全文获取类型
收费全文 | 7482篇 |
免费 | 323篇 |
国内免费 | 31篇 |
专业分类
耳鼻咽喉 | 65篇 |
儿科学 | 199篇 |
妇产科学 | 110篇 |
基础医学 | 810篇 |
口腔科学 | 137篇 |
临床医学 | 407篇 |
内科学 | 1768篇 |
皮肤病学 | 109篇 |
神经病学 | 682篇 |
特种医学 | 247篇 |
外科学 | 1303篇 |
综合类 | 27篇 |
预防医学 | 239篇 |
眼科学 | 217篇 |
药学 | 511篇 |
中国医学 | 19篇 |
肿瘤学 | 986篇 |
出版年
2023年 | 55篇 |
2022年 | 78篇 |
2021年 | 120篇 |
2020年 | 85篇 |
2019年 | 128篇 |
2018年 | 127篇 |
2017年 | 105篇 |
2016年 | 149篇 |
2015年 | 141篇 |
2014年 | 176篇 |
2013年 | 214篇 |
2012年 | 339篇 |
2011年 | 383篇 |
2010年 | 236篇 |
2009年 | 187篇 |
2008年 | 377篇 |
2007年 | 364篇 |
2006年 | 427篇 |
2005年 | 448篇 |
2004年 | 464篇 |
2003年 | 459篇 |
2002年 | 426篇 |
2001年 | 176篇 |
2000年 | 168篇 |
1999年 | 160篇 |
1998年 | 127篇 |
1997年 | 90篇 |
1996年 | 90篇 |
1995年 | 70篇 |
1994年 | 64篇 |
1993年 | 66篇 |
1992年 | 136篇 |
1991年 | 114篇 |
1990年 | 126篇 |
1989年 | 97篇 |
1988年 | 90篇 |
1987年 | 80篇 |
1986年 | 77篇 |
1985年 | 59篇 |
1984年 | 61篇 |
1983年 | 59篇 |
1982年 | 42篇 |
1981年 | 26篇 |
1980年 | 27篇 |
1979年 | 38篇 |
1978年 | 28篇 |
1977年 | 32篇 |
1976年 | 27篇 |
1973年 | 24篇 |
1971年 | 24篇 |
排序方式: 共有7836条查询结果,搜索用时 31 毫秒
81.
A single-strip miniaturized paper chromatographic method (Mini-PC) was developed using 80%-90% acetone solvent for rapid purity-control of 99mTc-radiopharmaceuticals. Routine 99mTc-radiopharmaceuticals (eight kinds of "kit" made agents) and diluted agents (in which radiochemical impurities might be formed) were analyzed by Mini-PC and other methods. This showed that, compared with the other methods, the Mini-PC technique is useful for the simple and rapid routine analysis of radiochemical impurities of "kit" made 99mTc-radiopharmaceuticals. 相似文献
82.
Shigeru Sanada Atsushi Ando Itsuko Ando Tatsunosuke Hiraki Kinichi Hisada 《European journal of nuclear medicine and molecular imaging》1986,12(8):390-393
A single-strip miniaturized paper chromatographic method (Mini-PC) was developed using 80%–90% acetone solvent for rapid purity-control of 99mTc-radiopharmaceuticals. Routine 99mTc-radiopharmaceuticals (eight kinds of kit made agents) and diluted agents (in which radiochemical impurities might be formed) were analyzed by Mini-PC and other methods. This showed that, compared with the other methods, the Mini-PC technique is useful for the simple and rapid routine analysis of radiochemical impurities of kit made 99mTc-radiopharmaceuticals. 相似文献
83.
Hiroji Shinkawa Shogo Tanaka Shigekazu Takemura Ryosuke Amano Kenjiro Kimura Masahiko Kinoshita Kanae Takahashi Shuichiro Matsuzaki Shoji Kubo 《Surgery》2021,169(4):922-928
BackgroundExtrahepatic recurrence and early intrahepatic recurrence of hepatocellular carcinoma after hepatic resection are indicative of poor prognoses. We aimed to develop nomograms to predict extrahepatic recurrence and early intrahepatic recurrence after hepatic resection.MethodsThe participants of this study were 1,206 patients who underwent initial and curative hepatic resection for hepatocellular carcinoma. Multivariate logistic regression analyses using the Akaike information criterion were used to construct nomograms to predict extrahepatic recurrence and early intrahepatic recurrence (within 1 year of surgery) at the first recurrence sites after hepatic resection. Performance of each nomogram was evaluated by calibration plots with bootstrapping.ResultsExtrahepatic recurrence was identified in 95 patients (7.9%) and early intrahepatic recurrence in 296 patients (24.5%). Three predictive factors, α-fetoprotein >200 ng/mL, tumor size (3–5 cm or >5 cm vs ≤3 cm), and image-diagnosed venous invasion by computed tomography, were adopted in the final model of the extrahepatic recurrence nomogram with a concordance index of 0.75. Tumor size and 2 additional predictors (ie, multiple tumors and image-diagnosed portal invasion) were adopted in the final model of the early intrahepatic recurrence nomogram with a concordance index of 0.67. The calibration plots showed good agreement between the nomogram predictions of extrahepatic recurrence and early intrahepatic recurrence and the actual observations of extrahepatic recurrence and early intrahepatic recurrence, respectively.ConclusionWe have developed reliable nomograms to predict extrahepatic recurrence and early intrahepatic recurrence of hepatocellular carcinoma after hepatic resection. These are useful for the diagnostic prediction of extrahepatic recurrence and early intrahepatic recurrence and could guide the surgeon’s selection of treatment strategies for hepatocellular carcinoma patients. 相似文献
84.
