全文获取类型
收费全文 | 2598篇 |
免费 | 126篇 |
国内免费 | 140篇 |
专业分类
耳鼻咽喉 | 22篇 |
儿科学 | 46篇 |
妇产科学 | 31篇 |
基础医学 | 396篇 |
口腔科学 | 53篇 |
临床医学 | 304篇 |
内科学 | 462篇 |
皮肤病学 | 77篇 |
神经病学 | 110篇 |
特种医学 | 169篇 |
外科学 | 339篇 |
综合类 | 51篇 |
一般理论 | 1篇 |
预防医学 | 133篇 |
眼科学 | 25篇 |
药学 | 247篇 |
中国医学 | 16篇 |
肿瘤学 | 382篇 |
出版年
2023年 | 16篇 |
2022年 | 57篇 |
2021年 | 77篇 |
2020年 | 40篇 |
2019年 | 59篇 |
2018年 | 64篇 |
2017年 | 51篇 |
2016年 | 75篇 |
2015年 | 132篇 |
2014年 | 156篇 |
2013年 | 204篇 |
2012年 | 240篇 |
2011年 | 204篇 |
2010年 | 118篇 |
2009年 | 123篇 |
2008年 | 123篇 |
2007年 | 183篇 |
2006年 | 110篇 |
2005年 | 117篇 |
2004年 | 64篇 |
2003年 | 61篇 |
2002年 | 53篇 |
2001年 | 47篇 |
2000年 | 44篇 |
1999年 | 41篇 |
1998年 | 47篇 |
1997年 | 36篇 |
1996年 | 33篇 |
1995年 | 29篇 |
1994年 | 27篇 |
1993年 | 20篇 |
1992年 | 18篇 |
1991年 | 18篇 |
1990年 | 24篇 |
1989年 | 24篇 |
1988年 | 26篇 |
1987年 | 15篇 |
1986年 | 5篇 |
1985年 | 10篇 |
1984年 | 4篇 |
1983年 | 3篇 |
1982年 | 5篇 |
1981年 | 7篇 |
1980年 | 8篇 |
1978年 | 3篇 |
1977年 | 4篇 |
1976年 | 6篇 |
1975年 | 6篇 |
1958年 | 14篇 |
1955年 | 4篇 |
排序方式: 共有2864条查询结果,搜索用时 15 毫秒
71.
Eosinophils stimulate fibroblast DNA synthesis 总被引:9,自引:0,他引:9
Fibrosis complicates a number of chronic inflammatory diseases and occurs in some conditions following chronic hypereosinophilic syndromes. We assessed whether eosinophils might be a source of fibrogenic factors. Extracts of human and guinea pig cell populations enriched for eosinophils contained substances that stimulated tritiated thymidine incorporation by human fibroblasts. Supernatants derived from resting eosinophils and extracts prepared from eosinophil granules also contained fibrogenic factors. Our findings demonstrate a new potential role for eosinophils and suggest a causal relationship between tissue eosinophilia and scar formation in certain parasitic conditions. 相似文献
72.
Dae-Hyouk Bang Hyun-Jeong Noh Hyuk-Shin Cho 《Journal of Physical Therapy Science》2015,27(4):1191-1193
[Purpose] This study aimed to investigate the effects of body awareness training (BAT) on
mild visuospatial neglect in patients following acute stroke. [Subjects] The subjects were
12 stroke patients randomly assigned to either the experimental group (n1=6) or
control group (n2=6). [Methods] The experimental group underwent BAT for 15
minutes and then task-oriented training for 30 minutes a day, five times a week for three
weeks. The control group underwent task-oriented training for 30 minutes a day, five times
a week for three weeks. Assessments were made using the Motor-free Visual Perception Test
(MVPT), Line Bisection Test (LBT), and modified Barthel index (MBI). [Results] Following
the interventions, the experimental group showed a significant change in MVPT, LBT, and
MBI scores. [Conclusion] The results of this study suggest the feasibility and suitability
of BAT with task-oriented training for mild visuospatial neglect in patients with acute
stroke.Key words: Body awareness training, Neglect, Stroke 相似文献
73.
