全文获取类型
收费全文 | 161篇 |
免费 | 10篇 |
国内免费 | 5篇 |
专业分类
儿科学 | 1篇 |
妇产科学 | 5篇 |
基础医学 | 31篇 |
口腔科学 | 6篇 |
临床医学 | 14篇 |
内科学 | 36篇 |
皮肤病学 | 6篇 |
神经病学 | 6篇 |
特种医学 | 7篇 |
外科学 | 20篇 |
预防医学 | 3篇 |
眼科学 | 6篇 |
药学 | 19篇 |
中国医学 | 1篇 |
肿瘤学 | 15篇 |
出版年
2024年 | 1篇 |
2023年 | 3篇 |
2022年 | 13篇 |
2021年 | 19篇 |
2020年 | 15篇 |
2019年 | 15篇 |
2018年 | 14篇 |
2017年 | 8篇 |
2016年 | 5篇 |
2015年 | 6篇 |
2014年 | 7篇 |
2013年 | 4篇 |
2012年 | 16篇 |
2011年 | 8篇 |
2010年 | 6篇 |
2009年 | 1篇 |
2008年 | 3篇 |
2007年 | 3篇 |
2006年 | 4篇 |
2005年 | 1篇 |
2004年 | 2篇 |
2003年 | 2篇 |
2002年 | 3篇 |
2001年 | 2篇 |
1997年 | 1篇 |
1990年 | 1篇 |
1989年 | 2篇 |
1987年 | 1篇 |
1983年 | 1篇 |
1982年 | 2篇 |
1981年 | 1篇 |
1975年 | 1篇 |
1974年 | 2篇 |
1972年 | 1篇 |
1966年 | 1篇 |
1963年 | 1篇 |
排序方式: 共有176条查询结果,搜索用时 15 毫秒
171.
E.E. Abbas N. Afioni M.A. Bakr A. Donia E. Khidir A.H. Mitwali A. Pingle A. Roshdy B. Shaibani D.S. Shaker M. Solieman 《Transplantation proceedings》2004,36(6):1805
Recombinant human erythropoietin has proved to be effective to treat anemia of end-stage renal disease (ESRD). The aim of this study was to assess the efficacy and safety profile of Epotin, a rHuEPO produced in the Middle East. One hundred thirty patients with Hct ≤ 27%; Hb ≤ 9 g/dL maintained on hemodialysis thrice weekly from 19centers in eight countries in the Middle East were recruited into this 13-week study. Depleted iron stores (TSTAT <20% and/or Serum ferritin < 100 μg/dL) were replenished prior to initiation of Epotin therapy, which was delivered intravenously in a dose of 150 U/kg body weight/week in three equal doses postdialysis and titrated according to hemoglobin (Hb) and hematocrit (Hct) response. Efficacy was assessed in terms of Hb/Hct response. Epotin raised the mean Hb level from 7.7 (± 1.2) g/dL to 12.0 (± 1.7) g/dL and Hct from 22.7 (± 4.1) % to 36.2 (± 5.7) % by week 13. The increase started to show significance at week 3. Targeting an absolute increase in Hb of 2.5 g/dL (Hct 7.5%) over a 13-week period, the success rate was of <85.71%. Segregating patients into subgroups of men and women and chronic ESRD versus recent ESRD failed to reveal a significant differences in either the severity of the anemia or the response to Epotin. Side effects were similar to other erythropoietins; no dropouts were reported. In conclusion, Epotin is effective to treat anemia in patients on maintenance hemodialysis with an acceptable safety profile. No difference in response was observed between men and women, nor between patients with different levels of chronicity of ESRD. 相似文献
172.
Vaginal eversion was observed in Argas (Chiropteragas) boueti. During eversion, both cervical and vestibular parts of the vagina are fully everted so that the former is anteriorly oriented, whereas the latter occupies the posterior end of the everted organ. The histology of normal and everted vaginas is described and correlated with its functional and biological significance. Vaginal eversion most likely occurs while the tick is ovipositing and may be involved in the wax-coating process of eggs by Gene's organ. 相似文献
173.
