外伤后阴茎异常勃起介入治疗5例

目的探讨外伤后高流人性阴茎异常勃起的诊断与介入栓塞术治疗。方法对5例接受栓塞治疗的高流入性阴茎异常勃起患者进行回顾研究。结果4例患者经介入治疗后勃起完全消退，随访半年1例疲软度不如发病前且其阴茎勃起时不坚，性生活持续时间缩短，4例勃起程度和性生活持续时间与发病前相同。结论阴茎动脉血管造影检查在高流入性阴茎异常勃起的诊断有很高的价值；对其出血供血动脉进行超选择性栓塞是可靠的治疗方法。     

胫骨平台骨折合并内侧副韧带损伤的诊治体会

[目的]探讨胫骨平台骨折伴膝内侧副韧带损伤的诊断及治疗方法。[方法]回顾性分析本院1996年1月~2005年12月期间收治的52例胫骨平台骨折合并重度内侧副韧带损伤病例,并对有随访的49例(保守治疗21例,手术治疗28例)进行分析。[结果]随访10个月~9年(平均1.7年),按照Schatzker分型:Ⅱ型39例,Ⅲ型6例,Ⅵ型4例。骨折均切开复位内固定,对韧带损伤的治疗分为2组,保守治疗组21例,膝关节功能:优11例,良9例,差1例。手术治疗组28例,Ⅰ期修复19例:优17例,良2例。Ⅱ期修复9例:优5例,良3例,差1例。[结论]胫骨平台骨折合并内侧副韧带损伤Ⅰ期修复效果理想。     

搭建基础平台实现高职医学订单教学

搭建基础平台是改传统三年制医学教学“1＋1＋1”模式为“1＋1”模式，为以“市场为导向，就业为中心”的高职教学进行多向培养提供条件，既拓宽教学渠道，适应市场需求，解决学生就业问题，同时又有利于学校发展，符合教学新模式量展要求。     

血清痩素对老年男性骨质疏松的影响

目的 探讨血清瘦素水平对老年男性骨质疏松的影响。方法 选取年龄在60-92岁的158例老年男性，采用双能X线法（DXA）检测骨密度，并根据测值将受试者分为骨质疏松组与非骨质疏松组，用放射免疫法（RIA）检测两组空腹血清瘦素浓度，进行比较研究。结果 血清瘦素测值在不同年龄组间的差异无统计学意义，而在肥胖组与非肥胖组间有显著差异（P〈0．01）。在老年男性骨质疏松组血清瘦素测值明显低于非骨质疏松组，两者具有显著差异（P〈0．05）。结论 血清瘦索测值并不随老年男性的年龄而变化。但与老年男性的体重指数呈正相关，血清瘦素对老年男性骨质疏松有较好的预示及保护作用。     

鹿鞭的药理研究与临床应用展望

综述了近年来传统中药鹿鞭的药理作用以及临床应用，资料表明鹿鞭具有抗衰老、抗疲劳、增强机体免疫、促进伤口愈合等药理作用，且临床疗效突出，是具有开发前景的中药材。     

Serial CT findings of Paragonimus infested dogs and the Micro-CT findings of the worm cysts.

OBJECTIVE: To investigate the serial CT findings of Paragonimus westermani infected dogs and the microscopic structures of the worm cysts using Micro-CT. MATERIALS AND METHODS: This study was approved by the committee on animal research at our institution. Fifteen dogs infected with P. westermani underwent serial contrast-enhanced CT scans at pre-infection, after 10 days of infection, and monthly thereafter until six months for determining the radiologic-pathologic correlation. Three dogs (one dog each time) were sacrificed at 1, 3 and 6 months, respectively. After fixation of the lungs, both multi-detector CT and Micro-CT were performed for examining the worm cysts. RESULTS: The initial findings were pleural effusion and/or subpleural ground-glass opacities or linear opacities at day 10. At day 30, subpleural and peribronchial nodules appeared with hydropneumothorax and abdominal or chest wall air bubbles. Cavitary change and bronchial dilatation began to be seen on CT scan at day 30 and this was mostly seen together with mediastinal lymphadenopathy at day 60. Thereafter, subpleural ground-glass opacities and nodules with or without cavitary changes were persistently observed until day 180. After cavitary change of the nodules, the migratory features of the subpleural or peribronchial nodules were seen on all the serial CT scans. Micro-CT showed that the cyst wall contained dilated interconnected tubular structures, which had communications with the cavity and the adjacent distal bronchus. CONCLUSION: The CT findings of paragonimiasis depend on the migratory stage of the worms. The worm cyst can have numerous interconnected tubular channels within its own wall and these channels have connections with the cavity and the adjacent distal bronchus.     

