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Jeff Cain Tom Campbell Heather Brennan Congdon Kim Hancock Megan Kaun Paul R. Lockman R. Lee Evans 《American journal of pharmaceutical education》2014,78(7)
It is time for colleges and schools of pharmacy to examine and confront the rising costs of pharmacy education and the increasing student loan debt borne by graduates. These phenomena likely result from a variety of complex factors. The academy should begin addressing these issues before pharmacy education becomes cost-prohibitive for future generations. This paper discusses some of the more salient drivers of cost and student debt load and offers suggestions that may help alleviate some of the financial pressures. 相似文献
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Outcome of patients with systemic light chain amyloidosis with concurrent renal and cardiac involvement 下载免费PDF全文
Talha Badar Amanda Megan Cornelison Nina D. Shah Qaiser Bashir Simrit Parmar Krina Patel Chitra Hosing Uday Popat Donna M. Weber Sheeba K. Thomas Jatin J. Shah Robert Z. Orlowski Richard E. Champlin Muzaffar H. Qazilbash 《European journal of haematology》2016,97(4):342-347
Cardiac involvement in systemic light chain amyloidosis (AL) is generally associated with a worse outcome, especially if other organs are also involved. We sought to determine whether concurrent cardiac and renal involvement were associated with a worse outcome than either organ alone. We identified 129 patients with AL, who received high‐dose chemotherapy followed by autologous hematopoietic stem cell transplantation (auto‐HCT) at our institution between 1997 and 2014. Ninety‐nine patients had either renal (group 1: n = 62, 62%), cardiac (group 2: n = 20, 20%), or both cardiac and renal (group 3: n = 17, 17%) involvement. The overall hematological response rate (CR+VGPR+PR) post‐auto‐HCT in groups 1, 2, and 3 was 69%, 74% and 82%, respectively (P = 0.62). Overall, organ response in groups 1, 2, and 3 was 39%, 42%, and 70%, respectively. The median PFS from auto‐HCT in groups 1, 2, and 3 was not reached (NR), 13.3 and 21 months, respectively (P = 0.02). The median OS in groups 1, 2, and 3 was 120, 46, and 60 months, respectively (P = 0.1). In conclusion, median PFS and OS in patients with concurrent cardiac and renal AL were comparable to patients with cardiac AL only, but worse than patients with renal AL. 相似文献
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Hailey Steuber DeAndre Williams Megan A. Rech 《The American journal of emergency medicine》2018,36(8):1528.e1-1528.e2
Fluoroquinolones, including levofloxacin, exhibit desirable antimicrobial characteristics, including broad spectrum of activity and excellent bioavailability. This widely prescribed class of antibiotics has come under scrutiny due to a new black box warning of adverse reactions. Central nervous system effects have been sparsely described in previous literature. We present a case of levofloxacin-induced psychosis in a patient without underlying psychological history. 相似文献
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