Matthew Tsang MSc Michelle Le BSc Feras M. Ghazawi MD PhD Janelle Cyr MSc Akram Alakel BSc Elham Rahme PhD François Lagacé BSc Elena Netchiporouk MD MSc Linda Moreau MD Andrei Zubarev MSc Osama Roshdy MD Steven J. Glassman MD Denis Sasseville MD Gizelle Popradi MD Ivan V. Litvinov MD PhD 《Cancer》2019,125(14):2435-2444
174.
Abdel-Rahman N Zekri Somaya El Deeb Abeer A Bahnassy Abeer M Badr Mona S Abdellateif Gamal Esmat Hosny Salama Marwa Mohanad Ahmed Esam El-dien Shimaa Rabah Assmaa Abd Elkader 《World journal of gastroenterology : WJG》2018,24(11):1228-1238
AIM To assess the levels of different immune modulators in patients with hepatocellular carcinoma(HCC),in relation to other hepatic diseases.METHODS Eighty-eight patients were included in the current study and represented patients with HCC(20),liver cirrhosis(28) and chronic hepatitis(CH;25),and normal controls(NC;15).Peripheral blood was isolated for immunophenotyping of active myeloid dendritic cells(m DCs;CD1 c and CD40),mature inactive myeloid cells(CD1 c and HLA),active plasmacytoid cells(p DCs;CD303 and CD40),mature inactive p DCs(CD30 and HLA),active natural killer(NK) cells(CD56 and CD161),active NK cells(CD56 and CD314) and inactive NK cells(CD56 and CD158) was done by flow cytometry.Serum levels of interleukin(IL)-2,IL-10,IL-12,IL-1β,interferon(IFN)-α,IFN-γ and tumor necrosis factor(TNF)-αR2 were assessed by ELISA.RESULTS Active m DCs(CD1 C+/CD40+) and inactive m DCs(CD1 c+/HLA+) were significantly decreased in HCC patients in relation to NC(P 0.001).CD40+ expression on active p DCs was decreased in HCC patients(P 0.001),and its level was not significantly changed among other groups.Inactive p DCs(CD303+/HLA+),inactive NKs(CD56+/CD158+) and active NKs(CD56+/CD161+) were not statistically changed among the four groups studied;however,the latter was increased in CH(P 0.05).NKG2 D was statistically decreased in HCC,CH and cirrhosis(P 0.001),and it was not expressed in 63%(12/20) of HCC patients.There was significant decrease of IL-2,IFN-α and IFN-γ(P 0.001),and a significant increase in IL-10,IL-1β,and TNF-αR2(P 0.01,P 0.001 and P 0.001;respectively) in HCC patients.There was inverted correlation between IL-12 and IL-1β in HCC(r =-0.565,P 0.01),with a strong correlation between p DCs(CD303+/CD40+) and NKs(CD56+/CD161+;r = 0.512,P 0.05) as well as inactive m DCs(CD1 c+/HLA+) and inactive NK cells(CD56+/CD158+;r = 0.945,P 0.001).CONCLUSION NKG2 D,CD40,IL-2 and IL-10 are important modulators in the development and progression of HCC. 相似文献
175.
A I Gadallah G M Khalil W H Dees M A Roshdy A S Marzouk A J Main 《Journal of medical entomology》1989,26(4):360-367
The biochemical effects of juvenile hormone III (JH III) on developing embryos from treated female Argas (Persicargas) arboreus Kaiser, Hoogstraal and Kohls were examined. Exogenous JH III resulted in a decrease in total proteins (P less than 0.001) only during the first 2 d of embryogenesis. There was no significant difference (P greater than 0.05) between RNA and DNA content in eggs from control and JH III-treated females. No significant difference (P greater than 0.05) was observed between control and JH III eggs in their lipid or phospholipid contents throughout embryogenesis. A total of 14-17 protein bands and 6-8 glycoprotein bands were separated by electrophoresis during embryogenesis of A. arboreus with some differences in mobility ratio between bands from control and JH III eggs. Differences in activity and isozyme patterns of malic acid, lactic acid, glucose 6-phosphate dehydrogenase, acid phosphatase, and alkaline phosphatase were not observed during embryogenesis of control and JH III-treated A. arboreus. Differences were observed in esterase activity. 相似文献
176.
Ahmed F. Ahmed Nabila N. El-Maraghy Rasha H. Abdel Ghaney Shimaa M. Elshazly 《Saudi Journal Of Gastroenterology》2012,18(3):182-187