全文获取类型
收费全文 | 2813篇 |
免费 | 170篇 |
国内免费 | 32篇 |
专业分类
耳鼻咽喉 | 18篇 |
儿科学 | 26篇 |
妇产科学 | 184篇 |
基础医学 | 349篇 |
口腔科学 | 99篇 |
临床医学 | 277篇 |
内科学 | 619篇 |
皮肤病学 | 33篇 |
神经病学 | 283篇 |
特种医学 | 138篇 |
外科学 | 490篇 |
综合类 | 5篇 |
一般理论 | 1篇 |
预防医学 | 87篇 |
眼科学 | 62篇 |
药学 | 97篇 |
中国医学 | 1篇 |
肿瘤学 | 246篇 |
出版年
2024年 | 8篇 |
2023年 | 31篇 |
2022年 | 68篇 |
2021年 | 138篇 |
2020年 | 77篇 |
2019年 | 89篇 |
2018年 | 117篇 |
2017年 | 71篇 |
2016年 | 87篇 |
2015年 | 90篇 |
2014年 | 122篇 |
2013年 | 141篇 |
2012年 | 226篇 |
2011年 | 219篇 |
2010年 | 133篇 |
2009年 | 117篇 |
2008年 | 171篇 |
2007年 | 188篇 |
2006年 | 147篇 |
2005年 | 186篇 |
2004年 | 132篇 |
2003年 | 134篇 |
2002年 | 72篇 |
2001年 | 20篇 |
2000年 | 18篇 |
1999年 | 25篇 |
1998年 | 18篇 |
1997年 | 16篇 |
1996年 | 17篇 |
1995年 | 12篇 |
1994年 | 13篇 |
1993年 | 9篇 |
1992年 | 12篇 |
1991年 | 16篇 |
1990年 | 9篇 |
1989年 | 7篇 |
1988年 | 5篇 |
1987年 | 4篇 |
1986年 | 4篇 |
1985年 | 4篇 |
1984年 | 9篇 |
1983年 | 8篇 |
1982年 | 5篇 |
1981年 | 3篇 |
1979年 | 4篇 |
1978年 | 3篇 |
1975年 | 2篇 |
1974年 | 2篇 |
1965年 | 1篇 |
1898年 | 1篇 |
排序方式: 共有3015条查询结果,搜索用时 187 毫秒
101.
Giulio E. Lancioni Mark F. O’Reilly Nirbhay N. Singh Jeff Sigafoos Francesca Buonocunto Valentina Sacco Jorge Navarro Crocifissa Lanzilotti Marina De Tommaso Marisa Megna Doretta Oliva 《Research in developmental disabilities》2013,34(2):809-816
This study assessed technology-aided programs for helping two post-coma persons, who had emerged from a minimally conscious state and were affected by multiple disabilities, to (a) engage with leisure stimuli and request caregiver's procedures, (b) send out and listen to text messages for communication with distant partners, and (c) combine leisure engagement and procedure requests with text messaging within the same sessions. The program for leisure engagement and procedure requests relied on the use of a portable computer with commercial software, and a microswitch for the participants’ response. The program for text messaging communication involved the use of a portable computer, a GSM modem, a microswitch for the participants’ response, and specifically developed software. Results indicated that the participants were successful at each of the three stages of the study, thus providing relevant evidence concerning performance achievements only minimally documented. The implications of the findings in terms of technology and practical opportunities for post-coma persons with multiple disabilities are discussed. 相似文献
102.
103.
Dinoto Alessandro Rossato Francesco Corradetti Tommaso Gioulis Manuela Marsala Sandro Zambito Ferracci Franco 《Neurological sciences》2022,43(5):2967-2968
Neurological Sciences - 相似文献
104.
