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51.
Objectives
The aim of this work is to describe indications, pros and cons and clinical use of the new Herbst appliances: Miniscope and Hanks Telescoping Herbst (HTH).Material and methods
The Miniscope combines a telescopic mechanism with traditional eyelet loops. To maximize the effectiveness of this appliance it is necessary to use a specific screw, the AppleCore, that improves lateral excursion. The HTH is a one-piece appliance, easy to install, with no more pieces to fumble with or falling in patient's mouth. HTH features a unique ball and socket design, allowing unrestricted mandibular excursions.Results and conclusions
The advantages of the Herbst appliance are unquestionable but there are some limitations too. The new Herbst Miniscope and HTH allow the clinician to overcome these limitations due to hinge modifications.The authors report the case of a 12 years old girl with class II malocclusion, deep bite and mandibular retrusion. At the beginning the patient was treated with fixed appliances and Class II elastics but, because of her poor compliance, a HTH was applied. 相似文献52.
Marcello Niceta Domenico Barbuti Neerja Gupta Carlos Ruggiero Eduardo F. Tizzano Luitgard Graul-Neumann Sabina Barresi Gen Nishimura Irene Valenzuela Fermina López-Grondona Paula Fernandez-Alvarez Chiara Leoni Christiane Zweier Andreas Tzschach Emilia Stellacci Andrea Del Fattore Bruno Dallapiccola Giuseppe Zampino Marco Tartaglia 《Clinical genetics》2020,97(2):362-369
53.
Yersinia enterocolitica is a rare cause of extra-intestinal disease. A case in a 60 year old butcher with hepatic cirrhosis who developed suppurative arthritis of the shoulder caused by Y enterocolitica is presented. There was no evidence of gastrointestinal infection or septicaemia. The severity of the illness was associated with various factors, including the underlying disease, the type of occupation, and the difficulties encountered in defining the optimal therapeutic regimen. 相似文献
54.
Topographic organization of neurons in the acoustic thalamus that project to the amygdala 总被引:11,自引:0,他引:11
Projections from the posterior thalamus to the amygdala have been implicated in the processing of the emotional significance of acoustic stimuli. The aim of the present studies was to determine which areas of the amygdala receive afferents from posterior thalamic structures that, in turn, receive afferents (presumably acoustic afferents) from the inferior colliculus. Projections from the posterior thalamus to the amygdala and striatum were examined in rats using anterograde and retrograde axonal transport techniques. Following injections of WGA-HRP into the posterior thalamic areas [including the medial division of the medial geniculate body, the posterior intralaminar nucleus (PIN) and the medial posterior complex (POM)], anterograde transport was seen in the lateral (AL), central (ACE), medial (AM), and basomedial (ABM) nuclei of the amygdala and in the amygdalostriatal transition area (AST) and posterior caudate putamen (CPU). Injection of WGA-HRP into each anterogradely labeled area produced retrograde transport to the posterior thalamus, but the pattern of transport varied with the site of the injection. Injections in AL and AST produced retrograde transport to neurons in the medial division of the medial geniculate body (MGM), PIN, suprageniculate nucleus (SG) and, to a lesser extent, the lateral posterior nucleus (LP). Injections of the ACE, AM, and ABM, in contrast, only labeled cells in POM. While the MGM, PIN, and SG each receive afferents from the inferior colliculus, POM does not. AL and AST, therefore, receive inputs from thalamic areas that, in turn, receive inputs from the inferior colliculus. 相似文献
55.
McGarrity TJ Ruggiero FM Chey WY Bajaj R Kelly JE Kauffman GL 《The American journal of gastroenterology》2000,95(7):1824-1828
This case details the development of a rapidly growing polypoid mass in the proximal stomach in a patient with known attenuated familial adenomatous polyposis. Surgical resection was required and histology showed hyperplasia with extensive areas of dysplastic adenomatous change. This case illustrates that patients with the attenuated form of familial adenomatous polyposis are at risk for multiple neoplasia distinct from those patients with the classic form of familial adenomatous polyposis. 相似文献
56.
Barbaro G Grisorio B Fruttaldo L Bacca D Babudieri S Torre D Francavilla R Rizzo G Belloni G Lucchini A Annese M Matarazzo F Hazra C Barbarini G 《BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy》2003,17(6):433-439
Background: The differential tolerability profile of various interferon (IFN)-α preparations used in combination with ribavirin for the treatment of chronic hepatitis C needs to be elucidated. Approximately 8% of patients receiving recombinant IFNα-2b plus ribavirin discontinue treatment because of adverse events. Human leucocyte IFNα is deemed to have a better safety profile than recombinant IFNα. We therefore compared the safety profile and efficacy of ribavirin combined with leucocyte IFNα or with recombinant IFNα-2b in treatment-naive patients with chronic hepatitis C. Study design: We randomised 423 patients to either leucocyte IFNα 3MU three times weekly plus ribavirin (210 patients) or the same dose of recombinant IFNα-2b plus ribavirin (213 patients). Patients were treated for 24 weeks and followed-up for a further 48 weeks. The primary endpoint was the safety profile of the two therapies; the secondary endpoint was the rate of sustained response. Results: In patients receiving leucocyte IFNα, the total number of adverse events was lower than in the group receiving recombinant IFNα (259 vs 441 patients), and the percentage of patients discontinuing treatment because of adverse events or laboratory abnormalities was significantly reduced (4% vs 11%; p = 0.013). Sustained response was observed in 47% of patients receiving leucocyte IFNα plus ribavirin and in 44% of patients receiving IFNα-2b plus ribavirin. Conclusions: Both therapeutic regimens were effective in inducing a sustained response in naive patients. However, the safety profile of leucocyte IFNα plus ribavirin was more favourable than that observed with the administration of recombinant IFNα-2b plus ribavirin, suggesting that leucocyte IFNα may be an alternative option in patients with reduced tolerability to other IFNs. 相似文献
57.
