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排序方式: 共有643条查询结果,搜索用时 15 毫秒
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Bahare Salehi Dmitry A. Konovalov Pascaline Fru Petrina Kapewangolo Gregorio Peron Mileski S. Ksenija Susana M. Cardoso Olivia R. Pereira Manisha Nigam Silvana Nicola Giuseppe Pignata Simona Rapposelli Simona Sestito Nanjangud V. Anil Kumar María de la Luz Cdiz‐Gurrea Antonio Segura‐Carretero Abhay P. Mishra Mehdi Sharifi‐Rad William C. Cho Yasaman Taheri William N. Setzer Javad Sharifi‐Rad 《Phytotherapy research : PTR》2020,34(9):2140-2158
The family Arecaceae includes 181 genera and 2,600 species with a high diversity in physical characteristics. Areca plants, commonly palms, which are able to grow in nearly every type of habitat, prefer tropical and subtropical climates. The most studied species Areca catechu L. contains phytochemicals as phenolics and alkaloids with biological properties. The phenolics are mainly distributed in roots followed by fresh unripe fruits, leaves, spikes, and veins, while the contents of alkaloids are in the order of roots, fresh unripe fruits, spikes, leaves, and veins. This species has been reputed to provide health effects on the cardiovascular, respiratory, nervous, metabolic, gastrointestinal, and reproductive systems. However, in many developing countries, quid from this species has been associated with side effects, which include the destruction of the teeth, impairment of oral hygiene, bronchial asthma, or oral cancer. Despite these side effects, which are also mentioned in this work, the present review collects the main results of biological properties of the phytochemicals in A. catechu. This study emphasizes the in vitro and in vivo antioxidant, antimicrobial, anticancer, and clinical effectiveness in humans. In this sense, A. catechu have demonstrated effectiveness in several reports through in vitro and in vivo experiments on disorders such as antimicrobial, antioxidant, or anticancer. Moreover, our findings demonstrate that this species presents clinical effectiveness on neurological disorders. Hence, A. catechu extracts could be used as a bioactive ingredient for functional food, nutraceuticals, or cosmeceuticals. However, further studies, especially extensive and comprehensive clinical trials, are recommended for the use of Areca in the treatment of diseases. 相似文献
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Bahare Salehi Monica Butnariu Mihaela Corneanu Ioan Sarac Sanja Vlaisavljevic Dusanka Kitic Amirhossein Rahavian Amirreza Abedi Morteza F. Karkan Indra D. Bhatt Arvind Jantwal Javad Sharifi‐Rad Clia F. Rodrigues Miquel Martorell Natlia Martins 《Phytotherapy research : PTR》2020,34(4):769-787
Chronic pelvic pain syndrome (CPPS) can be triggered by a various types of gynecological, gastrointestinal, urological, and musculoskeletal disorders. Recently, the role of the central nervous system has proven to be an integral part on the development of any chronic pain syndrome, including CPPS. However, owing to the complex and heterogeneous etiology and pathophysiology of CPPS, the establishment of effective therapeutic interventions remains challenging for both physicians and patients. Nonetheless, recent studies have pointed that medicinal plants and their secondary metabolites can be effectively used in CPPS therapy, besides contributing to restore the patients' quality of life and potentiate the conventional CPPS management. In this sense, this review aims to provide a careful overview on the biomedical data for the use of medicinal plants use and their secondary metabolites on CPPS management. 相似文献
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Javad Sharifi‐Rad Shahira M. Ezzat Mahitab H. El Bishbishy Dima Mnayer Farukh Sharopov Ceyda S. Kl Monica Neagu Carolina Constantin Mehdi Sharifi‐Rad Maria Atanassova Silvana Nicola Giuseppe Pignata Bahare Salehi Patrick V. T. Fokou Natlia Martins 《Phytotherapy research : PTR》2020,34(7):1474-1518