Giancarlo Facchini Piergiorgio Di Tullio Milva Battaglia Tommaso Bartalena Cecilia Tetta Costantino Errani Andreas F. Mavrogenis Giuseppe Rossi 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2016,26(3):247-252
Background
To present palliative selective and superselective arterial embolization with N-butyl-cyanoacrylate for cancer patients with spinal metastases.Materials and methods
We studied the files of 164 cancer patients (94 men and 70 women; mean age 57.6 years; range 35–81 years) treated from March 2003 to March 2013 with 178 selective arterial embolization procedures for metastases of the spine from variable primary cancers. We evaluated the technical success of the embolization procedure with post-procedural angiography, the clinical effect in pain relief, need for analgesics and tumor size reduction, and the embolization-related complications.Results
Post-embolization angiography showed complete occlusion of the pathological feeding vessels in all procedures. Pain score and need for analgesics reduced by 50 % in 159 patients (97 %); no response was achieved in five patients with metastases of the sacrum. The mean duration of pain relief was 9.2 months (range 1–12 months). Metastatic tumor size reduced from a mean of 5.5 cm (range 3.5–7.5 cm) pre-embolization to a mean of 4.5 cm (range 3–5 cm) at the 6-month follow-up; the difference was not statistically significant. Ninety-three patients (56.7 %) experienced embolization-related complications the most common being post-embolization syndrome (80 patients, 48.8 %) followed by leg paresthesias (ten patients, 6 %), and rupture of a lumbar artery (one patient, 0.6 %).Conclusion
Selective arterial embolization with N-butyl-cyanoacrylate should be considered for pain palliation of patients with metastases of the spine. However, pain relief is temporary, and complications, although minor may occur.105.
Assessment of functional outcomes of temporalis muscle transfers for patients with longstanding facial paralysis 下载免费PDF全文
106.
Sorrentino R Salameh Z Apicella D Auriemma T Zarone F Apicella A Ferrari M 《The journal of adhesive dentistry》2007,9(6):527-536
PURPOSE: To estimate which combination of restorative materials resulted in the most homogeneous stress and strain distributions in post-and-core treated teeth. MATERIALS AND METHODS: Eight experimental finite element models with different material configurations were simulated; both indirect and direct restorations were considered. An arbitrary load of 50 N was applied on the palatal surface of the crown at a 60-degree angle to the tooth's longitudinal axis to simulate tearing function. RESULTS: In all the models, the values of both strain and stress recorded in the middle third of the buccal aspect of the root surface were off the scale. In contrast, the minimum values were noticed at the level of both the apical portion of the post and the root apex. CONCLUSION: The mechanical properties of the crown and core materials influenced both the position of concentration areas and the level of stress and strain along the dentin/cement/post interfaces. 相似文献
107.
Nedir R Bischof M Pujol O Houriet R Samson J Lombardi T 《The International journal of oral & maxillofacial implants》2007,22(6):1001-1006
This paper reports an implant periapical lesion (IPL) with a previously unreported etiology. The presence of an osteolytic area around the apex and around the middle portion of a stable Straumann hollow-screw implant was found on periapical radiographs 3.5 years after implant placement. Case management involved curettage of the soft tissue surrounding the implant apex as well as resection of the nonosseointegrated portion of the implant. Histopathologic examination revealed a connective fibrous tissue containing a dense chronic inflammatory infiltrate with a foreign-body material. Polarized light microscopy and Fourier transform infrared microspectroscopy identified the foreign-body material as starch particles. Etiology of this IPL was thus related to a foreign-body reaction to starch particles. This exogenous contamination probably originated from starch-coated gloves during the surgical procedure. This case report suggests that IPL may successfully be treated by debridement and implant resection instead of implant removal. Peri-implant apical soft tissue should be systematically submitted for histopathologic examination. 相似文献
108.
Castroflorio T Titolo C Deregibus A Debernardi C Bracco P 《Cranio : the journal of craniomandibular practice》2007,25(3):206-212
The aim of this work was to test the effects of the Function Generator Bite (FGB) on the masticatory muscles of temporomandibular joint dysfunction (TMD) subjects. Two groups were selected for the study. A group of 20 TMD patients (group F) requiring orthodontic treatment and treated with FGB and a group of 10 healthy subjects (group H) were considered. Both groups were evaluated before the therapy began (TO) and then after 18 months of therapy (T1). An electromyographic analysis of the masseter and temporalis anterior muscles and a clinical evaluation according to the Research Diagnostic Criteria for TMD (RDC/TMD) were performed. A statistical difference between the two groups was observed at TO with respect to the activity index. TMD subjects showed a lower value of the index. Further studies are necessary to fully understand the utility of this EMG index as a diagnostic indicator. 相似文献
109.
