全文获取类型
收费全文 | 3440篇 |
免费 | 238篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 20篇 |
儿科学 | 125篇 |
妇产科学 | 106篇 |
基础医学 | 416篇 |
口腔科学 | 67篇 |
临床医学 | 346篇 |
内科学 | 806篇 |
皮肤病学 | 81篇 |
神经病学 | 198篇 |
特种医学 | 76篇 |
外科学 | 444篇 |
综合类 | 79篇 |
一般理论 | 5篇 |
预防医学 | 252篇 |
眼科学 | 95篇 |
药学 | 309篇 |
中国医学 | 19篇 |
肿瘤学 | 246篇 |
出版年
2024年 | 5篇 |
2023年 | 42篇 |
2022年 | 118篇 |
2021年 | 171篇 |
2020年 | 91篇 |
2019年 | 139篇 |
2018年 | 183篇 |
2017年 | 95篇 |
2016年 | 107篇 |
2015年 | 102篇 |
2014年 | 147篇 |
2013年 | 211篇 |
2012年 | 288篇 |
2011年 | 234篇 |
2010年 | 153篇 |
2009年 | 123篇 |
2008年 | 182篇 |
2007年 | 199篇 |
2006年 | 201篇 |
2005年 | 157篇 |
2004年 | 138篇 |
2003年 | 106篇 |
2002年 | 90篇 |
2001年 | 37篇 |
2000年 | 44篇 |
1999年 | 34篇 |
1998年 | 14篇 |
1997年 | 15篇 |
1996年 | 14篇 |
1995年 | 6篇 |
1994年 | 9篇 |
1993年 | 8篇 |
1992年 | 20篇 |
1991年 | 18篇 |
1990年 | 19篇 |
1989年 | 9篇 |
1988年 | 16篇 |
1987年 | 16篇 |
1986年 | 16篇 |
1985年 | 16篇 |
1984年 | 6篇 |
1983年 | 10篇 |
1981年 | 10篇 |
1980年 | 12篇 |
1979年 | 9篇 |
1976年 | 4篇 |
1973年 | 8篇 |
1972年 | 4篇 |
1971年 | 6篇 |
1968年 | 4篇 |
排序方式: 共有3690条查询结果,搜索用时 15 毫秒
41.
42.
43.
44.
45.
46.
47.
Abdul Qayyum Rana Abdul Rehman M. Qureshi Faiha Fareez Mohammad A. Rana 《The International journal of neuroscience》2016,126(8):734-738
Anxiety and depression are common in Parkinson's disease (PD) patients, yet their prevalence and severity compared to individuals without PD requires more research. Moreover, it has never been compared across different ethnic groups. The objective of this study was to close that gap in the literature by exploring the caseness and severity of anxiety and depression in PD patients of different ethnicities compared to controls without PD. It was found that caseness and severity of anxiety and depression are higher in individuals with PD compared to controls. Furthermore, the caseness and severity of anxiety and depression do not vary significantly among ethnic groups. Finally, depression caseness was not predicted by age, gender, disease duration, restless legs syndrome prevalence, Hoehn and Yahr (H&Y) score nor Unified Parkinson's disease rating scale part III (UPDRS-III) score. Anxiety caseness was predicted by gender, with females 2.7 times more likely to have anxiety caseness than males. Overall, our study suggests that treatment plans should be individualized based on prevalence and severity of the two conditions in individuals with PD rather than generalize treatment for specific ethnic groups. 相似文献
48.
Fahad A. Almugbel Narhari Timilshina Naser AlQurini Allison Loucks Rana Jin Arielle Berger Lindy Romanovsky Martine Puts Shabbir M.H. Alibhai 《Journal of Geriatric Oncology》2021,12(5):786-792
Background: The Vulnerable Elders Survey (VES-13) is commonly used to identify older patients who may benefit from Comprehensive Geriatric Assessment (CGA) prior to cancer treatment. The optimal cut point of the VES-13 to identify those whose final oncologic treatment plan would change after CGA is unclear. We hypothesized that patients with high positive VES-13 scores (7–10)have a higher likelihood of a change in treatment compared to low positive scores (3–6).Methods: Retrospective review of a customized database of all patients seen for pre-treatment assessment in an academic geriatric oncology clinic from June 2015 to June 2019. Various VES-13 cut points were analyzed to identify those individuals whose treatment was modified after CGA. Area under the curve (AUC) was calculated and subgroups of patients treated locally or systemically were also examined to determine if performance varied by treatment modality.Results: We included 386 patients with mean age 81, 58% males. Gastrointestinal cancer was the most common site (31%) and 60% were planned to receive curative treatment. The final treatment plan was modified in 59% overall, with 52.7% modified with VES-13 scores 7–10, 50.8% with scores 3–6 and 28.1% with scores <3 (P = 0.002). VES-13 performance in predicting treatment modification was similar for cut points 3 (AUC 0.58), 4 (0.59), 5 (0.59), and 6 (0.59) and in those considering local treatment vs. chemotherapy.Conclusions: A positive VES-13 score was associated with final oncologic treatment plan modification. A high positive score was not superior to the conventional cut point of ≥3. 相似文献
49.
50.
Julian Jakob Roman von Wyl Odile Stalder Mark J. Pletcher Eric Vittinghoff Kali Tal Jamal S. Rana Stephen Sidney Jared P. Reis Reto Auer 《The American journal of medicine》2021,134(6):777-787.e9
BackgroundLong-term cardiovascular health effects of marijuana are understudied. Future cardiovascular disease is often indicated by subclinical atherosclerosis for which carotid intima-media thickness is an established parameter.MethodsUsing the data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, a cohort of 5115 Black and white women and men at Year 20 visit, we studied the association between carotid intima-media thickness in midlife and lifetime exposure to marijuana (1 marijuana year = 365 days of use) and tobacco smoking (1 pack-year = 20 cigarettes/day for 365 days). We measured carotid intima-media thickness by ultrasound and defined high carotid intima-media thickness at the threshold of the 75th percentile of all examined participants. We fit logistic regression models stratified by tobacco smoking exposure, adjusting for demographics, cardiovascular risk factors, and other drug exposures.ResultsData was complete for 3257 participants; 2722 (84%) reported ever marijuana use; 374 (11%) were current users; 1539 (47%) reported ever tobacco smoking; 610 (19%) were current smokers. Multivariable adjusted models showed no association between cumulative marijuana exposure and high carotid intima-media thickness in never or ever tobacco smokers, odds ratio (OR) 0.87 (95% confidence interval [CI]: 0.63-1.21) at 1 marijuana-year among never smokers and OR 1.11 (95% CI: 0.85-1.45) among ever tobacco smokers. Cumulative exposure to tobacco was strongly associated with high carotid intima-media thickness, OR 1.88 (95%CI: 1.20-2.94) for 20 pack-years of exposure.ConclusionsThis study adds to the growing body of evidence that there might be no association between the average population level of marijuana use and subclinical atherosclerosis. 相似文献