针刀治疗第三腰椎横突综合征:随机对照观察

目的:探讨针刀对第三腰椎横突综合征的治疗效果。方法:将第三腰椎横突综合征患者180例按区组随机法分为针刀治疗组、阻滞组及针刺对照组,分别进行针刀、阻滞及针刺治疗。治疗前、后分别按“腰椎疾患治疗成绩评分表”评分,对测评结果进行统计学分析。结果:治疗前后成绩评分,针刀组治疗前(9.6±2.7)分,治疗后(23.0±5.7)分,改善指数0.56±0.61;阻滞组治疗前(9.9±2.8)分,治疗后(15.1±7.1)分,改善指数0.33±0.27;针刺组治疗前(9.7±2.9)分,治疗后(13.2±6.5)分,改善指数0.24±0.21。3组治疗前后评分,针刀治疗组优于阻滞及针刺对照组(P<0.001,t=18.32,5.65,4.21);3组疗效比较,针刀治疗组明显优于阻滞及针刺对照组(P<0.01,χ2=38.1,41.1);3组治疗后评分均比治疗前分值差异有显著性意义(P<0.001,t=6.39,11.85)。结论:与阻滞、针刺治疗组相比,针刀是保守治疗第三腰椎横突综合征值得采用的有效方法之一。     

霍夫曼虚拟内疚理论:内疚研究的心理学进展

目的介绍内疚研究的心理学进展,并对其理论意义进行评价.资料来源应用计算机检索Psychological数据库1980-01/2003-12期间关于霍夫曼以及与内疚、移情、道德的相关文献,检索词"Hoffman"、"guilt"、"empathy"、"moral",限定文章语言种类为"Ehglish".资料选择在所查找到的文献中,选择霍夫曼的专著和文章,以及其他心理学家的著述中涉及霍夫曼内疚和虚拟内疚研究的文献.排除重复研究类文章.资料提炼围绕内疚和虚拟内疚,对所选文献进行提炼,共得到有关霍夫曼虚拟内疚研究的书籍和文献9部(篇).资料综合9部(篇)文献包括综述1篇,专著8部.其中1部专著解释了虚拟内疚的涵义及类型,1篇综述和3部专著阐述了虚拟内疚发生机制,5部专著分析了虚拟内疚的影响因素,1部专著对霍夫曼的理论意义进行了评价.结论霍夫曼的理论认为虚拟内疚是尽管人们实际上并没有做伤害他人的事情,或所作所为并没有违犯公认的社会道德规范,但如果他们以为自己做了错事或与他人所受到的伤害有间接关系,也会感到内疚而自责.其分为四大类关系性内疚,责任性内疚,发展性内疚,幸存性内疚.并认为虚拟内疚是移情性悲伤与认知归因相结合的产物,主要受既往经验、移情能力、道德水平和关系程度影响.霍夫曼关于虚拟内疚的研究,不仅拓展了内疚研究的领域、丰富了内疚研究的内容,而且从新的角度揭示了道德情感在个体道德发展中的自我调节和自我教育作用.     

能谱CT成像评价末端回肠炎

目的 观察末端回肠炎宝石能谱CT成像（GSI）表现，并与常规CT小肠造影（CTE）比较，分析其对末端回肠炎的诊断价值。方法 回顾性分析120例疑诊末端回肠疾病患者，结肠镜及病理检查显示72例末端回肠炎，6例回盲部息肉或肿瘤样病变，30例回肠克罗恩病及7例回肠肠结核，5例未见明显异常。其中70例接受常规CTE，50例接受GSI，比较其影像学表现。分析2种方法检出末端回肠炎的结果与病理结果的一致性，比较其敏感度和特异度，绘制ROC曲线，并分析其诊断效能。结果 相比常规CTE，GSI低keV单能量图像显示病灶较清晰，相应能谱曲线及碘基图能清晰区分病变肠壁、正常肠壁、肠腔液体及邻近脂肪组织；动、静脉期末端回肠炎病变肠壁碘浓度分别为（10.90±0.55）及（14.33±0.75）μg/cm³。常规CTE及GSI检测末端回肠炎与病理结果的一致性分别为差及较高（Kappa=0.35、0.72，P=0.16、<0.01）；GSI检出末端回肠炎的敏感度、特异度（86.21%、85.71%）均高于常规CTE（65.12%、51.85%，χ²=3.97、6.10，P均<0.05）。GSI检出末端回肠炎的AUC（0.86）高于常规CTE（0.57，Z=2.42，P=0.02）。结论 GSI能清晰显示末端回肠炎病灶，对末端回肠炎有较高诊断效能。     

疗治结合型军队疗养院护理人力资源的管理

目的探索疗治结合型军队疗养院高效、合理利用护理人力资源的管理方法。方法在军队编制体制调整改革和疗养事业的迅速发展的形势下，挖掘内部潜力，采取双向性选择方式，增进工作，加强内部交流，合理使用有限资源。结果拓宽了疗养服务范围，不同程度地满足了各类型疗养员疗养保健需求，达到了疗养和医疗护理技术建设的协调发展。结论医院管理者对护理工作的重视、加强护理队伍素质建设、科学的配置人力资源，对疗治结合型军队疗养院护理人力资源的科学管理起到重要作用。     

腹腔镜下子宫切除后女性激素的观察

目的　研究使用腹腔镜切除子宫对病人卵巢激素的影响。方法　分别在手术前后对 2 0例腹腔镜子宫切除病人抽取血清 ,用化学发光法检测LH、FSH、E2 、P的水平。对照组为 2 0例开腹切除子宫病人。结果　在腹腔镜组E2 、P、LH、FSH值低于对照组 ,但统计学处理无明显差异 (P >0 .0 5 )。结论　结果显示腹腔镜子宫切除术与开腹子宫切除术一样 ,近期对保留卵巢的功能无明显影响     

