全文获取类型
收费全文 | 464762篇 |
免费 | 75983篇 |
国内免费 | 27177篇 |
专业分类
耳鼻咽喉 | 5270篇 |
儿科学 | 8810篇 |
妇产科学 | 6454篇 |
基础医学 | 61436篇 |
口腔科学 | 11392篇 |
临床医学 | 66113篇 |
内科学 | 80956篇 |
皮肤病学 | 11326篇 |
神经病学 | 33490篇 |
特种医学 | 16332篇 |
外国民族医学 | 238篇 |
外科学 | 51714篇 |
综合类 | 63421篇 |
现状与发展 | 82篇 |
一般理论 | 52篇 |
预防医学 | 29596篇 |
眼科学 | 12357篇 |
药学 | 46331篇 |
402篇 | |
中国医学 | 23235篇 |
肿瘤学 | 38915篇 |
出版年
2024年 | 1210篇 |
2023年 | 5885篇 |
2022年 | 15363篇 |
2021年 | 20432篇 |
2020年 | 19043篇 |
2019年 | 22586篇 |
2018年 | 22918篇 |
2017年 | 22718篇 |
2016年 | 22497篇 |
2015年 | 28459篇 |
2014年 | 32604篇 |
2013年 | 30693篇 |
2012年 | 32489篇 |
2011年 | 35881篇 |
2010年 | 28749篇 |
2009年 | 20915篇 |
2008年 | 23390篇 |
2007年 | 22105篇 |
2006年 | 21985篇 |
2005年 | 21086篇 |
2004年 | 13934篇 |
2003年 | 12828篇 |
2002年 | 11190篇 |
2001年 | 9898篇 |
2000年 | 10409篇 |
1999年 | 10637篇 |
1998年 | 6283篇 |
1997年 | 6296篇 |
1996年 | 4918篇 |
1995年 | 4462篇 |
1994年 | 3688篇 |
1993年 | 2429篇 |
1992年 | 3305篇 |
1991年 | 2841篇 |
1990年 | 2436篇 |
1989年 | 2140篇 |
1988年 | 1825篇 |
1987年 | 1612篇 |
1986年 | 1291篇 |
1985年 | 1087篇 |
1984年 | 662篇 |
1983年 | 447篇 |
1982年 | 290篇 |
1981年 | 301篇 |
1980年 | 231篇 |
1979年 | 272篇 |
1978年 | 131篇 |
1977年 | 124篇 |
1974年 | 129篇 |
1973年 | 115篇 |
排序方式: 共有10000条查询结果,搜索用时 8 毫秒
11.
Weina Cheng Yazhi Wang Jingxian Liu Xiaofei Li Ming Yu Cancan Duan Liu Liu Jianyong Zhang 《Journal of applied toxicology : JAT》2022,42(6):970-980
Cantharidin (CTD) is an effective antitumor agent. However, it exhibits significant hepatotoxicity, the mechanism of which remains unclear. In this study, biochemical and histopathological analyses complemented with ultra-high-performance liquid chromatography–tandem mass spectrometry (UHPLC-MS/MS)-based targeted metabolomic analysis of bile acids (BAs) were employed to investigate CTD-induced hepatotoxicity in rats. Sixteen male and female Sprague–Dawley rats were randomly divided into two groups: control and CTD (1.0 mg/kg) groups. Serum and liver samples were collected after 28 days of intervention. Biochemical, histopathological, and BA metabolomic analyses were performed for all samples. Further, the key biomarkers of CTD-induced hepatotoxicity were identified via multivariate and metabolic pathway analyses. In addition, metabolite–gene–enzyme network and Kyoto Encyclopedia of Genes and Genomes pathway analyses were used to identify the signaling pathways related to CTD-induced hepatotoxicity. The results revealed significantly increased levels of biochemical indices (alanine aminotransferase, aspartate aminotransferase, and total bile acid). Histopathological analysis revealed that the hepatocytes were damaged. Further, 20 endogenous BAs were quantitated via UHPLC-MS/MS, and multivariate and metabolic pathway analyses of BAs revealed that hyocholic acid, cholic acid, and chenodeoxycholic acid were the key biomarkers of CTD-induced hepatotoxicity. Meanwhile, primary and secondary BA biosynthesis and taurine and hypotaurine metabolism were found to be associated with the mechanism by which CTD induced hepatotoxicity in rats. This study provides useful insights for research on the mechanism of CTD-induced hepatotoxicity. 相似文献
12.
Feng Song Li Ruipiao Wang Zhiying 《Odontology / the Society of the Nippon Dental University》2022,110(3):508-522
Odontology - To investigate the characterization and function of a novel porous osteogenic material (PLLA / DDM) containing polylactic acid and demineralized dentin matrix. The surface morphology... 相似文献
13.
14.
15.
Forgiveness has been found one substantial element in the recovery for women survivors from intimate partner violence following the termination of the abusive relationship. To further investigate the details of forgiveness in this specific context, the present study explored the process of forgiveness using grounded theory. In-depth and semi-structured interviews were conducted with 25 Chinese women survivors of IPV. The findings suggest that forgiveness is a strength-based process including empowerment, transformation, and integration phases. In the empowerment phase, survivors obtain strength at the intrapersonal, behavioural, and interpersonal levels. In the transformation phase, survivors complete cognitive transformation for their IPV experiences and emotional transformation towards former partners. In the integration phase, survivors—now freed from the past—reflect upon and apply the changes they have undergone. Two trajectories in the process were found. One trajectory is going through stages sequentially and the other trajectory is experiencing back and forth between empowerment and transformation stages before moving into the integration stage. The study's findings broaden our knowledge of the strength-based forgiveness process that women survivors of IPV undergo during recovery. Practitioners and policymakers could develop programmes and policies that support forgiveness by holistically facilitating their recovery and empowerment like assistance in dealing with life difficulties and promoting their reconnection with social networks. To improve the transferability and validity of the findings, the forgiveness of survivors of IPV could be explored in a diverse sample (e.g., survivors with low educational background or live in the rural area). 相似文献
16.
17.
18.
Evelyne Harkemanne Jean‐Louis Dargent Pierre‐Paul Roquet‐Gravy Audrey Bulinckx 《Pediatric dermatology》2019,36(3):365-367
We report a case of benign lymphoplasmacytic plaque (LPP) in a child. These asymptomatic erythematous papulonodular lesions are an emerging clinicopathological entity. Herein, we describe a previously unreported site for LPP lesions, namely, the volar wrist and the distal ipsilateral palm. 相似文献
19.
20.