全文获取类型
收费全文 | 13905篇 |
免费 | 972篇 |
国内免费 | 435篇 |
专业分类
耳鼻咽喉 | 187篇 |
儿科学 | 443篇 |
妇产科学 | 198篇 |
基础医学 | 1624篇 |
口腔科学 | 298篇 |
临床医学 | 1383篇 |
内科学 | 2979篇 |
皮肤病学 | 274篇 |
神经病学 | 905篇 |
特种医学 | 456篇 |
外国民族医学 | 2篇 |
外科学 | 1439篇 |
综合类 | 1127篇 |
现状与发展 | 1篇 |
一般理论 | 2篇 |
预防医学 | 1071篇 |
眼科学 | 482篇 |
药学 | 1085篇 |
6篇 | |
中国医学 | 368篇 |
肿瘤学 | 982篇 |
出版年
2024年 | 25篇 |
2023年 | 129篇 |
2022年 | 261篇 |
2021年 | 465篇 |
2020年 | 310篇 |
2019年 | 376篇 |
2018年 | 543篇 |
2017年 | 388篇 |
2016年 | 373篇 |
2015年 | 503篇 |
2014年 | 589篇 |
2013年 | 684篇 |
2012年 | 1003篇 |
2011年 | 1071篇 |
2010年 | 639篇 |
2009年 | 438篇 |
2008年 | 739篇 |
2007年 | 765篇 |
2006年 | 656篇 |
2005年 | 710篇 |
2004年 | 620篇 |
2003年 | 601篇 |
2002年 | 569篇 |
2001年 | 462篇 |
2000年 | 494篇 |
1999年 | 391篇 |
1998年 | 119篇 |
1997年 | 98篇 |
1996年 | 102篇 |
1995年 | 90篇 |
1994年 | 54篇 |
1993年 | 51篇 |
1992年 | 143篇 |
1991年 | 118篇 |
1990年 | 103篇 |
1989年 | 108篇 |
1988年 | 88篇 |
1987年 | 75篇 |
1986年 | 66篇 |
1985年 | 53篇 |
1984年 | 38篇 |
1983年 | 23篇 |
1982年 | 13篇 |
1981年 | 9篇 |
1980年 | 11篇 |
1979年 | 14篇 |
1977年 | 12篇 |
1973年 | 9篇 |
1970年 | 9篇 |
1965年 | 8篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
22.
白内障超声乳化吸出及囊袋内人工晶体植入术 总被引:1,自引:0,他引:1
为观察和评价超声乳化白内障吸出术的临床效果、特点、并发病及防治措施,对41 眼白内障施行超声乳化吸出术及小切口(6mm)囊袋内人工晶体植入术,并以同期的白内障患者41眼行现代囊外摘除及后房型人工晶体植入做对照。结果:术后6个月,视力≥1.0者占43.9%>0.8者占70.7≥0.5者占92.7%,均明显高于对照组(P<0.001),术后平均散光为1.04±0.81,1,低于对照组(P<0.01)。白内障超声乳化吸出并囊袋内人工晶体植入术的复明效果优于囊外摘除并后房型人工晶体植入术。 相似文献
23.
成人高原心脏病临床分型的探讨 总被引:1,自引:1,他引:0
本文总结了680例成人高原心脏病临床资料,依照其临床表现、X线、心电图等项检查,提出了临床上较为实用的诊断和分型意见。 相似文献
24.
25.
S Ponce G Orive R M Hernández A R Gascón J M Canals M T Mu?oz J L Pedraz 《Journal of controlled release》2006,116(1):28-34
Alginates are the most employed biomaterials for cell encapsulation due to their abundance, easy gelling properties and apparent biocompatibility. However, as natural polymers different impurities including endotoxins, proteins and polyphenols can be found in their composition. Several purification protocols as well as different batteries of assays to prove the biocompatibility of the alginates in vitro have been recently developed. However, little is known about how the use of alginates with different purity grade may affect the host immune response after their implantation in vivo. The present paper investigates the long-term functionality and biocompatibility of murine erythropoietin (EPO) secreting C2C12 cells entrapped in microcapsules elaborated with alginates with different properties (purity, composition and viscosity). Results showed that independently of the alginate type employed, the animals presented elevated hematocrit levels until day 130, remaining at values between 70-87%. However, histological analysis of the explanted devices showed higher overgrowth around non-biomedical grade alginate microcapsules which could be directly related with higher impurity content of this type of alginate. Although EPO delivery may be limited by the formation of a fibrotic layer around non-biomedical grade alginate microcapsules, the high EPO secretion of the encapsulated cells together with the pharmacodynamic behaviour and the angiogenic and immune-modulatory properties of EPO result in no direct correlation between the biocompatibility of the alginate and the therapeutic response obtained. 相似文献
26.
