全文获取类型
收费全文 | 38160篇 |
免费 | 2031篇 |
国内免费 | 137篇 |
专业分类
耳鼻咽喉 | 568篇 |
儿科学 | 952篇 |
妇产科学 | 893篇 |
基础医学 | 5020篇 |
口腔科学 | 2753篇 |
临床医学 | 2397篇 |
内科学 | 8846篇 |
皮肤病学 | 1087篇 |
神经病学 | 3541篇 |
特种医学 | 851篇 |
外国民族医学 | 1篇 |
外科学 | 4437篇 |
综合类 | 210篇 |
一般理论 | 7篇 |
预防医学 | 3461篇 |
眼科学 | 919篇 |
药学 | 2836篇 |
中国医学 | 273篇 |
肿瘤学 | 1276篇 |
出版年
2023年 | 318篇 |
2022年 | 712篇 |
2021年 | 1394篇 |
2020年 | 768篇 |
2019年 | 1163篇 |
2018年 | 1476篇 |
2017年 | 941篇 |
2016年 | 1016篇 |
2015年 | 1142篇 |
2014年 | 1555篇 |
2013年 | 1961篇 |
2012年 | 2990篇 |
2011年 | 3210篇 |
2010年 | 1689篇 |
2009年 | 1331篇 |
2008年 | 2359篇 |
2007年 | 2277篇 |
2006年 | 2058篇 |
2005年 | 1848篇 |
2004年 | 1731篇 |
2003年 | 1414篇 |
2002年 | 1321篇 |
2001年 | 829篇 |
2000年 | 843篇 |
1999年 | 662篇 |
1998年 | 210篇 |
1997年 | 133篇 |
1996年 | 127篇 |
1995年 | 105篇 |
1994年 | 108篇 |
1993年 | 77篇 |
1992年 | 242篇 |
1991年 | 247篇 |
1990年 | 227篇 |
1989年 | 178篇 |
1988年 | 173篇 |
1987年 | 162篇 |
1986年 | 126篇 |
1985年 | 118篇 |
1984年 | 96篇 |
1983年 | 90篇 |
1981年 | 46篇 |
1980年 | 41篇 |
1979年 | 77篇 |
1978年 | 61篇 |
1975年 | 43篇 |
1973年 | 45篇 |
1972年 | 41篇 |
1971年 | 52篇 |
1967年 | 64篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
91.
J M Barbero A I Ezpeleta M López Gil J L Barroso F García-Cosío 《Revista espa?ola de cardiología》1991,44(7):485-487
A 76-year-old woman with an inferior wall myocardial infarction, with right ventricular involvement, developed severe arterial hypoxemia with neurological involvement. Pulmonary edema or embolism and chronic obstructive pulmonary disease were ruled-out, and a right-to-left shunt was demonstrated by contrast echocardiography at the level of the foramen ovale. After inotropic support and oxygen supplementation, the patient recovered, although with significant neurological sequelae. No focal lesions were detected in the central nervous system by computerized tomography. Hypoxemia improved, coinciding with the disappearance of right-to-left shunt by contrast echocardiography. 相似文献
92.
A Esteller M D Torres M Gomez-Bautista E L Mari?o C Fernandez-Lastra R Jimenez 《European journal of drug metabolism and pharmacokinetics》1990,15(1):7-14
We studied the hepatic handling of bromosulfophthalein in healthy rabbits with hepatic coccidiosis 28 days after an experimental infection with sporulated oocysts of Eimeria stiedai, an experimental model of liver disease histopathologically resembling primary biliary cirrhosis in man. A pharmacokinetic study of the results was performed following a multicompartmental model with 7 transfer constants to describe the physiological disposition of the dye. The study showed that the plasma disappearance, distribution volume (Vi), hepatic biotransformation and the biliary and urinary elimination of conjugated (BSPc) and unconjugated (BSPu) bromosulfophthalein were markedly altered. Whereas Vi and urinary excretion of the dye were significantly increased, the hepatic clearance, biotransformation and biliary excretion of BSPc and BSPu were drastically reduced in infected rabbits. Satisfactory agreement was obtained between the experimental and estimated data, particularly those relating to biotransformation clearance and biliary and urinary excretion of the dye. These results demonstrate that severe liver disease in rabbits with histopathological liver alterations resembling several hepatic dysfunctions in man markedly reduce hepatic uptake, metabolism and biliary excretion of a xenobiotic such as BSP. 相似文献
93.
M Abbes C Boursault D Conso E Roméo 《Annales de chirurgie plastique et esthétique》1992,37(4):394-401
Based on a series of 220 cases of reconstruction (63 cases) or correction (67 cases) of the nipple-areolar complex and various extramammary procedures (tattoo scar revision, lips, eyebrows, eyelashes) (90 cases), the authors present their 2-year experience of medical dermography in a cancer centre. Dermography allows breast reconstruction to be completed in a large number of patients who had initially refused to complete their reconstruction. This minimally aggressive outpatient technique which reconstitutes the areolo-nipple complex with sufficient quality, is now part of reconstruction protocols and is gradually replacing surgical techniques. 相似文献
94.
