Effect of sodium hypochlorite on the biotransformation of toxicants in acute poisoning by psychotropic agents

In acute poisoning by amitriptyline, carbazepine, barbiturates, and ethanol, the effect of sodium hypochlorite on the metabolism of toxicants is manifested as a considerable reduction in their high blood concentrations through oxidative transformation to inactive water-soluble derivatives and as the enhanced urinary elimination of the latter. The rate of the above process depends on the used dose of sodium hypochlorite.     

Diagnostic possibilities of ultrasonic scanning of the knee joints in osteoarthrosis

AIM: To examine diagnostic potential of arthrosonography (ASG) in diagnosis of tendenitis in combination with synovitis in patients with gonarthrosis stage I-III by Kellgren's classification. MATERIAL AND METHODS: A total of 40 patients with gonarthrosis exacerbation were examined with x-ray and ultrasound scanning (80 joints). ASG was made on Aloka-SSD-630 device using two-dimentional scanning in 4 longitudinal and 4 transverse positions. RESULTS: Clinical symptoms of synovitis were predominant in patients with gonarthrosis x-ray stage II (68.3%). In ASG synovitis was detected in 41 (51.25%) of 48 knee joints with clinical picture of synovitis. Ultrasound detected such synovitis signs as increased amount of water in the knee joint cavity and b. suprapatellaris, thickening of the synovial membrane more than 0.3 cm and changes in its structure. Six (7.5%) joints were affected with subclinical synovitis diagnosed only in ASG. Ultrasound visualized Baker's cyst in 5 patients and in 5 knee joints. Periarthritis was detected in 77.5% joints, in 46.25% joints it combined with synovitis, ASG provided differential diagnosis of synovitis with periarthritis. Thinning of the cartilage was detected in most of the joints both in synovitis and in its absence but it was more significant in synovitis (62.5 and 40%, respectively). CONCLUSION: ASG is an informative diagnostic method in periarthritis and synovitis, including subclinical, and give additional information for x-ray diagnosis in gonarthrosis stage I-III.     

Biochemical indices of the healthy human being in a hermetic chamber with periodically ionized air

The content of 11-hydroxycorticosteroids, triglycerides and enzyme activity in blood as well as the content of 17-ketosteroids in urine of normal men kept for 16 days in an enclosure ventilated for 24--60 hours with bipolar ionized air (averaged unipolarity factor 1.58, concentration of positive ions 26--35 thous. cm-(3)) were measured. On DD 7--9 concentrations of 11-HOCS, triglycerides and 17-KS increased. This can be attributed to an activation of the hypophyseal-adrenal system in response to the enclosure effect. Further rapid return of the parameters to the normal may be associated with the cumulative effect of air ionization. This ionization at the doses used did not influence activities of creatine phosphokinase, aspartate aminotransferase and alphahydroxybutyrate dehydrogenase.