Jin-Won Noh Sang Ah Lee Hyo Jin Choi Jin Hyuk Hong Min Hee Kim Young Dae Kwon 《Journal of Physical Therapy Science》2015,27(4):1233-1237
[Purpose] The aim of this study was to examine the relationship between the intensity of
physical activity and symptoms of depression. [Subjects and Methods] We analyzed the
influence of different intensities of physical activity on depressive symptoms using the
data of 12,350 adults over the age of 20 years who had completed the 2011 Korea Health
Panel. After controlling for confounding variables, a multivariable logistic regression
analysis was conducted to identify the association between the intensity of physical
activity and depressive symptoms. [Results] The results showed that vigorous physical
activity had a significant effect on depressive symptoms. The incidence of depressive
symptoms was 1.487 (95% CI 1.137, 1.943) OR higher among people who did not participate in
regular activity than it was among those who took part in regular intense physical
activity. [Conclusion] It appears that physical activity affects depressive symptoms, a
result which is in agreement with previous studies. However, we also showed a difference
in influence according to activity intensity. Thus, the intensity of physical activity
should be considered when developing physical activity programs for improving depressive
symptoms.Key words: Intensity of physical activity, Depressive symptoms 相似文献
74.
Byoung-Sun Park Ju-Hyun Kim Mee-Young Kim Lim-Kyu Lee Seung-Min Yang Hye-Joo Jeon Won-Deok Lee Ji-Woong Noh Jeong-Uk Lee Taek-Yong Kwak Tae-Hyun Lee Ju-Young Kim Junghwan Kim 《Journal of Physical Therapy Science》2015,27(3):641-644
[Purpose] The purpose of this study was to investigate the effects of strengthening
exercises for the hip extensors on the gait performance and stability of patients with
hemiplegia. [Subjects and Methods] The subjects were fifteen stroke patients (ten males,
five females). The experimental subjects performed a hip extensor strengthening exercise
(HESE) program for a total of four weeks. [Results] The experimental subjects showed
significant improvements after the HESE program. Especially, walking speed and the
affected side stance phase time significantly increased after the HESE program.
Furthermore, the affected side stride length and symmetry index in the stance phase
significantly increased after HESE program. [Conclusion] These results suggest that the
HESE program may, in part, help to improve gait performance ability and stabilize physical
disability after stroke.Key words: Stroke patients, Hip extensor strengthening exercise (HESE) program, Gait function 相似文献
75.
Byoung-Sun Park Mee-Young Kim Lim-Kyu Lee Seung-Min Yang Won-Deok Lee Ji-Woong Noh Yong-Sub Shin Ju-Hyun Kim Jeong-Uk Lee Taek-Yong Kwak Tae-Hyun Lee Ju-Young Kim Junghwan Kim 《Journal of Physical Therapy Science》2015,27(5):1603-1607
[Purpose] The purpose of this study was to confirm the effects of both conventional
overground gait training (CGT) and a gait trainer with partial body weight support (GTBWS)
on spatiotemporal gait parameters of patients with hemiparesis following chronic stroke.
[Subjects and Methods] Thirty stroke patients were alternately assigned to one of two
treatment groups, and both groups underwent CGT and GTBWS. [Results] The functional
ambulation classification on the affected side improved significantly in the CGT and GTBWS
groups. Walking speed also improved significantly in both groups. [Conclusion] These
results suggest that the GTBWS in company with CGT may be, in part, an effective method of
gait training for restoring gait ability in patients after a stroke.Key words: Gait training, Spatiotemporal gait parameters, Stroke patients 相似文献
76.
