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11.
José Wellington Alves dos Santos Fabiani Palagi Machado Felipe Schaich Douglas Zaione Nascimento Tiago Teixeira Simon Luis Fernando Cibin Keli Cristina Mann Vinícius André Guerra Mateus Correa Marcos Ferreira Gazzoni Marta Pires da Rocha Melissa Daubermann Falster Ronaldo Manfredini Vassoler 《Respiratory Medicine Extra》2007,3(4):186-188
12.
Heloiza F. O. Silva Rayane P. de Lima Fernanda S. L. da Costa Edgar P. Moraes Maria C. N. Melo Celso SantAnna Mateus Eugênio Luiz H. S. Gasparotto 《RSC advances》2018,8(42):23578
In a previous paper (RSC Adv., 2015, 5, 66886–66893), we showed that the combination of silver nanoparticles (NanoAg) with doxycycline (DO) culminated in an increased bactericidal activity towards E. coli. Herein we further investigated the metabolic changes that occurred on Staphylococcus aureus upon exposure to NanoAg with the help of attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) coupled with multivariate data analysis. It has been discovered that the combination of DO with NanoAg produced metabolic changes in S. aureus that were not simply the overlap of the treatments with DO and NanoAg separately. Our results suggest that DO and NanoAg act synergistically to impede protein synthesis by the bacteria.Silver nanoparticles conjugated with doxycycline act synergistically to halt S. aureus growth via inhibition of protein synthesis. 相似文献
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José Aderval Aragão Maria Luisa Silveira Souto Carla Rocha São Mateus Liciane dos Santos Menezes Francisco Prado Reis 《Surgical and radiologic anatomy : SRA》2014,36(9):889-894
Purpose
The human mandible is subject to stimuli during its growth phase and also in adulthood. One of these stimuli may be absence of teeth, which gives rise to mandibular remodeling. Morphological changes may occur in different areas of this bone, such as in the gonial, condylar and ramus regions.Objective
To investigate the influence of edentulousness on remodeling of the gonial angle of the mandible and the angle formed by the mandibular incisure.Materials and method
Eighty-five dry mandibles from adults were examined: 42 from males and 43 from females. The mandibles were photographed using a camera coupled to a static support that was positioned 20 cm from the object to be photographed. The images were digitized and transferred to the Image J 1.42q software, in which the gonial angle of the mandible and the mandibular incisure angle were measured.Results
There were no differences in the mandibular and mandibular incisure angles in relation to presence or absence of teeth, or between the right and left sides. The mandibular incisure angle was greater in the women.Conclusion
Edentulousness did not cause remodeling of the gonial angle of the mandible or in the mandibular incisure angle. 相似文献15.
Pizzaia Daniel Nogueira Marina Lima Mondin Mateus Carvalho Marcia Eugenia Amaral Piotto Fernando Angelo Rosario Millor Fernandes Azevedo Ricardo Antunes 《Ecotoxicology (London, England)》2019,28(9):1046-1055
Ecotoxicology - This study aimed to investigate the mode of action of cadmium (Cd) toxicity at cell level, especially at early stages of plant exposure. Tomato seedlings were cultivated in growth... 相似文献
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Bertoldi EG Severo MD Scheffel RS Foppa M de Azevedo MJ Maia AL 《Echocardiography (Mount Kisco, N.Y.)》2012,29(2):E30-E33
Intracardiac metastases of thyroid carcinoma are a rare event. Their incidence is low in large autopsy series, and antemortem diagnosis is even less common. We present the case of a woman with advanced poorly differentiated thyroid carcinoma who had extensive intracardiac metastases. This case highlights the usefulness of echocardiography and magnetic resonance imaging in the diagnosis and differential diagnosis of cardiac metastases. 相似文献
18.
