全文获取类型
收费全文 | 4034篇 |
免费 | 228篇 |
国内免费 | 15篇 |
专业分类
耳鼻咽喉 | 33篇 |
儿科学 | 191篇 |
妇产科学 | 89篇 |
基础医学 | 530篇 |
口腔科学 | 37篇 |
临床医学 | 289篇 |
内科学 | 808篇 |
皮肤病学 | 66篇 |
神经病学 | 252篇 |
特种医学 | 104篇 |
外科学 | 435篇 |
综合类 | 236篇 |
现状与发展 | 1篇 |
一般理论 | 5篇 |
预防医学 | 339篇 |
眼科学 | 92篇 |
药学 | 331篇 |
中国医学 | 72篇 |
肿瘤学 | 367篇 |
出版年
2023年 | 32篇 |
2022年 | 65篇 |
2021年 | 125篇 |
2020年 | 56篇 |
2019年 | 72篇 |
2018年 | 88篇 |
2017年 | 77篇 |
2016年 | 93篇 |
2015年 | 106篇 |
2014年 | 132篇 |
2013年 | 181篇 |
2012年 | 272篇 |
2011年 | 254篇 |
2010年 | 159篇 |
2009年 | 131篇 |
2008年 | 182篇 |
2007年 | 203篇 |
2006年 | 188篇 |
2005年 | 180篇 |
2004年 | 159篇 |
2003年 | 163篇 |
2002年 | 122篇 |
2001年 | 100篇 |
2000年 | 95篇 |
1999年 | 77篇 |
1998年 | 32篇 |
1997年 | 25篇 |
1996年 | 26篇 |
1994年 | 22篇 |
1993年 | 21篇 |
1992年 | 64篇 |
1991年 | 57篇 |
1990年 | 49篇 |
1989年 | 45篇 |
1988年 | 45篇 |
1987年 | 31篇 |
1986年 | 44篇 |
1985年 | 41篇 |
1984年 | 22篇 |
1983年 | 25篇 |
1979年 | 29篇 |
1977年 | 21篇 |
1976年 | 18篇 |
1975年 | 22篇 |
1974年 | 20篇 |
1973年 | 31篇 |
1972年 | 36篇 |
1971年 | 23篇 |
1970年 | 27篇 |
1968年 | 26篇 |
排序方式: 共有4277条查询结果,搜索用时 0 毫秒
101.
Stroke remains a major cause of morbidity and mortality worldwide. Despite preventive measures, effective management strategies are needed to reduce the morbidity and mortality associated with this devastating condition. While the management of hemorrhagic stroke is mostly limited to supportive care, reperfusion strategies in ischemic stroke have been developed and continue to evolve. Conceptually, the pathophysiology of ischemic stroke is similar to that of acute myocardial infarction and the objective of management is similar (ie, to rapidly restore normal flow to reduce permanent damage). It is, therefore, not surprising that the management of acute ischemic stroke includes intravenous (IV) thrombolysis, the only Food and Drug Administration (FDA)-approved strategy at this point. In addition, there are a myriad of emerging endovascular interventional techniques. We review the current literature and discuss some of the technical aspects of endovascular therapy in the setting of acute ischemic stroke. 相似文献
102.
103.
Sangeeta Bhaskar Sarjana Dutt Rama Mukherjee 《Journal of immunoassay & immunochemistry》2013,34(4):355-375
A very simple and effective procedure which allows simultaneous electroelution of separated proteins from SDS polyacrylamide gel into small quantity of elution buffer is described. Elution parameters have been optimized for maximum possible recovery (50-60%). Protein fractions were collected in physiological buffer and an efficient removal of SDS have been obtained, thus fractions collected were suited for direct testing in cell cultures. Method was used to investigate human T-cell responses to purified secreted M. tuberculosis H37Rv proteins. Eight low molecular weight (M.w. range 10 kD to 25 kD) culture filtrate proteins were purified in quantities, sufficient for immunological characterization. Lymphocyte proliferative responses and cytokine release pattern from tuberculosis patients, healthy contacts and healthy controls were studied on stimulation with purified culture filtrate proteins. Immunologically important M. tuberculosis proteins were identified by using this method. This approach should be applicable to the rapid identification and characterization of any interesting T cell antigen. 相似文献
104.
105.
106.
Douglas PS Carr JJ Cerqueira MD Cummings JE Gerber TC Mukherjee D Taylor AJ 《Journal of nuclear cardiology》2012,19(3):534-550
Technological advances and increased utilization of medical testing and procedures have prompted greater attention to ensuring the patient safety of radiation use in the practice of adult cardiovascular medicine. In response, representatives from cardiovascular imaging societies, private payers, government and nongovernmental agencies, industry, medical physicists, and patient representatives met to develop goals and strategies toward this end; this report provides an overview of the discussions. This expert "think tank" reached consensus on several broad directions including: the need for broad collaboration across a large number of diverse stakeholders; clarification of the relationship between medical radiation and stochastic events; required education of ordering and providing physicians, and creation of a culture of safety; development of infrastructure to support robust dose assessment and longitudinal tracking; continued close attention to patient selection by balancing the benefit of cardiovascular testing and procedures against carefully minimized radiation exposures; collation, dissemination, and implementation of best practices; and robust education, not only across the healthcare community but also to patients, the public, and media. Finally, because patient radiation safety in cardiovascular imaging is complex, any proposed actions need to be carefully vetted (and monitored) for possible unintended consequences. 相似文献
107.