F Ledesma Casta?o S Echevarria Vierna J L Lozano Polo R Oloriz Rivas C Alvarez Moreno F Pons Romero 《European journal of clinical nutrition》1992,46(7):527-533
Interleukin-1 (IL-1) is a cytokine produced by the macrophage-monocyte system that has important effects on immunological responses and inflammatory reactions. Several clinical studies have shown that severe protein energy malnutrition adversely effects cell-mediated immune responses and the functional state of macrophages. The objective of this study was to analyse IL-1 production by adherent cells stimulated in vitro with lipopolysaccharide B (LPS) from patients with alcoholic cirrhosis of the liver and its possible relationship with nutritional states. Forty-five patients with alcoholic cirrhosis and 28 healthy donors were investigated. A combined index of nine anthropometric and biochemical parameters was used to evaluate nutritional status of cirrhotic patients, allowing a distinction to be made between those patients with acceptable nutrition (group I: 40%), those with slight malnutrition (group II: 37.7%), and those with severe malnutrition (group III: 22.3%). IL-1 activity was significantly lower in the cirrhosis patients than in the controls (P less than 0.001). This activity also was significantly lower in samples obtained from cirrhotics with severe malnutrition than in those with acceptable nutrition (P less than 0.05); the combined index and the sole anthropometric index gave the same results, suggesting that malnutrition may play a role in the immunoregulatory disturbances in the pathogenesis of alcoholic liver disease. 相似文献
95.
96.
Egidio L. Romano res Soyano Ramón F. Montaño Murray Ratcliffe Marilyn Olson Guillermo Suarez Nelly Martínez and Geoffrey Worstey 《Vox sanguinis》1994,66(3):194-199
Thirteen infants, 10 with A-O and 3 with B-O hemolytic disease of the newborn (ABO-HDN), were treated with synthetic A or B blood group trisaccharides (ATS, BTS) which cause dissociation of maternal antibody bound to infant red cells. The clinical outcome was compared with that of a control group of 21 infants treated with phototherapy during the preceding year. Exchange transfusion was required in 2 out of 13 infants in the experimental group and in 7 in the control group. A randomized prospective controlled study is necessary to confirm these results. 相似文献
97.
Sympathetic skin response in scleroderma. 总被引:1,自引:0,他引:1
M Raszewa I Hausmanowa-Petrusewicz M B?aszczyk S Jab?ońska 《Electromyography and clinical neurophysiology》1991,31(8):467-472
Examination of the sympathetic skin response (SSR) was performed in 32 patients with systemic sclerosis, morphea and mixed connective tissue disease displaying scleroderma-like features. The control group consisted of 26 healthy subjects and 12 patients with other skin diseases and asymmetrical cutaneous changes. Right and left median and tibial nerves were stimulated successively and the responses were recorded from the palms and soles simultaneously. SSR abnormalities (delayed latency, decrease and/or asymmetry of amplitude, absent response) were observed in 68.8% of the patients, most frequently in linear scleroderma. An amplitude asymmetry of the responses from upper extremities was the most characteristic pattern of abnormalities. There was no correlation between the SSR and the localization, degree and character (inclurated oedema, atrophy, sclerosis) of skin changes, the duration of the disease, symptoms of the disorder of the autonomic nervous system symptoms (vasomotor and/or sudomotor) and the changes in capillaroscopy. All patients with slow motor conduction and sensor conduction velocities (MCV and SCV) had lower SSR amplitude and the patients with prolonged skin sensory chronaxy had more often delayed latency. The results revealed presence of disturbances of the autonomic nervous system in all varieties of scleroderma, both systemic and localized forms, even without any other signs of autonomic dysfunction. 相似文献
98.
99.
Abstract
Background. To avoid the adverse consequences of abdominal compartment syndrome and to reduce the high mortality the celiotomy wound
in patients with abdominal sepsis was closed without tension using prosthetic mesh. This produces a semiopen situation that
permits staged reinterventions together with the functional reconstitution of the continuity of the abdominal wall.
Material and Methods. Twenty-five patients with intra-abdominal sepsis of various causes were evaluated retrospectively to assess the results of
semiopen management of the septic abdomen and reoperations on demand in severe peritonitis. All of the patients were in a
state of neglected peritonitis, and had at least one failing organ system. The Mannheim Peritonitis Index (MPI) scoring system
was used for stratification of abdominal sepsis.
Results. The mean MPI score of 25 patients was 24, ranging 10 to 33. Eight (32%) patients were reexplored (MPI=21). There were overall
9 (36%) complications in patients with mean MPI score of 23. Six (24%) mesh-related complications (infection and enterocutaneous
fistulas) developed (MPI=19). The mean MPI score of patients without complications was 24. Four (16%) patients died with index
MPI score of 26 due to fulminant hepatitis, myocardial infarction, and multiple organ failure. The admission period averaged
63 days.
Conclusions. In 25 critically ill patients with abdominal sepsis the mortality was lower than expected, relative to heterogeneous data
from the literature; also, major complications occurred less frequently although the mean MPI score was high. The authors
conclude that this approach is a reliable contribution to the complex treatment of these patients.
Electronic Publication 相似文献
100.
Aida Brand?o Sónia Magalh?es Adelino Correia 《Revista portuguesa de cardiologia》2004,23(7-8):993-999
Congenitally corrected transposition of the great arteries, L-TGA, is a rare abnormality accounting for less than 0.5% of clinically apparent congenital heart disease. Age at time of diagnosis and survival rate are variable and depend mostly on associated anomalies. The authors present a clinical case of a twenty-four-year-old woman in whom, in a routine echocardiogram, congenitally corrected transposition of the great arteries and aortic coarctation were diagnosed, an unusual association. They describe the results of complementary exams (echocardiography, chest X-ray, electrocardiogram and cardiac angiography) that they believe to be useful for the correct diagnosis of this clinical situation. Additionally, the authors make a brief review of the literature relevant to the case. 相似文献