Brett Andrew Frenkiel Marc D. Pacifico Morris Ritz Graeme Southwick 《Aesthetic plastic surgery》2010,34(4):525-527
There are limited techniques described in the literature on how to lower the nipple–areola complex following surgery to the breast. We present a case of successful correction of a high-riding nipple using a Z-plasty technique with an 8-year follow-up in a breast reconstruction patient. The technique described may also be applicable to cases of high-riding nipples following aesthetic breast surgery such as reduction mammaplasty. 相似文献
58.
Roger T Anderson Lari Wenzel Ann P Walker Andrea Ruggiero Ronald T Acton Mark A Hall Diane C Tucker Elizabeth Thomson Barbara Harrison Edmund Howe Joan Holup Catherine Leiendecker-Foster Tara Power Paul Adams 《Genetics in medicine》2006,8(11):681-687
PURPOSE: Assess the quality of life impact of receiving indeterminate test results for hemochromatosis, a disorder involving HFE genetic mutations and/or elevated serum transferrin saturation and ferritin. METHODS: The study sample was from the Hemochromatosis and Iron Overload Screening Study, a large observational study of hemochromatosis among primary care patients in the US and Canada using HFE genotype and serum transferrin saturation and ferritin screening. Study subjects included 2,304 patients found with hemochromatosis risk of uncertain clinical significance. Assessed was SF-36 general health and emotional well-being before screening and six weeks after participants received their test results. Health worries were assessed after screening. RESULTS: Of the study subjects, 1,268 participants (51.5%) completed both assessments. Compared to normal controls, those with HFE mutations or elevated serum transferrin saturation and ferritin levels of uncertain significance were more likely to report diminished general health and mental well-being, and more health worries. These effects were associated with participants' belief of having tested positive for hemochromatosis or iron overload. CONCLUSION: Notification of indeterminate results from screening may be associated with mild negative effects on well-being, and might be a potential participant risk in screening programs for disorders with uncertain genotype-phenotype. 相似文献
59.
A. Reyes R. Pacifico B. Benitez E. Villanueva‐Uy H. Lam E. M. Ostrea Jr 《Child: care, health and development》2010,36(3):354-360
Background There is a need to assess neurobehavioral performance of children in developing countries using standardized developmental tools. Methods The Griffiths Mental Development Scales was evaluated in the Philippines by comparing the performance of 742 Filipino children longitudinally at 6, 12 and 24 months old to those of their British counterparts. Results The mean general and subquotient scores of Filipino children were all within average for age. Comparison with British children showed that except for performance subscales, Filipino children had significantly higher developmental subquotients at 6 months old. As the Filipino infants grew older, their developmental subquotients in all subscales were significantly lower, except for personal and social skills at 24 months old. The genetic predisposition as evidenced by modest maternal scores on the Wechsler Intelligence Scales and lack of familiarity with test materials are factors that may influence the developmental patterns of Filipino children. Conclusion Although the performance of the Filipino children in the Griffiths test were within average with age, their performance on developmental subquotients at later ages of 12 and 24 months were significantly lower than British children and may have been influenced by differences in ethnicity, cultural traditions and limited environmental resources. 相似文献
60.
Electron microscopy of extracts from diseased Polygonum convolvulus plants from Piedmont (Italy) revealed particles with the morphological features of a tospovirus. Sequencing of the full-length
small (S) and medium (M) genome segments indicated that the virus is a member of a new Tospovirus species provisionally named Polygonum ringspot virus. A feature distinguishing it from members of other Tospovirus species was the presence of a very short intergenic region on the S segment lacking the potential for formation of the predicted
hairpin structure involved in subgenomic expression. Antibodies made against purified nucleocapsids allowed serological comparison
with other tospovirus isolates and revealed a relationship with tomato yellow ring virus, and to a lesser extent, to iris
yellow spot virus. Serological tests detected the virus in various locations in northern and central Italy. The experimental
host range was wide, although in nature the virus appeared restricted to two Polygonum species.
Electronic supplementary material The online version of this article (doi:) contains supplementary material, which is available to authorized users. 相似文献