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971.
Q. Dong R. Xiang D.Y. Zhang S. Qin 《Brazilian journal of medical and biological research》2013,46(9):765-770
Oxidative low-density lipoprotein (Ox-LDL) is a key risk factor for the
development of atherosclerosis, and it can stimulate the expression of a variety
of inflammatory signals. As a new and highly sensitive inflammation index, OX40L
may be a key to understanding the mechanisms that regulate interactions between
cells within the vessel wall and inflammatory mediators during the development
of atherosclerosis. To investigate whether Ox-LDL regulates OX40L expression
through an oxidized LDL-1 receptor (LOX-1)-mediated mechanism, we investigated
the effect of different concentrations of Ox-LDL (50, 100, 150 µg/mL) on
endothelial cell proliferation and apoptosis. Stimulation with Ox-LDL increased
OX40L protein 1.44-fold and mRNA 4.0-fold in endothelial cells, and these
effects were inhibited by blocking LOX-1. These results indicate that LOX-1
plays an important role in the chronic inflammatory process in blood vessel
walls. Inhibiting LOX-1 may reduce blood vessel inflammation and provide a
therapeutic option to limit atherosclerosis progression. 相似文献
972.
973.
974.
Xin Zhang Min-Na Han Jing-Hui Dong Xiao-Xi Li Xian-Yun Hu Zhi Wang En-Qiang Qin Jing Li Jun-Yuan Tan Fu-Sheng Wang Lei Huang 《军事医学研究(英文)》2021,8(3):447-449
In 2019,an outbreak of Mycoplasma pneumoniae (M.pneumoniae) occurred at a military academy in China.The attack rate (10.08%,60/595) was significantly different among the units.High-intensity training and crowded environments to which cadets are exposed are the high risk factors for the outbreak of M.pneumoniae.In-time prevention and control measures effectively controlled the spread of the epidemic. 相似文献
975.
976.
977.
The development of Schwann cells, the principal glial cell in the peripheral nervous system, occurs through a series of transitional embryonic and postnatal phases, which are tightly regulated by a number of axonal signals. During the axon ensheathment and myelin growth, the diameter of the axon play an important role in the maturation of Schwann cells. Because of electrospun fibers similar to protein fibers within the native extracellular matrix, the scaffolds are being developed as neural tissue engineering scaffolds. Until now, the correlation between varying diameter of aligned electrospun fibers and Schwann cells maturation has not been investigated. We hypothesize that the different diameter of aligned electrospun fibers may influence the maturation of Schwann cells and may help improve the outcome of cell-based approaches to cure demyelinated lesions or peripheral nerve regeneration. 相似文献
978.
Michael Feyder PhD Carina Plewnia BSc Ori J. Lieberman BSc Giada Spigolon PhD Alessandro Piccin PhD Lidia Urbina BSc Benjamin Dehay PhD Qin Li PhD Per Nilsson PhD Mikael Altun PhD Emanuela Santini PhD David Sulzer PhD Erwan Bezard PhD Anders Borgkvist PhD Gilberto Fisone PhD 《Movement disorders》2021,36(5):1137-1146
979.
Molecular variability of sweet potato chlorotic stunt virus (SPCSV) and five potyviruses infecting sweet potato in China 总被引:3,自引:0,他引:3
Yanhong Qin Zhenchen Zhang Qi Qiao Desheng Zhang Yuting Tian Yongjiang Wang 《Archives of virology》2013,158(2):491-495
To obtain a better understanding of the molecular variation of sweet potato viruses in China, 131 samples were collected from symptomatic sweet potato plants and used for RT-PCR analysis of the heat shock protein 70 (hsp70) gene sequence of sweet potato chlorotic stunt virus (SPCSV) and the coat protein (CP) gene sequences of five potyviruses (SPFMV, SPVC, SPVG, SPLV and SPV2). The hsp70 sequences that were obtained provided evidence for the presence of two distinct strains of SPCSV. Analysis of the CP sequences amplified from the samples indicated that all five potyviruses infect sweet potato in China, and three different strains of SPFMV and two of SPVG were found. 相似文献
980.
Wang Haili Lu Juan Zhao Xia Qin Rongyin Song Kangping Xu Yao Zhang Jun Chen Yingzhu 《Neurological sciences》2021,42(12):4913-4920
Neurological Sciences - Advanced age correlates with higher morbidity and mortality among patients affected with the novel coronavirus disease 2019 (COVID-19). Because systemic inflammation and... 相似文献