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排序方式: 共有475条查询结果,搜索用时 15 毫秒
101.
祛白酊质量标准的实验研究 总被引:1,自引:0,他引:1
目的:建立祛白酊的质量标准。方法:采用薄层色谱法鉴别其中的补骨脂素,异补骨脂素,栀子苷;导数分光光度法测定其中醋酸氢化可的松的含量。结果;薄层色谱鉴别方法有良好的重现性,专属性;醋酸氢化可的松在11-19ug.ml^-1呈良好的线性关系(r=0.9996)其含量测定平均回收率100.9%,RSD=0.9%(n=5)。结论:制定的质量标准可以保证祛白酊的质量。 相似文献
102.
103.
Percutaneous drainage access: a simplified coaxial technique 总被引:1,自引:0,他引:1
vanSonnenberg E; Wittich GR; Schiffman HR; Cabrera OA; Willson SA; Quinn SF; Casola G; Hayne LA; Polansky AD 《Radiology》1986,159(1):266-268
We describe an access technique that we have used in 150 nephrostomy and biliary drainage procedures and for access to some abscesses and viscera. The system provides safe coaxial access with a 22-gauge removable hub needle, which then acts as a guide wire and is replaced by an 18-gauge cannula. A major advantage is that only one guide wire is used (0.038-inch) for the entire drainage procedure. No significant complications have occurred to date with this method. 相似文献
104.
Complex orofacial movements and the disappearance of cerebellar mutism: report of five cases 总被引:1,自引:0,他引:1
Marijke van Mourik MA. Coriene E. Catsman-Berrevoets MD PhD Hugo R. van Dongen PhD Brian GR Neville 《Developmental medicine and child neurology》1997,39(10):686-690
A syndrome of mutism and subsequent dysarthria occurs frequently in children after resection of a cerebellar tumour. The role of orofacial and speech motor control in this syndrome has not been studied systematically. We examined simple and complex orofacial movements during the mute phase and shortly after the resumption of speech in five children with mutism and subsequent dysarthria. The recovery of complex orofacial movements coincided with the disappearance of the mutism 相似文献
105.
Interleukin-5 is at 5q31 and is deleted in the 5q- syndrome 总被引:3,自引:0,他引:3
Sutherland GR; Baker E; Callen DF; Campbell HD; Young IG; Sanderson CJ; Garson OM; Lopez AF; Vadas MA 《Blood》1988,71(4):1150-1152
Human interleukin-5 (IL-5) is a selective eosinophilopoietic and eosinophil-activating growth hormone. By in situ hybridization this gene is mapped to chromosome 5q23.3 to 5q32. It is shown to be deleted in two patients with the 5q-syndrome and in one patient previously diagnosed with myelodysplasia whose condition had progressed to acute myeloblastic leukemia. The clustering of other genes involved in hematopoiesis (IL-3, granulocyte-macrophage colony-stimulating factor, feline sarcoma viral oncogene homolog, colony-stimulating factor 1) to the same region as IL-5 suggests a nonrandom localization and raises interesting questions concerning the evolution and regulation of these genes. 相似文献
106.
107.
BACKGROUND: The Consultation Quality Index (CQI) is a holistic quality marker for GPs based on patient enablement, continuity of the care and consultation length. AIM: To evaluate the CQI-2, a new version of the CQI incorporating a process measure of GP empathy (the Consultation and Relational Empathy Measure). DESIGN OF STUDY: Cross-sectional questionnaire study. SETTING: General practice in the west of Scotland. METHOD: Empathy, enablement, continuity, and consultation length were measured in 3044 consultations involving 26 GPs in 26 different practices in the west of Scotland. CQI-2 scores were calculated and correlated with additional data on GPs' and patients' attitudes. Comparisons were also made with the UK-wide data from which the original CQI had been calculated. RESULTS: CQI-2 scores were independent of deprivation, access, demographics, and case-mix. GPs with lower CQI-2 scores valued empathy and longer consultations less than these GPs with higher CQI-2 scores. 'Below average CQI-2' GPs (those in the bottom 25%) also felt less valued by patients and colleagues. Patients' showed less confidence in and gained less satisfaction from these doctors. Data ranges from the study were comparable with the UK data ranges used to construct the original CQI. CONCLUSIONS: The CQI-2 is a new measure of holistic interpersonal care. In a small but representative sample of GPs it appears to differentiate between below and above average doctors. CQI-2 scores may reflect important aspects of morale, core values and patient-centred care. There may be potential for its use as part of professional development and as a component of the general medical services contract. 相似文献
108.
Direct addition of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; 5-20 nM) to cultures of spleen cells from (C57BL/6 x C3H)F1 (B6C3F1) mice produced a suppression of the number of antibody-producing cells which developed in response to lipopolysaccharide, dinitrophenyl-Ficoll and sheep erythrocytes. The suppression of all three parameters was dose-related and parallel. This parallelism and the observation that the magnitude of the suppression was comparable in all three models suggested that the B-lymphocyte was the primary target. The defect was attributed to an effect on early activation or impaired differentiation because direct addition of TCDD had no effect on mitogen-induced proliferation. Temporal studies showed that TCDD produced the greatest suppression of the polyclonal antibody response to lipopolysaccharide when added at the beginning of the culture and that there was no suppression when TCDD was added as soon as 3 h after 200 micrograms/ml lipopolysaccharide. The observation that TCDD could directly suppress the antibody response by spleen cells from DBA/2 mice, at concentrations comparable to those required to suppress the B6C3F1 mice, suggested that the effect on the B-lymphocyte was atypical of the profile of activity (i.e., dependence on the Ah locus) previously reported to characterize the effects of dioxin in other systems. Similar results were demonstrated with congenic mice, as Ahd/d homozygotes were suppressed comparably to Ahb/d heterozygotes. The direct suppression by 2,7-dichlorodibenzo-p-dioxin, a congener previously demonstrated to be devoid of affinity for the Ah locus, further suggests a dissociation from the traditional profile of activity. 相似文献
109.
We report two cases in which the umbilical cords of fetuses were large on prenatal ultrasound scans. The pregnancies terminated uneventfully, however, and the babies were healthy at birth and on follow-up visits. We discuss the various etiologies of a large umbilical cord and conclude that, although a large cord may suggest the presence of an underlying abnormality, in some instances it may represent a normal finding. 相似文献
110.
Five factors have been shown to influence the 20-fold variation of fetal hemoglobin (Hb F) levels in sickle cell anemia (SS): age, sex, the alpha-globin gene number, beta-globin haplotypes, and an X-linked locus that regulates the production of Hb F-containing erythrocytes (F cells), ie, the F-cell production (FCP) locus. To determine the relative importance of these factors, we studied 257 Jamaican SS subjects from a Cohort group identified by newborn screening and from a Sib Pair study. Linear regression analyses showed that each variable, when analyzed alone, had a significant association with Hb F levels (P < .05). Multiple regression analysis, including all variables, showed that the FCP locus is the strongest predictor, accounting for 40% of Hb F variation. beta-Globin haplotypes, alpha-globin genes, and age accounted for less than 10% of the variation. The association between the beta-globin haplotypes and Hb F levels becomes apparent if the influence of the FCP locus is removed by analyzing only individuals with the same FCP phenotype. Thus, the FCP locus is the most important factor identified to date in determining Hb F levels. The variation within each FCP phenotype is modulated by factors associated with the three common beta-globin haplotypes and other as yet unidentified factor(s). 相似文献