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61.
Washio M Saitoh S Arai Y Takagi S Oonishi H Isobe T Takeuchi H Oohata J Mori M Shimamoto K 《Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics》2005,42(2):221-228
OBJECTIVE: The present study was conducted in order to investigate risk factors for heavy burden of family caregivers. STUDY DESIGN: Cross-sectional study. PARTICIPANTS: 51 pairs of the frail elderly and their family caregivers in one town in Hokkaido. RESULTS: Compared to those with a lighter burden, family caregivers with heavier burden looked after the frail elderly with more behavior disturbances due to dementia. They cared for the elderly longer and had less time to go out without accompanying their charges than less burdened caregivers. On the other hand, the elderly had similar activities of daily living and degree of need of care between the two groups. In addition, physical caring time did not differ between the two groups. These findings suggest that the psychological burden may be more important than the physical burden. In addition, caregivers used only 30-40% of services they had the right to use with long-term care insurance. These findings suggest that more convenient services for users should be provided. 相似文献
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Naomi Sato Yasuhiro Nakamura Kentaro Takanami Yoshikiyo Ono Kei Omata Ryo Morimoto Fumitoshi Satoh Kazue Ise Shigeyuki Yamada Atsuko Kasajima Fumiyoshi Fujishima Mika Watanabe Yoichi Arai Hironobu Sasano 《Endocrine pathology》2014,25(4):410-415
Usually, benign tumors are not associated with an increased F-18 fluorodeoxyglucose (F-18 FDG) uptake on positron emission tomography (PET), although some exceptions have been reported in adrenal neoplasms. We present a rare case of adrenocortical oncocytoma associated with markedly increased FDG uptake, demonstrating a maximum standardized uptake value of 46.8. Histological examination demonstrated diffuse proliferation of tumor cells with eosinophilic and granular cytoplasm that were diffusely immunopositive for mitochondria and glucose transport protein 1, with focal and weak immunopositivity for 3β-hydroxysteroid dehydrogenase. Ultrastructural examination also revealed abundant mitochondria in the tumor cells. The tumor was diagnosed as adrenocortical oncocytoma and was considered benign according to Lin-Weiss-Bisceglia criteria. Diagnosis of adrenocortical oncocytoma can pose difficulties during both preoperative radiological and postoperative histopathological investigations. 相似文献
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Muraki S Akune T Oka H Ishimoto Y Nagata K Yoshida M Tokimura F Nakamura K Kawaguchi H Yoshimura N 《Arthritis and rheumatism》2012,64(5):1447-1456
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Ebara S Song SN Mizuta H Ito Y Hasegawa K Kamata T Matsumura-Nishikawa T Ogawa T Soneda J Yoshizaki K 《International journal of hematology》2012,95(2):198-203
Dysregulated overproduction of interleukin-6 (IL-6) from activated B cells in affected lymph nodes has been implicated in
the pathogenesis of multicentric Castleman’s disease (MCD), a rare lymphoproliferative disorder accompanied by systemic manifestations.
We here report the case of a 32-year-old female presenting with MCD associated with a dermoid cyst in the pelvic cavity. The
co-occurrence of MCD and dermoid cyst has not been reported before. Immunohistochemical analysis of the tissue sections showed
IL-6 production in CD68-positive macrophage cells, which had infiltrated the dermoid cyst. Removal of the cyst resulted in
partial improvement in systemic symptoms accompanied by a decrease in serum IL-6, while complete improvement was obtained
by treatment with an anti-IL-6 receptor antibody following resection of the dermoid cyst. To the best of our knowledge, this
is the first study to provide evidence of IL-6 production by CD68+ cells in a dermoid cyst involved in MCD. 相似文献
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Jun Takahashi Hirokazu Kobayashi Shinji Wakabayashi Masao Deguchi Hidehiro Ito Yuji Mogami Hirotaka Tanikawa Hiroyuki Nakagawa Hideki Moriya Ryohei Ashizawa Kenji Takahara Hisatoshi Kinoshita Yutaka Tateiwa Hiromichi Misawa Takahiro Tsutsumimoto Taku Nakakohji Yohei Yuzawa Akihito Sawaumi Yohei Hidai Satoshi Matsuda Isao Nakamura Shigeyuki Toba Mikio Kamimura Takeshi Nakane Hiroki Hirabayashi Hiroyuki Hashidate Nobuhide Ogihara Keijiro Mukaiyama Hiroyuki Kato Kuniyoshi Ohtsuka 《Journal of orthopaedic science》2013,18(2):208-215