Mitochondrial pathway is responsible for aging-related increase of tubular cell apoptosis in renal ischemia/reperfusion injury

Aging-related changes of tubular cell apoptosis and its mechanisms in renal ischemia/reperfusion (I/R) injury are unclear. In the present study, aged (27-month-old) and young (3-month-old) Wistar rats were used to investigate aging-related tubular cell apoptosis in the setting of renal I/R injury. The renal I/R model was induced by clamping bilateral renal arteries for 30 minutes followed by reperfusion for 18 hours. Cyclosporine A (CsA, 2 mg/kg) or mycophenolate mofetil (MMF, 20 mg/kg/d) was used before ischemia. Age-matched sham-operated rats served as controls. We found that tubular cell apoptosis increased more significantly in aged rats than in young rats after renal I/R. More pronounced increases of Bax/Bcl-2 ratio, cytosolic cytochrome c, and caspase-9, which are involved in mitochondria-mediated apoptosis, were found in aged rats than in young rats, and were associated with a more pronounced decrease in superoxide dismutase activity and increase of malondialdehyde content. However, increases of tumor necrosis factor-alpha and caspase-8, two components of death receptor-mediated apoptosis, showed no aging-related differences. Interfering mitochondria and death receptor pathways with CsA and MMF, respectively, reduced the apoptosis in both age groups, whereas CsA was more effective in aged rats. Our results have demonstrated that there was an aging-related increase of tubular cell apoptosis in the renal I/R model, which may be, at least partly, due to an enhanced mitochondrial pathway resulting possibly from increased oxidative stress.     

异搏定、尼卡地平对原发性高血压患者离体血管平滑肌细胞内钙的干预研究

作者采用原发性高血压患者的离体动脉血管 ,并分离、培养动脉平滑肌细胞 ,观察了异搏定、尼卡地平对人动脉平滑肌细胞内钙的影响。由于原发性高血压患者动脉血管平滑肌细胞内钙的跨膜流动和细胞内释放机制尚不清楚 ,作者试图得到异搏定、尼卡地平对人离体动脉平滑肌细胞内钙释放和转运的直接证据。结果如下 :(1)原发性高血压患者动脉平滑肌细胞内总钙比正常血压组高 ,并与细胞内游离钙明显相关 ;(2 )两个钙通道拮抗剂均能显著减少两组的细胞内钙。异搏定显著减少4 5Ca2 的跨膜内流 ,尼卡地平主要是阻止细胞内钙的释放     

老年性单纯收缩期高血压患者的左心结构和功能

用彩色多普勒超声心动图仪测量63例单纯收缩期高血压(ISH)的左室结构和功能,发现ISH的左室重量指数142±23.9 g/m~2大于对照组122.5±25.6 g/m~2(P<0.05);ISH的二尖瓣血流心房收缩速度59±10.9 cm·s~(-1)高于对照组50±12.6 cm·s~(-1)(P<0.05)。结果表明,ISH患者存在着左室肥厚和舒张功能异常,有效降低ISH的收缩压,可望逆转左室肥厚和异常的舒张功能,减少ISH患者的心血管并发症的发生和死亡。     

Effect of Nimesulide on proliferation and apoptosis of human hepatoma SMMC—7721 cells

AIM:Cyclooxygenase-2(COX-2)has been suggested to be associated with carcinogenesis.We sought to investigate the effect of the selective COX-2 inhibitor,Nimesulide on proliferation and apoptosis of SMMC-7721 human hepatoma cells.METHODS:This study was carried out on the culture of hepatic carcinoma SMMC-7721 cell line Various concentrations of Nimesulide(0,200μmol/L,300μmol/L,400μmol/L)were added and incubated.Cell proliferation was detected with MTT colorimetric assay,cell proliferation was detected with MTT colorimetric assay,cell apoptosis by electron microscopy,flow cytometry and TUNEL.RESULTS:Nimesulide could significantly inhibit SMMC-7721 cells proliferation dose-dependent and in a dependent manner compared with that of the controla group.The duration lowerst inhibition rate produced by Nimesulide in SMMC-7721 cells was 19.06%,the highest inhibition rate was 58.49%,After incubation with Nimesulide for 72h,the most highest apotosis rate and apoptosis index of SMMC-7721 cells comparing with those of the control were 21.20%&#177;1.62%,vs2.24%&#177;0.26%and 21.23&#177;1.78vs2.01&#177;0.23(P&lt;0.05).CONCLUSION:The selective COX-2 inhibitor,Nimesulide can inhibit the proliferation of SMMC-7721 cells and increase apoptosis rate and apoptosis index of SMMC-7721 cells,The apoptosis rate and the apoptosis index are dose-dependent.Under electron microscope SMMC-7721 cells incubated with 300 μmol and 400μmol Nimesulide show apoptotic characteristics With the clarification of the mechanism of selective COX-2 inhibitors,Thtese COX-2 selective inhibitors can become the choice of prevention and treatment of cancers.     

人体蠕形螨致病性与致病因素的探讨

对新疆人体蠕形螨进行了流行病学调查，并对其致病性及致病因素进行了观察。发现人体蠕形螨感染率虽然高达６９．６０％，但有临床症状的并不多，人体蠕形螨不但与酒渣鼻、痤疮等皮肤病有关，而且与急性结膜炎、脸缘炎、，沙眼等眼外疾病有关，大多数受染者在一定的外部环境影响。