Adolescent girls with emotional disorders have a lower end‐tidal CO2 and increased respiratory rate compared with healthy controls

Hyperventilation has been linked to emotional distress in adults. This study investigates end‐tidal carbon dioxide (ETCO₂), respiratory rate (RR), and heart rate variability (HRV) in adolescent girls with emotional disorders and healthy controls. ETCO₂, RR, HRV, and ratings of emotional symptom severity were collected in adolescent female psychiatric patients with emotional disorders (n = 63) and healthy controls (n = 62). ETCO₂ and RR differed significantly between patients and controls. ETCO₂, HR, and HRV were significant independent predictors of group status, that is, clinical or healthy, while RR was not. ETCO₂ and RR were significantly related to emotional symptom severity and to HRV in the total group. ETCO₂ and RR were not affected by use of selective serotonin reuptake inhibitors. It is concluded that emotional dysregulation is related to hyperventilation in adolescent girls. Respiratory‐based treatments may be relevant to investigate in future research.     

Assessment tool for hospital admissions related to medications: development and validation in older patients

International Journal of Clinical Pharmacy - Background Medication-related hospital admissions (MRAs) are frequently used to measure outcomes in studies involving medication reviews. The process of...     

Brain simulation of action may be grounded in physical experience

An intriguing quality of our brain is that when actions are imagined, corresponding brain regions are recruited as when the actions are actually performed. It has been hypothesized that the similarity between real and simulated actions depends on the nature of motor representations. Here we tested this hypothesis by examining S.D., who never used her legs but is an elite wheel chair athlete. Controls recruited motor brain regions during imagery of stair walking and frontal regions during imagery of wheel chair slalom. S.D. showed the opposite pattern. Thus, brain simulation of actions may be grounded in specific physical experiences.