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排序方式: 共有121条查询结果,搜索用时 0 毫秒
101.
Alejandro Chaoul PhD Kathrin Milbury PhD Amy Spelman PhD Karen Basen‐Engquist PhD Martica H. Hall PhD Qi Wei MS Ya‐Chen Tina Shih PhD Banu Arun MD Vicente Valero MD George H. Perkins MD Gildy V. Babiera MD Tenzin Wangyal Geshe Rosalinda Engle MA Carol A. Harrison MEd Yisheng Li PhD Lorenzo Cohen PhD 《Cancer》2018,124(1):36-45
102.
目的 观察藏族原发性高血压家族儿童的空腹胰岛素及胰岛素敏感性状况。方法 1997年 6月至 1998年 8月在拉萨地区横断面整群调查的基础上建立高血压家系图及正常对照家系图 ,入选高血压家系的儿童 4 7例和正常血压家系的儿童 2 1例 ,采用病例 对照的研究方法进行研究。结果 高血压家系的儿童空腹血糖略高于对照组 ,但是未达到差异有显著意义。高血压家系儿童空腹胰岛素水平为 (10± 7.0 )mIU/L显著高于对照组为 (6 .6± 2 .8)mIU/L ,两者之间差异有显著意义 (P <0 .0 5 )。高血压家系儿童的胰岛素敏感指数 (0 .0 36± 0 .0 2 4 )显著低于对照家系儿童 (0 .0 4 6±0 .0 2 2 ) ,经调整体重指数后 ,仍然达临界显著性差异水平。结论 藏族原发性高血压家族的正常血压儿童与对照家系儿童相比已经存在高胰岛素血症 ,并且胰岛素敏感性下降 ,提示这些代谢异常可能与成年后高血压及脂质代谢异常的发生有关。 相似文献
103.
Nirmal K. Thapa Tenzin Karma Wangdi Tshering Dorji Migma Jambay Dorjee Chung K. Marston Alex R. Hoffmaster 《Emerging infectious diseases》2014,20(9):1524-1526
In 2010, we investigated anthrax outbreak in Bhutan. A total of 43 domestic animals died, and cutaneous anthrax developed in 9 persons, and 1 died. All affected persons had contact with the carcasses of infected animals. Comprehensive preparedness and response guidelines are needed to increase public awareness of anthrax in Bhutan. 相似文献
104.
105.
K Ishikawa T Hayashi Y Kohashi S Otani K Kanamasa T Yamakado M Tashi S Osato R Katori 《Japanese circulation journal》1984,48(3):225-232
Left ventricular size is one of the major determinants of myocardial oxygen consumption, therefore if oxygen inhalation reduces myocardial oxygen demand, such might be beneficial in the treatment of acute myocardial infarction. Routine diagnostic biplane left coronary cineangiograms were obtained during air or oxygen breathing in 11 patients with old myocardial infarction or angina pectoris. Coordinates of the points on the left coronary artery were measured and throughout one cardiac cycle frame by frame. The spatial distance (segment length: L) between any two of these points was calculated. Segment length at R wave on the electrocardiogram (LECG R) and minimum value (Lmin) for each segment were calculated. Arterial pO2 was elevated by oxygen breathing from 91 +/- 4 (+/- SE) to 427 +/- 18 mmHg. Left ventricular segment length was significantly reduced by oxygen breathing: LECG R being reduced following oxygen breathing from 62.3 +/- 3.0 to 60.6 +/- 3.0 mm (a decrease of 3.3 +/- 0.8%) and Lmin also being reduced from 55.9 +/- 2.8 to 54.4 +/- 2.8 mm (a decrease of 3.1 +/- 1.0%). These figures indicate that left ventricular size was reduced. Reduction in left ventricular size through oxygen inhalation, by reducing myocardial oxygen demand, should therefore be beneficial in coronary artery disease. 相似文献
106.
We present herein the rare case of a patient who developed peritonitis due to colonic tuberculosis with perforation. The patient
was successfully treated by resectional surgery with delayed restoration of bowel continuity and antitubercular therapy. 相似文献
107.
Tuberculous involvement of the stomach is rare. We report herein the unusual case of a 25-year-old man in whom a benign gastric
ulcer was found along the lesser curvature after he presented with massive upper gastrointestinal bleeding. Histopathological
examination helped to confirm a diagnosis of tuberculosis. The granulomas typical of tuberculosis were caseation with epithelioid
and giant cells. The patient was successfully treated by a combination of appropriate surgical therapy and prompt institution
of antituberculosis medication.
Received: May 14, 1999 / Accepted: March 24, 2000 相似文献
108.
Tandin Dorji In-Kyu Yoon Edward C. Holmes Sonam Wangchuk Tashi Tobgay Ananda Nisalak Piyawan Chinnawirotpisan Kanittha Sangkachantaranon Robert V. Gibbons Richard G. Jarman 《Emerging infectious diseases》2009,15(10):1630-1632
To determine the serotype and genotype of dengue virus (DENV) in Bhutan, we conducted phylogenetic analyses of complete envelope gene sequences. DENV-2 (Cosmopolitan genotype) predominated in 2004, and DENV-3 (genotype III) predominated in 2005–2006; these viruses were imported from India. Primary dengue infections outnumbered secondary infections, suggesting recent emergence. 相似文献
109.
Polymorphisms of renin-angiotensin system in essential hypertension in Chinese Tibetans 总被引:3,自引:0,他引:3
Sun B Dronma T Qin WJ Cui CY Tse D Pingtso T Liu Y Qiu CC 《Biomedical and environmental sciences : BES》2004,17(2):209-216
Objective To evaluate the potential implications of the genetic variability of angiotensin converting enzyme, angiotensinogen and angiotensin Ⅱ type 1 receptor gene for essential hypertension in Tibetan. Methods A case-control study was conducted in 173 hypertensive individuals and 193 individuals with normal blood pressure. Multiple logistic regression analyses were used to estimate the risks of developing hypertension for different genotypes, and haplotype analyses of the angiotensinogen gene were used to determine the association between two-locus angiotensinogen gene polymorphisms and hypertension. Results As to the risk to high blood pressure and high systolic pressure, women with MM genotype were 7.7 (95% CI: 1.3-20.5) and 8.7 (95% CI: 1.8-20A) times higher than those with “IF genotype after adjustment for age and body mass index. Haplotype frequencies for M235T and G-6A were significantly different between hypertensive individuals and controls, which indicated an association of angiotensinogen gene haplotypes with hypertension, and a significant association of 235T/-6A haplotype with hypotensive effect. Condusion Our results suggest that angiotensinogen gene 235MM is a predictor for hypertension development in Tibetan women but not in men, and may exert its hypertensive effect on linkage disequilibrum with a possible function locus of G-6A. 相似文献
110.
Tenzin Choden Rohan Mandaliya Aline Charabaty Mark C Mattar 《World journal of gastrointestinal pharmacology and therapeutics》2018,9(1):1-7
Inflammatory bowel disease has a high prevalence in women of childbearing age and can have a significant impact on pregnancy, from conceiving to carrying the pregnancy. Active disease during pregnancy is known to have negative effects on pregnancy outcomes; therefore, careful monitoring during this period is an important but challenging aspect of care and is crucial as it affects important management decisions. Recent data seems to suggest that endoscopy is a relatively safe procedure during all trimesters of pregnancy. Serum biomarkers such as C-reactive protein and fecal calprotectin are helpful non-invasive markers, but have shown conflicting results for correlation with disease activity in some initial studies. Further work is necessary to establish standard of care monitoring during pregnancy. 相似文献