全文获取类型
收费全文 | 26882篇 |
免费 | 1354篇 |
国内免费 | 102篇 |
专业分类
耳鼻咽喉 | 425篇 |
儿科学 | 505篇 |
妇产科学 | 334篇 |
基础医学 | 3680篇 |
口腔科学 | 681篇 |
临床医学 | 1837篇 |
内科学 | 6680篇 |
皮肤病学 | 662篇 |
神经病学 | 1810篇 |
特种医学 | 1063篇 |
外国民族医学 | 1篇 |
外科学 | 4431篇 |
综合类 | 145篇 |
一般理论 | 2篇 |
预防医学 | 780篇 |
眼科学 | 327篇 |
药学 | 1998篇 |
中国医学 | 79篇 |
肿瘤学 | 2898篇 |
出版年
2022年 | 293篇 |
2021年 | 450篇 |
2020年 | 276篇 |
2019年 | 352篇 |
2018年 | 442篇 |
2017年 | 352篇 |
2016年 | 435篇 |
2015年 | 427篇 |
2014年 | 623篇 |
2013年 | 726篇 |
2012年 | 1176篇 |
2011年 | 1271篇 |
2010年 | 706篇 |
2009年 | 690篇 |
2008年 | 1118篇 |
2007年 | 1313篇 |
2006年 | 1198篇 |
2005年 | 1284篇 |
2004年 | 1216篇 |
2003年 | 1056篇 |
2002年 | 1038篇 |
2001年 | 1032篇 |
2000年 | 965篇 |
1999年 | 902篇 |
1998年 | 314篇 |
1997年 | 223篇 |
1996年 | 243篇 |
1995年 | 193篇 |
1994年 | 167篇 |
1993年 | 188篇 |
1992年 | 629篇 |
1991年 | 546篇 |
1990年 | 533篇 |
1989年 | 529篇 |
1988年 | 516篇 |
1987年 | 484篇 |
1986年 | 459篇 |
1985年 | 428篇 |
1984年 | 311篇 |
1983年 | 256篇 |
1982年 | 160篇 |
1979年 | 246篇 |
1978年 | 157篇 |
1977年 | 184篇 |
1973年 | 177篇 |
1972年 | 186篇 |
1971年 | 190篇 |
1970年 | 172篇 |
1969年 | 186篇 |
1968年 | 170篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
F Suzuki N Miura T Ueda M Minamide K Suzuki H Inomiya T Kotake Y Nishikawa K Yamaguchi H Ito 《Hinyokika kiyo. Acta urologica Japonica》1992,38(2):185-187
A 72-year-old female visited our hospital with the complaint of macroscopic hematuria on Jan. 29, 1990. Cystoscopic examination revealed hematuria flowing out from the left ureteral orifice. A 1 cm mass was found in the left upper calyx by retrograde pyelography (RP). Urine cytology obtained by RP was class IIIb. Later, the mass was found in the left middle calyx by CT. Repeated RP revealed no mass and the wall of the left upper calyx was irregular. Washing cytology from the left renal pelvis was class V. Left total nephroureterectomy was performed on Feb. 2, 1990. Macroscopically, no tumor mass was apparent. Microscopically, transitional cell carcinoma in situ was widely spread from the left renal pelvis to the middle ureter. The preoperative upper calyceal mass was thought to have been a blood clot. At twelve months after the operation, there has been no evidence of tumor recurrence. 相似文献
22.
M Teramachi F Tanaka H Esaki R Inoue M Ito K Kobayashi 《[Zasshi] [Journal]. Nihon Kyōbu Geka Gakkai》1989,37(11):2393-2397
A 14-year-old junior high school boy was admitted to our institute. Previously he had been diagnosed as having peripheral pulmonary stenosis (Gay's classification, type IV) at the age of 2 years and 10 months. On this occasion, however, a diagnosis of supravalvular aortic stenosis was made, with a pressure gradient of about 120 mmHg, and all examinations showed spontaneous remission of peripheral pulmonary stenosis. He underwent a successful standard aortoplasty. This is the first reported case of spontaneous remission of peripheral pulmonary stenosis. 相似文献
23.
A case of generalized eruptive histiocytoma (GEH) was evaluated and examined histopathologically and ultrastructurally. A 24-year-old male had an episode of high fever and drug-induced eruption prior to the appearance of multiple skin lesions. Uniform, red to dark-red papular lesions appeared on his cheeks and then became generalized. The lesions were composed of a massive dermal infiltrate of histiocytes, which had oval nuclei and amphophilic cytoplasm. The cytoplasm contained unique annular structures, myeloid bodies and vacuoles. The specificity of these structures is as yet unknown. Reactive stimulation rather than neoplastic proliferation may be a causative factor in GEH. 相似文献
24.
25.
