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排序方式: 共有911条查询结果,搜索用时 31 毫秒
71.
Ibrahim Tuncer Sinan Bilgin Mehmet
zgür Zengin Mehmet Serhat Mangan Abdullah Karaca Cezmi Doan Esat nar 《Eye (London, England)》2021,35(2):672
BackgroundTo evaluate the effect of brimonidine tartrate 0.15% ophthalmic solution on pupil size under scotopic condition and upper eyelid position.MethodsThis study comprised 72 eyes of 36 healthy subjects. A single drop of brimonidine tartrate 0.15% ophthalmic solution was instilled in the right eye and artificial tear was instilled in the left eye. Pupil size was measured using an infra-red pupillometer under scotopic condition before and at 30 min, 2, 4, 6, 8 and 10 h after instillation. Measurement of margin reflex distance 1 (MRD1) was performed using a millimetre ruler before and after at 10 min after instillation.ResultsThe mean age of the subjects was 32.19 ± 11.43 years (range 10–52 years), 17 were female and 19 were male. Before brimonidine instillation, the mean pupil size was 6.09 ± 1.03 mm in the brimonidine eyes and 6.06 ± 1.04 mm in the control eyes. There was a significant decrease in mean pupil size at 30 min (4.45 ± 1.04), 2 h (4.49 ± 1.06), 4 h (4.59 ± 1.06), 6 h (4.89 ± 1.06) and 8 h (5.38 ± 1.02) after instillation compared to before in brimonidine eyes (p < 0.001 for all). There was a significant miosis continued for at least 6 h (5.95 ± 1.03) in control eyes (p < 0.001). There was no significant change in MRD1, before and after instillation both in brimonidine and control eyes.ConclusionsBrimonidine tartrate 0.15% had a significant miosis under scotopic condition for at least 8 h after instillation and had a significant miosis on the untreated eye for at least 6 h.Subject terms: Outcomes research, Eye manifestations 相似文献
72.
Symptoms, therapy, and outcome of 49 cases of anaphylactic reaction are presented. Epinephrine (0.5-2.0 mg) did not produce any circulatory improvement but induced severe dysrhythmias and even ventricular fibrillation. Neither epinephrine nor prednisolone (2 g) prevented shock development, neurologic sequelae, or fatal outcome. Rapid infusion of 2000 ml 50% colloid (dextran 70 or starch, m.w. 450,000) with 50% Ringer's lactate, however, reliably restored circulation within 30 min. If elevated, airway resistance dropped in conjunction with colloid administration rather than with any other drug. Impairment of the pulmonary circulation is found to be the initial feature of anaphylaxis, manifested by a rise in pulmonary vascular resistance; then stroke volume and systemic blood pressure fall as left heart filling is reduced. Many findings indicate a high blood viscosity with resulting capillary occlusion: rapid clotting; low levels of factors I, II, V, VIII, and X; low plasma protein, which may be only 50% of its normal value; thrombocytopenia; and aggregation of white blood cells with fibrin in small lung vessels. Blood and plasma vanish from the circulation and appear to be sequestered in the pulmonary capillaries as the initial response to the antigen; later, the whole body is affected. Congestion and pain in the lymph nodes indicate that the lymphatic system may also become involved. On the basis of hemoconcentration, a blood volume deficiency in the range of 30% has been calculated.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
73.
Akif Serhat Gur Bulent Unal Gretchen Ahrendt Michael L. Gimbel Oguz Kayiran Ronald Johnson Marguerite Bonaventura Atilla Soran 《Central European Journal of Medicine》2009,4(1):65-70
Breast cancer related upper extremity lymphedema (BCRL) reduces the quality of life of those who have had surgery for breast
cancer. The aim of this study is to evaluate the risk factors for BCRL and determine whether immediate autologous tissue breast
reconstruction is one of them. A case control study was conducted comparing patients with BCRL (n=97) to surgically treated
breast cancer patients without BCRL (control, n=126). The groups were matched for age, type of breast surgery and radiation
therapy. Postoperative upper extremity infection, body mass index (BMI), occupation (level of hand-use), and immediate autologous
tissue breast reconstruction were investigated as a risk factor of BCRL. Mastectomy was performed on 47.6 % (n=60) and 37.2%
(n=36) of patients in the control and the BCRL groups, respectively. Eight patients (13.3%) had immediate autologous tissue
breast reconstruction in the control mastectomy group. Six of 36 BCRL patients (16.7%) underwent mastectomy with immediate
autologous tissue breast reconstruction. There was no significant difference between groups with respect to incidence or method
of immediate reconstruction (p=0.65). Patient occupation (level of hand use) was found to be positively correlated to development
of BCRL (p=0.0001). Upper extremity infection rate was 22.7% in the BCRL group and 4.0% in the controls (p=0.0001). The mean
BMI in the control and BCRL groups 26.8 kg/m2 and 29.1kg/m2, respectively (p=0.003). In conclusion, in this study characteristics positively associated with development of BCRL included
occupation, infection, and increased BMI. Immediate reconstruction of the breast was not found as a risk factor for BCRL.
However larger studies are needed, to further evaluate the effect of breast reconstruction on BCRL. 相似文献
74.
75.