Nicola Lopomo Cecilia Signorelli Tommaso Bonanzinga Giulio Maria Marcheggiani Muccioli Maria Pia Neri Andrea Visani Maurilio Marcacci Stefano Zaffagnini 《International orthopaedics》2014,38(6):1167-1172
Purpose
Despite the overall success of the surgical anterior cruciate ligament (ACL) reconstruction, some patients still present with instability symptoms even after the surgery, mainly due to the presence of associated lesions. At present, the pivot shift test has been reported to be the benchmark to assess rotatory knee laxity. The purpose of this study was to quantitatively evaluate rotatory knee laxity at time-zero in order to determine whether detected post-reconstruction laxity was predictable by its value measured before the reconstruction, which was hypothized to be influenced by the presence of associated lesions.Methods
Rotatory knee laxity was retrospectively analysed in 42 patients, including two different ACL reconstructions. The maximal anterior displacement and the absolute value of the posterior acceleration reached during the reduction of the tibial lateral compartment were intra-operatively acquired by using a navigation system and identified as discriminating parameters. For each parameter, statistical linear regression analysis (line slope and intercept) was performed between pre- and post-reconstruction values.Results
No statistically significant influence of the initial posterior acceleration on the post-reconstruction outcome was found (line slope, p > 0.05), although a statistically significant line intercept was indeed identified (p < 0.001). A statistically significant influence on the surgery outcome was instead found for the initial value of the anterior tibial displacement (line slope = 0.39, p = 0.004), meaning that, on average, about 40 % of the post-reconstruction lateral compartment displacement could be explained by the corresponding pre-reconstruction value. Both of these findings highlighted the importance of intra-operative quantification of rotatory knee laxity to identify correct indications for the surgery.Conclusions
This study provided important implications for the future possibility of defining a quantifying tool able to assess rotatory knee laxity during ACL reconstruction. This could allow detection of additional injuries to secondary restraints by easily performing rotatory knee laxity tests, which in turn could reduce post-surgical recurrence of knee instability. 相似文献110.
Simone Famularo Matteo Donadon Federica Cipriani Davide P. Bernasconi Giuliano LaBarba Tommaso Dominioni Maurizio Iaria Sarah Molfino Simone Conci Cecilia Ferrari Marco Garatti Antonella Delvecchio Albert Troci Stefan Patauner Silvia Frassani Maurizio Cosimelli Giacomo Zanus Felice Giuliante Valerio De Peppo 《HPB : the official journal of the International Hepato Pancreato Biliary Association》2021,23(6):889-898
BackgroundManagement of recurrence after surgery for hepatocellular carcinoma (rHCC) is still a debate. The aim was to compare the Survival after Recurrence (SAR) of curative (surgery or thermoablation) versus palliative (TACE or Sorafenib) treatments for patients with rHCC.MethodsThis is a multicentric Italian study, which collected data between 2007 and 2018 from 16 centers. Selected patients were then divided according to treatment allocation in Curative (CUR) or Palliative (PAL) Group. Inverse Probability Weighting (IPW) was used to weight the groups.Results1,560 patients were evaluated, of which 421 experienced recurrence and were then eligible: 156 in CUR group and 256 in PAL group. Tumor burden and liver function were weighted by IPW, and two pseudo-population were obtained (CUR = 397.5 and PAL = 415.38). SAR rates at 1, 3 and 5 years were respectively 98.3%, 76.7%, 63.8% for CUR and 91.7%, 64.2% and 48.9% for PAL (p = 0.007). Median DFS was 43 months (95%CI = 32-74) for CUR group, while it was 23 months (95%CI = 18-27) for PAL (p = 0.017). Being treated by palliative approach (HR = 1.75; 95%CI = 1.14–2.67; p = 0.01) and having a median size of the recurrent nodule>5 cm (HR = 1.875; 95%CI = 1.22–2.86; p = 0.004) were the only predictors of mortality after recurrence, while time to recurrence was the only protective factor (HR = 0.616; 95%CI = 0.54–0.69; p<0.001).ConclusionCurative approaches may guarantee long-term survival in case of recurrence. 相似文献