T Ito S Tanaka K Ban N Sakai H Oshita T Oiwa A Kanno T Kashizuka 《Gan to kagaku ryoho. Cancer & chemotherapy》1987,14(10):2917-2923
During the past 4 years, the performances of various tumor markers such as CA15-3, CEA, ferritin, beta 2-microglobulin and TPA have been evaluated in 78 cases of mammary cancer. The results were categorised according to differences in stages, difference in values from patients with recurrent tumors, the incidence of abnormal values and differences in values before and after surgery. When the incidence of values higher than the cutoff value was determined for each of stage I, II and III + IV, the rates for CEA were 14.3%, 4.9% and 27.8%, respectively, whereas those for TPA were 25.0%, 22.2% and 26.7%, respectively. In addition, for CA15-3, the incidences were 0% in stage I, 5.0% in stage II and 57.1% for combined stages III + IV. The average values for patients with recurrent tumors were 3.2 ng/ml CEA, 194.5 ng/ml ferritin, 316.2 U/l TPA and 81.3 U/ml CA15-3. The rates of abnormal values were 40.0% for CEA, 40.0% for ferritin, 85.7% for TPA and 63.6% for CA15-3. Differences in the values after surgical removal of the tumor were observed with these tumor markers: the CEA value was reduced from 1.6 +/- 1.4 to 1.1 +/- 0.5 (p less than 0.01) and the CA15-3 value from 12.2 +/- 8.4 to 9.3 +/- 4.1 (p less than 0.05), respectively, whereas that for ferritin was conversely increased from 48.9 +/- 48.0 to 74.0 +/- 70.0 (p less than 0.01). However, the values for TPA, despite showing a tendency to decrease, did not show any statistically significant alteration. The fluctuations of these marker levels in patients with recurrent tumors reflects the progress of the disease, with a sudden elevation in values indicating imminent death. The diagnostic significance of these markers is not high, but they are considered to be useful in detecting the progress or condition of a recurrent tumor. 相似文献
26.
Y Ito T Koide S Sakai K Miya K Misawa I Sasaoka 《Hinyokika kiyo. Acta urologica Japonica》1986,32(10):1527-1531
A 50-year-old man with the symptom of anal pain was treated by pelvic exenteration, ileal conduit diversion and artificial anus. The pathologic diagnosis was leiomyosarcoma of the prostate. At 5 months post-operatively, the patient had no evidence of metastasis or recurrence. 相似文献
27.
28.
29.
Yoshitaka Hirooka Yoshikuni Kimura Masatsugu Nozoe Yoji Sagara Koji Ito Kenji Sunagawa 《Hypertension research》2006,29(1):49-56
Amlodipine is a dihydropyridine calcium channel blocker that is widely used for the treatment of hypertensive patients and has an antioxidant effect on vessels in vitro. The aim of the present study was to examine whether treatment with amlodipine reduced oxidative stress in the brains of stroke-prone spontaneously hypertensive rats (SHRSP). The animals received amlodipine, nicardipine or hydralazine for 30 days in their drinking water. Levels of thiobarbituric acid-reactive substances (TBARS) in the brain (cortex, cerebellum, hypothalamus, and brainstem) were measured before and after each treatment. Systolic blood pressure decreased to similar levels in the amlodipine-, nicardipine-, and hydralazine-treated groups. Urinary norepinephrine excretion was significantly reduced in SHRSP after treatment with amlodipine, but not with nicardipine or hydralazine. Levels of TBARS in the cortex, cerebellum, hypothalamus, and brainstem were significantly higher in SHRSP than in Wistar-Kyoto rats (WKY), and were reduced in amlodipine-treated, but not in nicardipine- or hydralazine-treated, SHRSP. Electron spin resonance spectroscopy revealed increased levels of reactive oxygen species in the brains of SHRSP, which were reduced by treatment with amlodipine. Intracisternal infusion of amlodipine also reduced systolic blood pressure, urinary norepinephrine excretion, and the levels of TBARS in the brain. These results suggested that oxidative stress in the brain was enhanced in SHRSP compared with WKY rats. In addition, antihypertensive treatment with amlodipine reduced oxidative stress in all areas of the brain examined and decreased blood pressure without a reflex increase in sympathetic nerve activity in SHRSP. 相似文献
30.
Reviewing the definition of "elderly" 总被引:1,自引:0,他引:1
Hajime Orimo Hideki Ito Takao Suzuki Atsushi Araki Takayuki Hosoi Motoji Sawabe 《Geriatrics & Gerontology International》2006,6(3):149-158
Conventionally, "elderly" has been defined as a chronological age of 65 years old or older, while those from 65 through 74 years old are referred to as "early elderly" and those over 75 years old as "late elderly." However, the evidence on which this definition is based is unknown. We have attempted to review the definition of elderly by analyzing data from long-term longitudinal epidemiological studies, and clinical and pathological studies that have been accumulated at the Tokyo Metropolitan Geriatric Hospital and the Tokyo Metropolitan Institute of Gerontology. Our recommendation might be a starting point in developing a strategy for a successful society by reviewing the definition of elderly based on comprehensive evidence in all aspects of social, cultural and medical sciences. 相似文献