluid-filled eyes (P = .031) but not in eyes filled with intravitreal air (P = .30) or gas (P = .52). Sclerotomy sutures were required intraoperatively in 5 eyes (7.1%) and postoperative day 1 hypotony was noted in 4 eyes (5.7%). All of these complications were noted in fluid-filled eyes except for one case of postoperative day 1 hypotony with gas tamponade. CONCLUSIONS: Intraoperative and postoperative complications were rare in this series of 25-gauge PPV. Postoperative cataract progression and hypotony were the most common complications. Fluid-filled eyes appear to have a higher risk of wound leakage and postoperative hypotony after 25-gauge PPV than eyes with air or gas tamponade. 相似文献
29.
Ionic liquids are largely used to leach metals from primary (ores) and secondary sources (end-of-life products). However, dry ionic liquids with a carboxylic function on the cation have not yet been used to leach metals at temperature above 100 °C and under atmospheric pressure. The ionic liquid betainium bis(trifluoromethylsulfonyl)imide, [Hbet][Tf2N], was used in the dry state to recover neodymium, dysprosium and cobalt from NdFeB magnets and NdFeB production scrap. The magnets and the scrap were crushed, milled and roasted before being leached above 100 °C. Recovery efficiencies below 10% and a lack of selectivity for all the parameters tested pointed to the importance of water in the dissolution process. The influence of the viscosity of the ionic liquid and the composition of the metal oxides after roasting was investigated as well. Although the dissolution of pure metal oxides was faster than the dissolution of the magnets, the low leaching efficiencies could not be attributed to the composition and crystal structure of the samples, since magnets roasted with the same protocol have already been successfully leached in the past, albeit in the presence of water. The role of water on the mass transfer and on the coordination of the metals was studied by viscometry and by spectroscopic methods, respectively. It is shown that for leaching of rare earths with [Hbet][Tf2N], the presence of ligands such as water is mandatory to saturate the first coordination sphere of the dissolved rare-earth ions. This paper provides new insights in the dissolution mechanism of metal oxides by [Hbet][Tf2N] at leaching temperatures higher than those typically used in hydrometallurgical leaching processes.Recovery of neodymium, dysprosium and cobalt from NdFeB magnets with the dry ionic liquid [Hbet][Tf2N] was investigated at 175 °C and atmospheric pressure. 相似文献
30.