Alana Pimentel Moura Mateus Grings Belisa dos Santos Parmeggiani Gustavo Flora Marcowich Anelise Miotti Tonin Carolina Maso Viegas Ângela Zanatta César Augusto João Ribeiro Moacir Wajner Guilhian Leipnitz 《Neurotoxicity research》2013,24(4):502-511
High tissue levels of glycine (GLY) are the biochemical hallmark of nonketotic hyperglycinemia (NKH), an inherited metabolic disease clinically characterized by severe neurological symptoms and brain abnormalities. Considering that the mechanisms underlying the neuropathology of this disease are not fully established, the present work investigated the in vivo effects of intracerebroventricular administration of GLY on important parameters of energy metabolism in cerebral cortex and striatum from young rats. Our results show that GLY reduced CO2 production using glucose as substrate and inhibited the activities of citrate synthase and isocitrate dehydrogenase in striatum, whereas no alterations of these parameters were verified in cerebral cortex 30 min after GLY injection. We also observed that GLY diminished the activities of complex IV in cerebral cortex and complex I–III in striatum at 30 min and inhibited complex I–III activity in striatum at 24 h after its injection. Furthermore, GLY reduced the activity of total and mitochondrial creatine kinase in both brain structures 30 min and 24 h after its administration. In contrast, the activity of Na+, K+-ATPase was not altered by GLY. Finally, the antioxidants N-acetylcysteine and creatine, and the NMDA receptor antagonist MK-801 attenuated or fully prevented the inhibitory effects of GLY on creatine kinase and respiratory complexes in cerebral cortex and striatum. Our data indicate that crucial pathways for energy production and intracellular energy transfer are severely compromised by GLY. It is proposed that bioenergetic impairment induced by GLY in vivo may contribute to the neurological dysfunction found in patients affected by NKH. 相似文献
19.
Braga NM Silva JM Carvalho-Júnior JR Ferreira RC Saquy PC Brito-Júnior M 《Brazilian dental journal》2012,23(1):49-53
This in vitro study compared different ultrasonic vibration modes for intraradicular cast post removal. The crowns of 24 maxillary canines were removed, the roots were embedded in acrylic resin blocks, and the canals were treated endodontically. The post holes were prepared and root canal impressions were taken with self-cured resin acrylic. After casting, the posts were cemented with zinc phosphate cement. The samples were randomly distributed into 3 groups (n=8): G1: no ultrasonic vibration (control); G2: tip of the ultrasonic device positioned perpendicularly to core surface and close to the incisal edge; and G3: tip of the ultrasonic device positioned perpendicularly to core surface at cervical region, close to the line of cementation. An Enac OE-5 ultrasound unit with an ST-09 tip was used. All samples were submitted to the tensile test using an universal testing machine at a crosshead speed of 1 mm/min. Data were subjected to one-way ANOVA and Tukey's post-hoc tests (α=0.05). Mean values of the load to dislodge the posts (MPa) were: G1 = 4.6 (± 1.4) A; G2 = 2.8 (± 0.9) B, and G3= 0.9 (± 0.3) C. Therefore, the ultrasonic vibration applied with the tip of device close to the core's cervical area showed higher ability to reduce the retention of cast post to root canal. 相似文献
20.
Vitor Massaro Takamatsu Sagae Igor Braga Ribeiro Diogo Turiani Hourneaux de Moura Vitor Ottoboni Brunaldi Fernanda Prado Logiudice Mateus Pereira Funari Elisa Ryoka Baba Wanderley Marques Bernardo Eduardo Guimares Hourneaux de Moura 《Surgical endoscopy》2020,34(3):1025-1034
Minimally invasive treatment of early-stage rectal lesion has presented good results, with lower morbidity than surgical resection. Transanal endoscopic microsurgery (TEM) and transanal minimally invasive surgery (TAMIS) are the main methods of transanal surgery. However, endoscopic submucosal dissection (ESD) has been gaining ground because it allows en bloc resections with low recurrence rates. The aim of this study was to analyze ESD in comparison with transanal endoscopic surgery. We searched MEDLINE, EMBASE, SciELO, Cochrane CENTRAL, and Lilacs/Bireme with no restrictions on the date or language of publication. The outcomes evaluated were recurrence rate, complete (R0) resection rate, en bloc resection rate, length of hospital stay, duration of the procedure, and complication rate. Six retrospective cohort studies involving a collective total of 326 patients—191 in the ESD group and 135 in the transanal endoscopic surgery group were conducted. There were no statistically significant differences between the groups for any of the outcomes evaluated. For the minimally invasive treatment of early rectal tumor, ESD and surgical techniques do not differ in terms of local recurrence, en bloc resection rate, R0 resection rate, duration of the procedure, length of hospital stay, or complication rate, however, evidence is very low. 相似文献