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41.
T Taieb-Dogui M S Harzallah K Khlifa M Dogui S Ben Ammou P Jallon 《Clinical neurophysiology》2002,32(4):254-257
This 71 years old women without any history of epilepsy had diabetes mellitus. She was admitted for repetitive giratory seizures in relation with non-ketotic hyperglycaemia. The EEG showed right centro-parietal paroxysmal slow activity. Symptomatology disappeared within 48 hours after insulin therapy. One month later, she presented with a left hemiplegia in relation with a right sylvian infraction. The role of focal transitory ischaemia in connection with hyperglycaemia is discussed. 相似文献
42.
目的总结近20年来孤立性左肝胆管结石并发左肝胆管狭窄的临床治疗体会.方法原发性肝胆管结石1018例,年龄27~72岁,其中孤立性左肝胆管结石133例,手术治疗112例,对其临床资料进行回顾性分析,包括各肝管狭窄并发率,术前各项检查确诊率,手术治疗方式,再狭窄率.结果左肝管狭窄的发生率为598%,左外肝管和左内肝管分别为840%和848%,均以重度狭窄为主.狭窄切开整形后高位胆肠吻合术是处理左肝管狭窄的常用手术方式(522%),远期再狭窄率为171%;左半肝切除术施实率为194%,再狭窄率为00%;狭窄整形术和狭窄扩张术的施实率分别为90%和194%,再狭窄率分别为500%和923%.左外肝管狭窄通常采用肝段或肝叶切除术(787%),而左内肝管狭窄的处理则通常采用非左半肝切除术(848%).左内肝管狭窄的术前/后影像学确诊率明显低于左肝管和左外肝管,平均确诊率依次259%,933%和879%.结论二级肝管狭窄是孤立性左肝管结石的常见并发症,肝叶或肝段切除术是其首选治疗原则.过多依赖非肝叶/段切除术和不适当的肝段切除术是遗留狭窄和远期疗效差的重要原因 相似文献
43.
Intracellular recordings from neurons were carried out in cortical slices obtained from tissue removed from patients suffering from intractable seizures. The patients were divided into two groups based on the presence or absence of an anatomical abnormality that could be imaged preoperatively. The lesion or its surround was the presumptive epileptogenic area. The tissue removed from the patients without lesions was removed either for biopsy purposes or for access to epileptic tissue and was not considered epileptogenic. All neurons from patients without an imageable lesion, and some (19%) from patients with an imageable lesion, responded to orthodromic stimuli with a sequence of synaptic excitation followed by inhibition; these properties resembled those of normal rodent cortical slices. Different responses, classified as abnormal, were observed in 81% of the neurons in tissue specimens obtained near lesions. The most common was prolonged synaptic excitation with no noticeable inhibition, even at high stimulus strengths. In three resections, long latency all-or-none depolarization shifts were observed that resemble the classic paradoxical depolarization shift seen in in vivo extracellular recordings. Loss of specific inhibitory systems within the cortex may contribute in part to these abnormal responses. 相似文献
44.
美宝湿润烧伤膏在治疗慢性泪囊炎的应用 总被引:16,自引:8,他引:8
目的:观察美宝湿润烧伤膏(MEBO)在治疗慢性泪囊炎的应用价值。方法:对87例102只慢性泪囊炎采用泪道探通手术与MEBO置留治疗。常规泪点表面麻醉,扩张泪点,用生理盐水或氯霉素眼水冲洗鼻泪管、泪囊、泪小管,再用无菌注射器装入5ml MEBO,用5号自制泪道冲洗针沿泪道方向插入,直达泪囊推药,使鼻泪管、泪囊、泪小管内充满MEBO,一周后继续上述方法治疗,一般连续治疗2—5次。结果:治疗总有效率为100%,随访6个月,无一例复发。结论:在泪道探通手术后随即留置MEBO治疗慢性泪囊炎,临床效果良好,操作简单方便,经济有效,值得临床推广应用。 相似文献
45.
46.
