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71.
Tiberio GA Piardi T Cerea K Ronconi M Bertoloni G Frassi E Portolani N Giulini SM 《Chirurgia italiana》2005,57(3):273-281
Our aim was to evaluate the short-term results of a series of 65 consecutive laparoscopic adrenalectomies performed on 63 patients with benign or metastatic tumours measuring < or = 7 cm. The surgical indication was primary hyperaldosteronism in 32 cases, pheochromocytoma in 7, Cushing syndrome and disease in 5 and 2 cases, respectively, incidentaloma in 11 and metastasis in 8 cases. The mean tumour size was 3.9 cm (range 0.6-7). Operative time averaged 130 min (range 45-270). In one case we produced an iatrogenic lesion by sectioning a peripheral recurrent branch of the left renal artery with consequent partial renal infarction. The conversion rate to the open approach was 6.1%; the morbidity rate was 4.6%. The mean hospital stay was 4 days (range 3-11). All patients were re-examined 30 days after surgery and no additional complications were observed. At this time 93.2% of patients with primary secreting tumours showed normal hormonal assays. Considering the 38 patients chronically treated during the preoperative period, we noted that the intake of specific drugs was suspended in 34.2%, reduced in 36.8%, maintained in 26.4% and transitorily augmented in 2.6%. On these basis we confirm the efficacy and safety of this surgical treatment. 相似文献
72.
Salari K Choudhry S Tang H Naqvi M Lind D Avila PC Coyle NE Ung N Nazario S Casal J Torres-Palacios A Clark S Phong A Gomez I Matallana H Pérez-Stable EJ Shriver MD Kwok PY Sheppard D Rodriguez-Cintron W Risch NJ Burchard EG Ziv E 《Genetic epidemiology》2005,29(1):76-86
Genetic association studies in admixed populations may be biased if individual ancestry varies within the population and the phenotype of interest is associated with ancestry. However, recently admixed populations also offer potential benefits in association studies since markers informative for ancestry may be in linkage disequilibrium across large distances. In particular, the enhanced LD in admixed populations may be used to identify alleles that underlie a genetically determined difference in a phenotype between two ancestral populations. Asthma is known to have different prevalence and severity among ancestrally distinct populations. We investigated several asthma-related phenotypes in two ancestrally admixed populations: Mexican Americans and Puerto Ricans. We used ancestry informative markers to estimate the individual ancestry of 181 Mexican American asthmatics and 181 Puerto Rican asthmatics and tested whether individual ancestry is associated with any of these phenotypes independently of known environmental factors. We found an association between higher European ancestry and more severe asthma as measured by both forced expiratory volume at 1 second (r=-0.21, p=0.005) and by a clinical assessment of severity among Mexican Americans (OR: 1.55; 95% CI 1.25 to 1.93). We found no significant associations between ancestry and severity or drug responsiveness among Puerto Ricans. These results suggest that asthma severity may be influenced by genetic factors differentiating Europeans and Native Americans in Mexican Americans, although differing results for Puerto Ricans require further investigation. 相似文献
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The tautog, Tautoga onitis, and cunner, Tautogolabrus adspersus, are marine fishes which are closely related taxonomically (family Labridae), have similar habits, the same ecological requirements and are found in the same areas. However, they differ markedly in their longevity. The tautog is longer-lived, reaching an estimated average age of 34 years. It attains sexual maturity at 3--4 years of age. The cunner, on the other hand, lives to about 5--6 years of age and is sexually mature at about one year. An examination of their respective capacities for photoreactivation using cells in tissue culture derived from these fishes revealed marked differences in the rate of monomerization of ultraviolet-induced pyrimidine dimers from their DNA. Radiochromatographic analysis of dimers in the tautog showed that half the dimers were removed within a period of 10 min of exposure to photoreactivating light whereas a 50-min exposure was required to photoreactivate dimers to this same level in the cunner. Dark repair of dimers was measured by radiochromatography and by endonuclease assay. The two methods showed similar low levels of excision repair in both species. 相似文献
75.
Sánchez Ayéndez M Suárez-Pérez E Vázquez MO Vélez-Almodóvar H Nazario CM 《Puerto Rico health sciences journal》2001,20(4):351-359
This is the first national study of breast-cancer knowledge, beliefs, and early detection practices among elderly women (65+) in Puerto Rico. Cancer breast examination (CBE) was the most common early detection practice, followed by the mammogram, with breast self exam (BSE) a distant third. The primary reasons most often cited for never having a mammogram related to both personal and external factors: not having symptoms, negligence or forgetfulness, and not having a physician's referral. No statistically significant difference (p < 0.05) was found between knowledge and early detection practices. Conversely, beliefs had an impact on preventive behavior. Those who had less misconceptions were most likely to have had a CBE or a mammogram. Bivariate analysis demonstrated that age was associated with performing a BSE once or twice monthly, ever having a mammogram, and having a mammogram in the past two years. A higher socioeconomic status was associated to performing BSE and ever having had a mammogram. Education correlated positively to ever having a mammogram or having a mammogram in the two years prior to the interview. Factors that explained compliance with a mammogram in the last two years included referral from a physician, owning a car, and receiving information after menopause on breast cancer from a health care provider. A gynecological visit increased the probability of having had a mammogram during the last two years. Logistic regression determined that a referral from a physician was the most important factor for mammogram compliance when a combination of variables were considered. 相似文献
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Nuzzo G Giuliante F Ardito F Giovannini I Aldrighetti L Belli G Bresadola F Calise F Dalla Valle R D'Amico DF Gennari L Giulini SM Guglielmi A Jovine E Pellicci R Pernthaler H Pinna AD Puleo S Torzilli G Capussotti L;Italian Chapter of the International Hepato-Pancreato-Biliary Association Cillo U Ercolani G Ferrucci M Mastrangelo L Portolani N Pulitanò C Ribero D Ruzzenente A Scuderi V Federico B 《Archives of surgery (Chicago, Ill. : 1960)》2012,147(1):26-34
80.
Nazario Portolani Gianluca Baiocchi Federico Gheza Sarah Molfino Luigi Grazioli Lucio Olivetti Laura Romanini Eleonora Frassi Stefano Maria Giulini 《World journal of surgery》2014,38(10):2685-2691