全文获取类型
收费全文 | 2381篇 |
免费 | 226篇 |
国内免费 | 57篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 150篇 |
妇产科学 | 71篇 |
基础医学 | 236篇 |
口腔科学 | 76篇 |
临床医学 | 199篇 |
内科学 | 708篇 |
皮肤病学 | 51篇 |
神经病学 | 119篇 |
特种医学 | 229篇 |
外科学 | 236篇 |
综合类 | 98篇 |
预防医学 | 131篇 |
眼科学 | 33篇 |
药学 | 140篇 |
中国医学 | 5篇 |
肿瘤学 | 171篇 |
出版年
2023年 | 20篇 |
2022年 | 30篇 |
2021年 | 68篇 |
2020年 | 42篇 |
2019年 | 38篇 |
2018年 | 53篇 |
2017年 | 76篇 |
2016年 | 70篇 |
2015年 | 59篇 |
2014年 | 107篇 |
2013年 | 118篇 |
2012年 | 99篇 |
2011年 | 109篇 |
2010年 | 116篇 |
2009年 | 122篇 |
2008年 | 98篇 |
2007年 | 139篇 |
2006年 | 89篇 |
2005年 | 82篇 |
2004年 | 75篇 |
2003年 | 46篇 |
2002年 | 42篇 |
2001年 | 55篇 |
2000年 | 53篇 |
1999年 | 41篇 |
1998年 | 89篇 |
1997年 | 71篇 |
1996年 | 65篇 |
1995年 | 59篇 |
1994年 | 57篇 |
1993年 | 48篇 |
1992年 | 30篇 |
1991年 | 26篇 |
1990年 | 31篇 |
1989年 | 43篇 |
1988年 | 41篇 |
1987年 | 36篇 |
1986年 | 34篇 |
1985年 | 29篇 |
1984年 | 20篇 |
1983年 | 17篇 |
1982年 | 11篇 |
1981年 | 7篇 |
1980年 | 10篇 |
1979年 | 11篇 |
1978年 | 11篇 |
1976年 | 12篇 |
1975年 | 14篇 |
1969年 | 7篇 |
1968年 | 7篇 |
排序方式: 共有2664条查询结果,搜索用时 125 毫秒
91.
Practice patterns and clinical outcomes among non‐ST‐segment elevation acute coronary syndrome (NSTE‐ACS) patients presenting to primary and tertiary hospitals: Insights from the EARLY glycoprotein IIb/IIIa inhibition in NSTE‐ACS (EARLY‐ACS) trial
下载免费PDF全文
![点击此处可从《Catheterization and cardiovascular interventions》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Olga Toleva MD Cynthia M. Westerhout PhD Manohara P.J. Senaratne MBBS PhD Christoph Bode MD Magnus Lindroos MD PhD Vitaly A. Sulimov MD PhD Gilles Montalescot MD L. Kristin Newby MD MHS Robert P. Giugliano MD SM Frans Van de Werf MD PhD Paul W. Armstrong MD 《Catheterization and cardiovascular interventions》2014,84(6):934-942
92.
Procedural variation in the performance of primary percutaneous coronary intervention for ST‐elevation myocardial infarction: A SCAI‐based survey study of US interventional cardiologists
下载免费PDF全文
![点击此处可从《Catheterization and cardiovascular interventions》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Austin Chiang MD Hemal Gada MD MBA Susheel K. Kodali MD Michael S. Lee MD Allen Jeremias MD Duane S. Pinto MD MPH Sripal Bangalore MD MHA Robert W. Yeh MD MSc Timothy D. Henry MD Georgina Lopez‐Cruz BS MSHA Roxana Mehran MD Ajay J. Kirtane MD SM 《Catheterization and cardiovascular interventions》2014,83(5):721-726
93.