【目的】研究拉米夫定对HBsAg阳性孕妇的乙肝病毒 (HBV)宫内阻断作用。【方法】拉米夫定组 43例 ,孕 2 8周起口服拉米夫定 ,每天 10 0mg至产后 30d。对照组 5 2例 ,未予用药。两组孕妇均于孕 2 8周、分娩前 ,其新生儿于生后 2 4h内免疫接种前抽静脉血检测HBsAg、HBeAg及HBV的定量。【结果】拉米夫定组孕妇HBV的DNA水平显著下降 (P <0 0 5 ) ,其新生儿宫内感染率 (16 3% )明显低于对照组 (32 7% ) ,P <0 0 5。两组孕妇及其新生儿未发现有不良反应。【结论】携带HBV孕妇产前服用拉米夫定可有效减少HBV宫内感染发生率。 相似文献
47.
S Ben Becher J el Mabrouk A Debbiche A Hammou N Ghram S Makni T Boudhina 《Archives fran?aises de pédiatrie》1992,49(9):799-802
BACKGROUND. Schwartz-Jampel syndrome is a rare disorder inherited as an autosomal recessive trait and characterized by growth retardation, multiple skeletal abnormalities, myotonia-like muscle disorders and unusual facies. CASE REPORTS. Case n. 1: A boy, aged 3 years 4 months, was admitted for acute respiratory disease. His main abnormalities included rigid facial expression, blepharophimosis, puckered lips, short neck, pectus carinatum, acetabular dysplasia with coxa vara, platyspondyly and marked growth retardation. There was a continuous muscle fiber activity at rest, with abnormal discharges originating in the muscle component of the neuromuscular junction. Blood investigations revealed low values of IgA. The child died at 4 years. Case n. 2: The sister of case n. 1 was examined at 14 months of age. She presented milder facies abnormalities, difficulties of gait because of stiff hips, muscular hypertrophy, coxa vara and growth retardation. X-rays showed skeletal abnormalities and the electromyogram was similar to those of her brother. She had dislocation of her optic lens. CONCLUSION. These 2 sibs have the characteristic manifestations of Schwartz-Jampel syndrome. Parental consanguinity was also present. The IgA deficiency observed in case n. 1 and the lens dislocation in case n. 2 have both been occasionally reported in this syndrome. 相似文献
48.
N Ben Zineb S Zine M Bellasfar M J Mesaad R Sfar 《Revue fran?aise de gynécologie et d'obstétrique》1992,87(12):591-593
The authors report a case of a pregnant woman with Takayasu's arteritis and Crohn's disease. The course of pregnancy was uneventful. It is suggested that these two inflammatory diseases may be immunologically related. A brief review of the literature confirm that fetal and maternal prognosis are generally excellent. 相似文献
49.
J L Pérez Arellano N M Barrios González T Martín Domínguez M L Sánchez Benítez de Soto A Jiménez López 《Journal of investigational allergology & clinical immunology》1992,2(4):219-228
Experimental models of hypersensitivity pneumonitis are important tools for the study of the pathogenesis of this disease. In this paper we review the characteristics of the main animal models developed until now. The HP models in rats seem to be particularly appropriate for studying pigeon fancier's disease and the HP induced by chemicals, as well as for studying mediators of acute lesions induced by immunocomplexes. However, the HP models developed in rats are of less value in the evaluation of other aspects of the pathogenesis of this clinical entity in humans. The murine models of HP offer several advantages: the ease and simplicity of intranasal administration, the ability to produce acute and subacute pulmonary lesions similar to those found in humans, the possibility of reproducing lesions similar to those of nonaffected exposed subjects and the possibility of pharmacologically modulating the process. Their disadvantages lie in the different pulmonary lymphocyte response and the difficulty in reproducing a model of chronic fibrosis. The HP models in rabbits are extraordinarily useful for evaluating the immunological mechanisms through which subjects repeatedly exposed to the antigen do not develop clinical manifestations. However, the rabbit has several immunological differences when compared to humans, and the effect of some immunomodulators in this animal is different. The models of HP in guinea-pigs have as advantages the ease in handling the animals, the possibility of pharmacological manipulation, and the ability to induce an acute phase that is very similar to that observed in humans. The drawback, however, is the low lymphocyte response and the striking eosinophilic reaction that contrast with the bronchoalveolar data found in HP in humans. In conclusion, there is no ideal model to reproduce all the findings observed in humans, suggesting that the experimental animal and the method of developing HP should be selected on the basis of concrete research aims. 相似文献
50.