Kanako Omata Noriki Okada Go Miyahara Yuta Hirata Yukihiro Sanada Yasuharu Onishi Shinya Fukuda Hideki Kumagai Alan Kawarai Lefor Yasunaru Sakuma Naohiro Sata 《Transplantation proceedings》2021,53(4):1317-1321
BackgroundMyotubular myopathy is a rare disease sometimes accompanied by peliosis hepatis, a leading cause of fatal liver hemorrhage.Case ReportWe present a case of a 2-year-old boy with myotubular myopathy who developed liver hemorrhage because of peliosis hepatis and was successfully treated with living-donor liver transplant. The patient initially presented with fever, anemia, and liver dysfunction. A computed tomographic scan revealed hemorrhages in the liver, and the patient underwent hepatic artery embolization twice. After the second embolization, multiple peliosis hepatis cavities appeared in the left lobe of the liver that had increased in size. Therefore, the patient underwent ABO-incompatible living-donor liver transplant using a lateral segment graft from his father. The patient developed severe septic shock with an unknown focus on postoperative day 18, which resolved with antibiotic therapy. On postoperative day 62, he was discharged. Fourteen months after undergoing living-donor liver transplant, the patient showed no recurrence of peliosis hepatis.ConclusionsAlthough the long-term prognosis of peliosis hepatis due to myotubular myopathy after living-donor liver transplant remains unclear, liver transplant may be a curative treatment for patients with myotubular myopathy who have uncontrollable peliosis hepatis. 相似文献
85.
Wada Takehiko Ishimoto Takuji Nakaya Izaya Kawaguchi Takehiko Sofue Tadashi Shimizu Sayaka Kurita Noriaki Sasaki Sho Nishiwaki Hiroki Koizumi Masahiro Saito Shoji Nishibori Nobuhiro Oe Yuji Yoshida Mai Miyaoka Yoshitaka Akiyama Shin’ichi Itano Yuya Okazaki Masaki Ozeki Takaya Ichikawa Daisuke Oguchi Hideyo Kohsaka Satoshi Kosaka Shiho Kataoka Yuki Shima Hideaki Shirai Sayuri Sugiyama Kazuhiro Suzuki Tomo Son Daisuke Tanaka Tomomi Nango Eishu Niihata Kakuya Nishijima Yoko Nozu Kandai Hasegawa Midori Miyata Rei Yazawa Masahiko Yamamoto Yoshihiro Yamamoto Ryohei Shibagaki Yugo Furuichi Kengo Okada Hirokazu Narita Ichiei 《Clinical and experimental nephrology》2021,25(12):1277-1285
Clinical and Experimental Nephrology - 相似文献
86.
87.
Bibek Dutta Taichi Asami Tohru Imatomi Kento Igarashi Kento Nagata Tomomi Watanabe-Asaka Takako Yasuda Shoji Oda Manfred Shartl Hiroshi Mitani 《Journal of radiation research》2021,62(1):12
Transgenic expression in medaka of the Xiphophorus oncogene xmrk, under a pigment cell specific mitf promoter, induces hyperpigmentation and pigment cell tumors. In this study, we crossed the Hd-rR and HNI inbred strains because complete genome information is readily available for molecular and genetic analysis. We prepared an Hd-rR (p53+/−, p53−/−) and Hd-rR HNI hybrid (p53+/−) fish-based xmrk model system to study the progression of pigment cells from hyperpigmentation to malignant tumors on different genetic backgrounds. In all strains examined, most of the initial hyperpigmentation occurred in the posterior region. On the Hd-rR background, mitf:xmrk-induced tumorigenesis was less frequent in p53+/− fish than in p53−/− fish. The incidence of hyperpigmentation was more frequent in Hd-rR/HNI hybrids than in Hd-rR homozygotes; however, the frequency of malignant tumors was low, which suggested the presence of a tumor suppressor in HNI genetic background fish. The effects on tumorigenesis in xmrk-transgenic immature medaka of a single 1.3 Gy irradiation was assessed by quantifying tumor progression over 4 consecutive months. The results demonstrate that irradiation has a different level of suppressive effect on the frequency of hyperpigmentation in purebred Hd-rR compared with hybrids. 相似文献
88.
89.
90.
Pharmaceutical Research - 相似文献