Rosmarinus species are aromatic plants that mainly grow in the Mediterranean region. They are widely used in folk medicine, food, and flavor industries and represent a valuable source of biologically active compounds (e.g., terpenoids, flavonoids, and phenolic acids). The extraction of rosemary essential oil is being done using three main methods: carbon dioxide supercritical extraction, steam distillation, and hydrodistillation. Furthermore, interesting antioxidant, antibacterial, antifungal, antileishmanial, anthelmintic, anticancer, anti‐inflammatory, antidepressant, and antiamnesic effects have also been broadly recognized for rosemary plant extracts. Thus the present review summarized data on economically important Rosmarinus officinalis species, including isolation, extraction techniques, chemical composition, pharmaceutical, and food applications. 相似文献
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Muhammad Imran Tanweer Aslam Gondal Muhammad Atif Muhammad Shahbaz Tahira Batool Qaisarani Muhammad Hanif Mughal Bahare Salehi Miquel Martorell Javad Sharifi‐Rad 《Phytotherapy research : PTR》2020,34(8):1812-1828
Apigenin is an edible plant‐derived flavonoid that has been reported as an anticancer agent in several experimental and biological studies. It exhibits cell growth arrest and apoptosis in different types of tumors such as breast, lung, liver, skin, blood, colon, prostate, pancreatic, cervical, oral, and stomach, by modulating several signaling pathways. Apigenin induces apoptosis by the activation of extrinsic caspase‐dependent pathway by upregulating the mRNA expressions of caspase‐3, caspase‐8, and TNF‐α. It induces intrinsic apoptosis pathway as evidenced by the induction of cytochrome c, Bax, and caspase‐3, while caspase‐8, TNF‐α, and B‐cell lymphoma 2 levels remained unchanged in human prostate cancer PC‐3 cells. Apigenin treatment leads to significant downregulation of matrix metallopeptidases‐2, ?9, Snail, and Slug, suppressing invasion. The expressions of NF‐κB p105/p50, PI3K, Akt, and the phosphorylation of p‐Akt decreases after treatment with apigenin. However, apigenin‐mediated treatment significantly reduces pluripotency marker Oct3/4 protein expression which might be associated with the downregulation of PI3K/Akt/NF‐κB signaling. 相似文献
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Correction for ‘Electrochemical investigation and amperometry determination iodate based on ionic liquid/polyoxotungstate/P-doped electrochemically reduced graphene oxide multi-component nanocomposite modified glassy carbon electrode’ by Minoo Sharifi et al., RSC Adv., 2021, 11, 8993–9007, DOI: 10.1039/D1RA00845E.The authors regret that eqn (3) and (4) were shown incorrectly in the original article.The corrected equations are shown below.3H4SiW4VW7VINi(H2O)O396− + IO3− → 3H2SiW2VW9VINi(H2O)O396− + I− + 3H2O (3)3H6SiW6VW5VINi(H2O)O396− + IO3− → 3H4SiW4VW7VINi(H2O)O396− + I− + 3H2O (4)The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers. 相似文献
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Evangelos Kalaitzakis Barbara Braden Palak Trivedi Yalda Sharifi Roger Chapman 《World journal of gastroenterology : WJG》2009,15(10):1273-1275
Intraductal papillary mucinous neoplasm (IPMN) is an increasingly reported entity. Extensive pancreatic calcification is generally thought to be a sign of chronic pancreatitis, but it may occur simultaneously with IPMN leading to diagnostic difficulties. We report a case of a patient initially diagnosed with chronic calcifying pancreatitis who was later shown to have a malignant IPMN. This case illustrates potential pitfalls in the diagnosis of IPMN in the case of extensive pancreatic calcification as well as clues that may lead the clinician to suspecting the diagnosis. The possible mechanisms of the relation between pancreatic calcification and IPMN are also reviewed. 相似文献
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Ghatee Mohammad Amin Mirhendi Hossein Karamian Mehdi Taylor Walter R. Sharifi Iraj Hosseinzadeh Massood Kanannejad Zahra 《Parasitology research》2018,117(11):3447-3458
Parasitology Research - Visceral leishmaniasis (VL) is endemic in Iran and is caused predominantly by Leishmania infantum, but L. tropica is emerging as an important cause. We studied the... 相似文献