In 30 septic, edematous intensive care patients a polyneuropathy occurred during treatment of peritonitis, pancreatitis, adult respiratory distress syndrome, or bronchopneumonia; 28 patients developed a complete tetraplegia. We believe this neuropathy to be an important cause of weaning failure. All patients had received parenteral or enteral nutrition with 240-800 g carbohydrate per day. Clinical data indicate that impairment of carbohydrate metabolism was the essential cause of the polyneuropathy. In 14 patients carbohydrate administration was continued; 13 died without neuromuscular recovery. In 16 patients carbohydrate nutrition was reduced to 100-250 g per day after the occurrence of tetraplegia; 13 of these made a full neurologic recovery. 相似文献
76.
Fatih Irmak Sevgi Kurt Yazar Serhat Selami Şirvan Ayşim Özağarı Ayşin Karasoy Yeşilada 《Journal of plastic surgery and hand surgery》2018,52(4):229-233
Introduction: Burn healing is a complicated process and very few treatments can positively alter its effects. The aim of this study was to investigate the effects Salvia miltiorrhiza (SM -Danshen), a traditional Chinese medicine, on burn wound healing.Material and methods: Twenty rats were included in this study and divided into two groups. 3?×?2?cm wide burn areas were created in the dorsal skin of all the animals with thermal contact. Intraoral 1?ml/day saline and 1?g/kg/day SM were given in control and experiment groups, respectively. Fourteen days following the burn injury burn zones were evaluated with indocyanine green-SPY imaging device, and multiple samples were collected for histopathological evaluation. Standard photographs were taken for the evaluation of necrotic skin areas.Results: Neovascularization was increased in the SM group when compared with the control group (p?=?0.0406). SPY studies revealed a meaningful increase in the tissue perfusion in the SM group (p?=?0.0286). The average amount of necrotic area in the control and experiment group on the postoperative 14th day was 71.6% (±16.51) and 42.5% (±10.64) respectively (p?=?0.0002).Conclusion: Our study shows that SM can decrease the amount of necrosis in burn wounds by increasing tissue perfusion and neovascularization. 相似文献
77.
Serhat Erol Fatma Arslan Ciftci Aydin Ciledag Akin Kaya Ozlem Ozdemir Kumbasar 《Advances in medical sciences》2018,63(2):237-241
Purpose
Immunocompromised patients with latent tuberculosis infection (LTBI) are at high risk of progression to active tuberculosis. Detection and treatment of LTBI in this group of patients are very important to control active tuberculosis. Tuberculin skin test (TST) and interferon gamma release assays (IGRAs) are two methods for detection of LTBI. Diagnostic agreement between two tests are poor especially in Bacillus Calmette-Guérin (BCG) vaccinated immunocompromised patients. In this study, we tried to figure out if the use of a higher cut-off for TST increases diagnostic agreement with IGRAs and TST specificity and or not.Materials/Methods
In this retrospective study, BCG vaccinated solid organ transplantation (SOT) candidates and patients scheduled for anti-tumor necrosis factor-alpha (anti- TNFα) treatment patients who underwent both TST and IGRAs between 2011 and 2017 were enrolled in the study. Diagnostic agreement between the two tests was assessed for 5, 10, 15 mm cut-off values for all participants, SOT candidates and anti- TNFα treatment subgroups separately.Results
Fifty female and 55 male total 105 patients were included. In the anti- TNFα treatment group 92.8% of the patients were receiving at least one immunosuppressive drug. For all participants kappa (κ) values were 0.303, 0.370, 0.321 respectively for 5, 10 and 15 mm cut-offs. For SOT candidates κ values were 0.488, 0.422, 0.288 respectively. For anti- TNFα treatment group κ values were 0.235, 0.332, 0.275 respectively.Conclusions
In BCG vaccinated immunocompromised patients, the agreement between TST and QFT-GIT was poor regardless of cut-off value. And increasing the cut-off does not improve agreement. 相似文献78.
79.
80.
Bone wax is primarily used in case of bleeding of the diploic vessels of the bones in surgical procedures. It is useful in neurosurgical procedures because of its inert, nonreactive characteristics. Bone wax is safe material and its use rarely leads to complications but there may be complications of over use. It can cause direct pressure of neural tissue as a mass, simulating tumour with the symptoms and on MRI. In the present case the authors evaluated the signs and symptoms, diagnosis, surgical treatment, and outcome in a patient with an unusual sequestered mass simulating a spinal tumour or another space-occupying lesion on preoperative MR imaging. A 64-year-old was woman admitted to the Neurosurgery Clinic with a 10 year history of low back pain, 1-year history of gait disorder, leg weakness, paraparesis, and 1-month history of urinary incontinence and weight loss. T1- weighted sagittal MRI showed the L3 hemilaminectomy, discectomy defect, heterogeneous hyperintense extradural mass and spinal stenosis extending from L2. A hypointense mass relative to the spinal structures was detected in T2- weighted axial MR images.The provisional diagnosis of a cauda equina syndrome and intra- or extradural spinal tumour was made. The patient underwent an L2 total laminectomy. In our case the fragment was seen in the epidural space, under the lamina of L2. The histopathology showed granulation tissue, inflammatory cells, macrophages and multinuclear giant cells. Postoperatively the patient's neurological findings recovered quickly and she began to walk more comfortably. 相似文献