OBJECTIVE: To investigate the factors responsible for Pseudomonas aeruginosa nosocomial cross-infection in the intensive care unit (ICU) and provide effective measure for the prevention and management. METHODS: The homology of 7 Pseudomonas aeruginosa strains isolated from the patients in the ICU and the environment was examined by biological, serological, drug-resistance and plasmid analysis. RESULTS: The results of serological and plasmid analyses had good consistency, which demonstrated that the 7 Pseudomonas aeruginosa strains originated from solution in the oxygen humidifier, with uniform serological and plasmid type, and belonged to the same clone with cross-infection by contact between the patients or nursing staff and the objects in the ICU. CONCLUSION: Serological and plasmid analyses are more practical for identifying the sources of Pseudomonas aeruginosa cross-infection, which can be prevented by strict disinfection of the instrument and supervision of the nursing staff in the ICU. 相似文献
27.
耳源性脑疝25例,抢救成功者19例。采用单纯脑脓肿穿刺抽脓抢救脑疝6例,仅1例成功;开颅减压术抢救脑疝20例,18例抢救成功。本组临床实践和文献报道都说明耳源性脑疝一旦发生应即刻行开颅减压术,能卓有成效地抢救生命 相似文献
28.
吡酮酸类抗菌药物的研究Ⅷ.1-对氟苯基-6-氟-1,4-二氢-4-氧-7-(1-哌嗪)噌啉-3-羧酸及其类似物的合成和构效关系 总被引:1,自引:0,他引:1
为探讨构效关系,合成了1-对氟苯基-6-氟-1,4-二氢-4-氧-7-(1-哌嗪)噌啉-3-羧酸及其喹啉、萘啶、吡啶[2,3-C]哒嗪环系类似物16个。测定了对大肠杆菌的MIC。用Hückel分子轨道理论(HMO)方法计算了四个母体环上电子密度。结果表明:环中氮的位置对药效团——3位羧基和4位羰基氧原子上电子密度的影响较大而影响其抗菌活性。喹啉、萘啶两环系的3位羧基和4位羰基氧原子上的电子密度较高,其体外抗菌活性较高;而噌啉及吡啶[2,3-C]哒嗪两环系的电子密度较低,其体外抗菌活性较低甚至消失。 相似文献
29.
M A Brancós P Peris J M Miró A Monegal J M Gatell J Mallolas J Mensa S García J Mu?oz-Gomez 《Seminars in arthritis and rheumatism》1991,21(2):81-87
Over a 6-year period (1982 to 1988), 36 episodes of septic arthritis were diagnosed in 35 heroin addicts from Barcelona, Spain. Thirty (86%) were men and five (14%) were women, with a mean age of 24 years (range, 14 to 39). Twenty-nine episodes (80%) were monoarticular and seven (20%) were oligoarticular. The sacroiliac (16 cases), sternoclavicular (8), hip (5), and shoulder (4) joints were most frequently infected. Staphylococcus aureus and Pseudomonas aeruginosa were the etiological agents in 75% and 11% of episodes, respectively. Response to antibiotic treatment was good in 32 cases (90%), eight patients needed surgical drainage, and none died. We conclude that septic arthritis in heroin addicts localizes predominantly in axial joints. In our geographic area, infection with S aureus is more frequent than with gram-negative rods such as P aeruginosa or Serratia marcescens, which are most frequently found in reports from the United States. 相似文献
30.
J I Bilbao J M Longo A Martín-Palanca L Mu?oz-Galindo 《Journal of vascular and interventional radiology : JVIR》1992,3(3):553-555
Two cases are presented in which conventional approaches did not permit dilation of and stent placement in obstructed ureters. In patients with iatrogenic ureteral laceration or rigid ureteral kinking, direct percutaneous translumbar puncture may provide a safe alternative. The authors' technique is described. 相似文献