Shivalika Sehgal Lakshmi Shinde Gopinath Madheswaran Paula Mukherjee Pavan Verkicharla Soumya Easwaran Kalika Bandamwar 《Indian journal of ophthalmology》2021,69(4):958
Purpose:The optometry profession has experienced massive changes amid lockdown in COVID 19 pandemic. This study gauges the impact of COVID-19 on optometry education and practices in India.Methods:The impact of COVID-19 among key stakeholders of Indian optometry that included educators, students, and practitioners was surveyed. The content validity of the survey tool was achieved through a focused group discussion with experts.Results:Of the 1408 responses, 118 were educators, 845 were students and 445 were practitioners. Post COVID-19 lock-down, a high percentage of students (96%) and educators (94%) were now using online mode of education to learn and teach. The blended learning methods were reported to be used by 81% of educators. Practical skills were the most difficult to teach by educators and to learn by students. Almost a third of the students were concerned about their internships and job opportunities amid the pandemic. Practitioners felt confident in performing routine eye examinations with personal protective equipment (PPE). Telemedicine was found to be adopted by 55% of the private practitioners and 49% of the eye hospitals.Conclusion:The COVID-19 pandemic has provided an opportunity to reform Indian optometry education through blended learning methods. Optometry practices changed and adapted instantly to the new hygiene norms that have raised the standard of care provided to patients. Telemedicine emerged as a mode of providing care by optometrists. Overall, all key stakeholders of optometry in India were found to have adapted well to the sudden changes due to COVID 19 pandemic. 相似文献
108.
Varicose veins are the most common manifestation of chronic venous insufficiency (CVI) worldwide. They interfere with the patients’ daily activities and hamper their professional endeavors, and therefore need to be addressed at the earliest with the best tools. Eleven patients of varicose veins of the lower limb with below knee perforators underwent subfascial endoscopic perforator surgery (SEPS) from October 2010 to December 2011 in our institute. The procedure was successfully completed in all 11 patients. The mean operating time was 78 min (60–96 min). The results showed a favorable outcome for the patients in terms of faster recovery and less morbidity. 相似文献
109.
Venugopal Jayarama Reddy PhD Sridhar Radhakrishnan PhD Rajeswari Ravichandran M. Eng. Shayanti Mukherjee B. Tech. Ramalingam Balamurugan PhD Subramanian Sundarrajan PhD Seeram Ramakrishna PhD 《Wound repair and regeneration》2013,21(1):1-16
Mimicking porous topography of natural extracellular matrix is advantageous for successful regeneration of damaged tissues or organs. Nanotechnology being one of the most promising and growing technology today shows an extremely huge potential in the field of tissue engineering. Nanofibrous structures that mimic the native extracellular matrix and promote the adhesion of various cells are being developed as tissue‐engineered scaffolds for skin, bone, vasculature, heart, cornea, nervous system, and other tissues. A range of novel biocomposite materials has been developed to enhance the bioactive or therapeutic properties of these nanofibrous scaffolds via surface modifications, including the immobilization of functional cell‐adhesive ligands and bioactive molecules such as drugs, enzymes, and cytokines. In skin tissue engineering, usage of allogeneic skin is avoided to reestablish physiological continuity and also to address the challenge of curing acute and chronic wounds, which remains as the area of exploration with various biomimetic approaches. Two‐dimensional, three‐dimensional scaffolds and stem cells are presently used as dermal regeneration templates for the treatment of full‐thickness skin defects resulting from injuries and severe burns. The present review elaborates specifically on the fabrication of nanofibrous structured strategies for wound dressings, wound healing, and controlled release of growth factors for skin tissue regeneration. 相似文献
110.
Background contextComputed tomography (CT) has become the sole modality of screening for cervical injury in polytrauma because of the high sensitivity, speed, and convenience, thereby eliminating the need for plain radiographs.PurposeWe report two cases of misleading artifactual fracture-subluxation of cervical spine in CT, which could have resulted in needless treatment, and describe its characteristics.Study designCase report and review.MethodsTwo patients who were initially diagnosed with fracture-subluxation on screening CT cervical spine were later noted to have motion artifacts and were reviewed.ResultsThe artifactual nature of the supposed fracture-subluxation was unmasked by the soft-tissue findings of obscuration in sagittal reconstruction and duplication in axial images, along with the presence of double bony margins.ConclusionsMotion artifact in cervical CT screening can lead to a misdiagnosis of fracture subluxation. Duplication of soft tissue is highly suggestive of this motion artifact, and an additional single lateral plain radiograph may avert this pitfall. 相似文献