Lin Zhang Joseph JY Sung Jun Yu Siew C Ng Sunny H Wong Chi H Cho Simon SM Ng Francis KL Chan William KK Wu 《The Journal of pathology》2014,233(2):103-112
Helicobacter pylori and Epstein–Barr virus (EBV) account for roughly 80% and 10%, respectively, of gastric carcinomas worldwide. Autophagy is an evolutionarily conserved and intricately regulated cellular process that involves the sequestration of cytoplasmic proteins and organelles into double‐membrane autophagosomes that eventually fuse with lysosomes for degradation of the engulfed content. Emerging evidence indicates that xenophagy, a form of selective autophagy, plays a crucial role in the pathogenesis of H. pylori‐ and EBV‐induced gastric cancer. Xenophagy specifically recognizes intracellular H. pylori and EBV and physically targets these pathogens to the autophagosomal–lysosomal pathway for degradation. In this connection, H. pylori or EBV‐induced dysregulation of autophagy may be causally linked to gastric tumourigenesis and therefore can be exploited as therapeutic targets. This review will discuss how H. pylori and EBV infection activate autophagy and how these pathogens evade recognition and degradation by the autophagic pathway. Elucidating the molecular aspects of H. pylori‐ and EBV‐induced autophagy will help us better understand the pathogenesis of gastric cancer and promote the development of autophagy modulators as antimicrobial agents. Published by John Wiley & Sons, Ltd 相似文献
94.
95.
Arthur R. Menezes Carl J. Lavie Richard V. Milani Daniel E. Forman Marjorie King Mark A. Williams 《Progress in cardiovascular diseases》2014
Coronary heart disease (CHD) is a significant cause of morbidity and mortality in the United States (US). In addition to this, many of the risk factors of CHD, such as obesity, sedentary lifestyle, diabetes mellitus, and poor nutrition, are disproportionately high in the US. Despite the many known benefits of cardiac rehabilitation (CR), referral and participation rates in these programs are paradoxically low. Over the course of this review, we will discuss some of the many benefits of CR, some of the risk factors for CHD in the US, and factors that affect referral and participation in these programs. 相似文献
96.
97.
98.
99.
Palladini G Russo P Foli A Milani P Lavatelli F Obici L Nuvolone M Brugnatelli S Invernizzi R Merlini G 《Annals of hematology》2012,91(1):89-92
The increasing number of effective agents allows rescue therapy of patients with light-chain (AL) amyloidosis refractory to
≥2 previous treatments. Lenalidomide is effective in this disease and its toxicity profile encourages its use in salvage regimens.
All the patients with AL amyloidosis refractory to both melphalan and bortezomib referred to our center between July 2007
and July 2009 were treated with the combination of lenalidomide and dexamethasone. Twenty-four consecutive patients were enrolled.
Seventy-nine percent were also refractory to thalidomide. Two patients died before evaluation of response, and 50% experienced
severe adverse events. Survival was significantly shorter in subjects with troponin I >0.1 ng/mL and in patients diagnosed
<18 months before treatment initiation. Hematologic response was observed in 41% of patients and prolonged survival (median
10 months vs. not reached, P = 0.005) independently from troponin I concentration and from pre-treatment disease duration. Salvage therapy beyond second
line of treatment can improve survival in AL amyloidosis and lenalidomide plus dexamethasone is a valuable option in this
setting. 相似文献
100.
Tuncer HH Rana N Milani C Darko A Al-Homsi SA 《World journal of gastroenterology : WJG》2012,18(16):1851-1860
Recognition and management of gastrointestinal and hepatic complications of hematopoietic stem cell transplantation has gained increasing importance as indications and techniques of transplantation have expanded in the last few years. The transplant recipient is at risk for several complications including conditioning chemotherapy related toxicities, infections, bleeding, sinusoidal obstruction syndrome, acute and chronic graft-versus-host disease (GVHD) as well as other long-term problems. The severity and the incidence of many complications have improved in the past several years as the intensity of conditioning regimens has diminished and better supportive care and GVHD prevention strategies have been implemented. Transplant clinicians, however, continue to be challenged with problems arising from human leukocyte antigen-mismatched and unrelated donor transplants, expanding transplant indications and age-limit. This review describes the most commonly seen transplant related complications, focusing on their pathogenesis, differential diagnosis and management. 相似文献