Insang Hwang Donghoon Lim Young Beom Jeong Seung Chol Park Jun Hwa Noh Dong Deuk Kwon Taek Won Kang 《Asian journal of andrology》2015,17(5):811-814
Only 54% of prostate cancer cases in Korea are localized compared with 82% of cases in the US. Furthermore, half of Korean patients are upgraded after radical prostatectomy (41.6%–50.6%). We investigated the risk factors for upgrading and/or upstaging of low-risk prostate cancer after radical prostatectomy. We retrospectively reviewed the medical records of 1159 patients who underwent radical prostatectomy at five hospitals in Honam Province. Preoperative data on standard clinicopathological parameters were collected. The radical prostatectomy specimens were graded and staged and we defined a “worsening prognosis” as a Gleason score ≥ 7 or upstaging to ≥ pT3. Multivariate logistic regression models were used to assess factors associated with postoperative pathological upstaging. Among the 1159 patients, 324 were classified into the clinically low-risk group, and 154 (47.5%) patients were either upgraded or upstaged. The multivariable analysis revealed that the preoperative serum prostate-specific antigen level (odds ratio [OR], 1.131; 95% confidence interval [CI], 1.007–1.271; P= 0.037), percent positive biopsy core (OR: 1.018; 95% CI: 1.002–1.035; P= 0.032), and small prostate volume (≤30 ml) (OR: 2.280; 95% CI: 1.351–3.848; P= 0.002) were predictive of a worsening prognosis. Overall, 47.5% of patients with low-risk disease were upstaged postoperatively. The current risk stratification criteria may be too relaxed for our study cohort. 相似文献
77.
Jeremy YC Teoh Steffi KK Yuen James HL Tsu Charles KW Wong Brian SH Ho Ada TL Ng Wai-Kit Ma Kwan-Lun Ho Ming-Kwong Yiu 《Asian journal of andrology》2015,17(5):821-825
We investigated the prostate cancer detection rates upon transrectal ultrasound (TRUS)-guided biopsy in relation to digital rectal examination (DRE) and prostate-specific antigen (PSA), and risk factors of prostate cancer detection in the Chinese population. Data from all consecutive Chinese men who underwent first TRUS-guided prostate biopsy from year 2000 to 2013 was retrieved from our database. The prostate cancer detection rates with reference to DRE finding and PSA level of < 4, 4–10, 10.1–20, 20.1–50 and > 50 ng ml−1 were investigated. Multivariate logistic regression analyses were performed to investigate for potential risk factors of prostate cancer detection. A total of 2606 Chinese men were included. In patients with normal DRE, the cancer detection rates were 8.6%, 13.4%, 21.8%, 41.7% and 85.2% in patients with PSA < 4, 4–10, 10.1–20, 20.1–50 and > 50 ng ml−1 respectively. In patients with abnormal DRE, the cancer detection rates were 12.4%, 30.2%, 52.7%, 80.6% and 96.4% in patients with PSA < 4, 4–10, 10.1–20, 20.1–50 and > 50 ng ml−1 respectively. Older age, smaller prostate volume, larger number of biopsy cores, presence of abnormal DRE finding and higher PSA level were associated with increased risk of prostate cancer detection upon multivariate logistic regression analyses (P < 0.001). Chinese men appeared to have lower prostate cancer detection rates when compared to the Western population. Taking the different risk factors into account, an individualized approach to the decision of TRUS-guided biopsy can be adopted. 相似文献
78.
79.
The association between stress and health has been well researched in the past; however, comparatively few mediators have been tested to understand the underlying mechanism. With increasing awareness on mental well‐being, this study evaluated the relationship between perceived stress and perceived health and examined mental well‐being as a mediator. Two‐hundred undergraduates aged 21 to 26 years completed the English Perceived Stress Scale, Health Status Questionnaire and Asian Mental Well‐Being Scale that assess perceived stress, perceived health and mental well‐being, respectively. Factor analysis and structural equation modelling on the Perceived Stress Scale replicated the reported two‐factor structure after excluding an insignificant item. Linear multiple regression analyses indicated that perceived stress was negatively associated with perceived health. Results showed that mental well‐being partially mediated the relationship between perceived stress and perceived health, although it is acknowledged that this association could be bidirectional. Findings from the present study suggest that future research could focus on reducing stress and improving mental well‐being to alleviate the effect of stress on health. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
80.