The upregulation of glial glutamate transporter-1 participates in the induction of brain ischemic tolerance in rats.

Glial glutamate transporter-1 (GLT-1) plays an essential role in removing glutamate from the extracellular space and maintaining the glutamate below neurotoxic level in the brain. To explore whether GLT-1 plays a role in the acquisition of brain ischemic tolerance (BIT) induced by cerebral ischemic preconditioning (CIP), the present study was undertaken to observe in vivo changes in the expression of GLT-1 and glial fibrillary acidic protein (GFAP) in the CA1 hippocampus during the induction of BIT, and the effect of dihydrokainate (DHK), an inhibitor of GLT-1, on the acquisition of BIT in rats. Immunohistochemistry for GFAP showed that the processes of astrocytes were prolonged after a CIP 2 days before the lethal ischemic insult, which could protect pyramidal neurons in the CA1 hippocampus against delayed neuronal death induced normally by lethal ischemic insult. The prolonged processes extended into the area between the pyramidal neurons and tightly surrounded them. These changes made the pyramidal layer look like a 'shape grid'. Simultaneously, the prolonged and extended processes showed a great deal of GLT-1. Western blotting analysis showed significant upregulation of GLT-1 expression after the CIP, especially when it was administered 2 days before the subsequent lethal ischemic insult. Neuropathological evaluation by thionin staining showed that DHK dose-dependently blocked the protective role of CIP against delayed neuronal death induced normally by lethal brain ischemia. It might be concluded that the surrounding of pyramidal neurons by astrocytes and upregulation of GLT-1 induced by CIP played an important role in the acquisition of the BIT induced by CIP.     

腰椎间盘突出症早期手术并发症的回顾性分析

腰椎间盘突出是腰腿痛的主要原因,因患病率高,手术开展较为普及,关于其手术后并发症的相关报导也逐渐增多。为了进一步了解这些并发症的发生原因,我们将1993年2月至2004年12月手术治疗腰椎间盘突出症768例中所发生的74例早期并发症进行回顾性分析,针对手术的危险因素提出相应的     

伴有齿槽嵴裂的单侧唇裂术后继发鼻畸形的修复

目的探讨伴有齿槽嵴裂的单侧唇裂术后继发鼻畸形的修复方法。方法对34例伴有齿槽嵴裂的单侧唇裂术后继发畸形的患者,在行齿槽嵴植骨的同时,行彻底的鼻整形手术。结果术后随访1~3年,植骨区成活良好,鼻畸形较整形前明显改善,接近正常外形,效果满意。结论在行齿槽嵴植骨的同时,行彻底的鼻整形手术,能够取得满意的效果,并且节省了医疗费用,缩短了治疗时间。     

改良W形回肠代膀胱术的疗效观察(附36例报告)

目的 :探讨改良W形回肠代膀胱术的疗效。方法 :对 36例膀胱肿瘤患者行根治性膀胱切除、W形回肠代膀胱术 ,并对术式进行改进。结果 :36例手术时间平均 4 .2h。术后 31例随访 4～ 19个月 ,平均 10 .6个月 ,无严重并发症 ,均无瘤生存。患者一般于术后 3周自主可控性排尿 ,日间尿控率为 10 0 % ,术后 3、6、12个月夜间尿失禁发生率分别为 2 2 .5 %、11.1%及 6 .2 %。术后 6个月尿动力学检查膀胱容量 (36 0± 30 )ml,最大尿流率 (13.6± 2 .6 )ml/s,剩余尿量 (11.5± 5 .8)ml,充盈期膀胱压力明显低于尿道闭合压。新膀胱造影发现新膀胱呈球形 ,完全位于盆腔 ,未见输尿管反流。B超及IVU检查发现原上尿路积水 4例均明显减轻 ,其余未发现输尿管狭窄和上尿路积水征象。无高氯性酸中毒 ,肾功能正常。结论 :改良W形回肠代膀胱术手术时间短 ,操作简单 ,创伤轻 ,并发症少 ;新膀胱容量大 ,内压低 ,顺应性好 ,功能接近于正常膀胱 ,保持原位排尿 ,明显提高了患者术后生活质量 ,值得临床推广应用。