全文获取类型
收费全文 | 831102篇 |
免费 | 56541篇 |
国内免费 | 2161篇 |
专业分类
耳鼻咽喉 | 10858篇 |
儿科学 | 26123篇 |
妇产科学 | 19854篇 |
基础医学 | 126432篇 |
口腔科学 | 22126篇 |
临床医学 | 76305篇 |
内科学 | 159964篇 |
皮肤病学 | 18353篇 |
神经病学 | 61157篇 |
特种医学 | 31007篇 |
外国民族医学 | 79篇 |
外科学 | 124005篇 |
综合类 | 16345篇 |
现状与发展 | 2篇 |
一般理论 | 304篇 |
预防医学 | 60529篇 |
眼科学 | 19157篇 |
药学 | 62708篇 |
3篇 | |
中国医学 | 2790篇 |
肿瘤学 | 51703篇 |
出版年
2021年 | 8298篇 |
2019年 | 8160篇 |
2018年 | 11158篇 |
2017年 | 8481篇 |
2016年 | 9557篇 |
2015年 | 10891篇 |
2014年 | 14920篇 |
2013年 | 21435篇 |
2012年 | 29951篇 |
2011年 | 31450篇 |
2010年 | 18508篇 |
2009年 | 17048篇 |
2008年 | 28512篇 |
2007年 | 30201篇 |
2006年 | 30242篇 |
2005年 | 28416篇 |
2004年 | 27605篇 |
2003年 | 25874篇 |
2002年 | 24972篇 |
2001年 | 37781篇 |
2000年 | 37999篇 |
1999年 | 31784篇 |
1998年 | 9258篇 |
1997年 | 7754篇 |
1996年 | 7862篇 |
1995年 | 7436篇 |
1994年 | 6798篇 |
1993年 | 6237篇 |
1992年 | 23661篇 |
1991年 | 23494篇 |
1990年 | 22861篇 |
1989年 | 22572篇 |
1988年 | 20507篇 |
1987年 | 19853篇 |
1986年 | 18853篇 |
1985年 | 17719篇 |
1984年 | 13126篇 |
1983年 | 11087篇 |
1982年 | 6310篇 |
1979年 | 11725篇 |
1978年 | 8327篇 |
1977年 | 6987篇 |
1976年 | 6703篇 |
1975年 | 7375篇 |
1974年 | 8602篇 |
1973年 | 8255篇 |
1972年 | 7749篇 |
1971年 | 7194篇 |
1970年 | 6940篇 |
1969年 | 6358篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
A. Guerrero Gómez N. González Jaramillo J.A. Castro Pérez 《Revista espa?ola de anestesiología y reanimación》2019,66(1):10-17
Introduction
The fast track / ultra-fast-track protocols are techniques used to optimise the patient care process and a quick recovery after cardiac surgery. They are one of the mainstays of efficient practice. With their use, the length of hospital and intensive care unit (ICU) stays are reduced, with a direct impact on costs and the quality of the health service.Objective
To compare the length of stay in the ICU, length of hospital stay, and post-operative mortality in ultra-fast-track extubated (uFTE) patients and those with conventional extubation (CE) after cardiac surgery.Methods
Longitudinal, analytical, retrospective study was conducted, with the period between the time of surgery and discharge being included as the study period.Results
A total of 396 patients older than 18 years who required cardiac surgery were included, of whom 207 patients had (uFTE) and 189 had CE. Although the groups were not comparable due to the statistical differences found, when performing the multivariate adjustment, uFTE maintained its statistical independence and was associated with lower cardiovascular morbidity, such as myocardial ischaemia (95% CI: 0.37-0.86; P = .01) and lower post-surgical vasopressor requirement (95% CI: 0.18-0.49; P < .01). No significant differences were found in the length of hospital stay, ICU stay, or post-operative mortality in the ICU.Conclusion
Implementing the uFTE strategy, decreases cardiovascular morbidity and vasopressor requirement. The change to uFTE should be accompanied by changes in models and practices in patient recovery to standardised protocols. This study shows that uFTE did not reduce the length of ICU stay, hospital stay, or mortality. 相似文献72.
The cingulum, connecting the orbitofrontal cortex to the medial temporal lobe, involves in diverse cognition functions including attention, memory, and motivation. To investigate the relationship between the cingulum injury and cognitive impairment in patients with chronic mild traumatic brain injury, we evaluated the integrity between the anterior cingulum and the basal forebrain using diffusion tensor tractography in 73 patients with chronic mild traumatic brain injury(39 males, 34 females, age 43.29 ± 11.42 years) and40 healthy controls(22 males, 18 females, age 40.11 ± 16.81 years). The patients were divided into three subgroups based on the integrity between the anterior cingulum and the basal forebrain on diffusion tensor tractography: subgroup A(n = 19 patients)-both sides of the anterior cingulum were intact; subgroup B(n= 36 patients)-either side of the anterior cingulum was intact; and subgroup C(18 patients)-both sides of the anterior cingulum were discontinued. There were significant differences in total Memory Assessment Scale score between subgroups A and B and between subgroups A and C. There were no significant differences in diffusion tensor tractography parameters(fractional anisotropy, apparent diffusion coefficient, and fiber volume) between patients and controls. These findings suggest that the integrity between the anterior cingulum and the basal forebrain, but not diffusion tensor tractography parameter, can be used to predict the cognitive function of patients with chronic mild traumatic brain injury. This study was approved by Yeungnam University Hospital Institutional Review Board(approval No. YUMC-2014-01-425-010) on August 16, 2017. 相似文献
73.
Hae June Lee Yeonghoon Son Minyoung Lee Changjong Moon Sung Ho Kim In Sik Shin Miyoung Yang Sangwoo Bae Joong Sun Kim 《中国神经再生研究》2019,(9)
Sodium butyrate is a histone deacetylase inhibitor that affects various types of brain damages. To investigate the effects of sodium butyrate on hippocampal dysfunction that occurs after whole-brain irradiation in animal models and the effect of sodium butyrate on radiation exposure-induced cognitive impairments,adult C57BL/6 mice were intraperitoneally treated with 0.6 g/kg sodium butyrate before exposure to 10 Gy cranial irradiation. Cognitive impairment in adult C57BL/6 mice was evaluated via an object recognition test 30 days after irradiation. We also detected the expression levels of neurogenic cell markers(doublecortin)and phosphorylated cAMP response element binding protein/brain-derived neurotrophic factor. Radiation-exposed mice had decreased cognitive function and hippocampal doublecortin and phosphorylated cAMP response element binding protein/brain-derived neurotrophic factor expression. Sodium butyrate pretreatment reversed these changes. These findings suggest that sodium butyrate can improve radiation-induced cognitive dysfunction through inhibiting the decrease in hippocampal phosphorylated cAMP response element binding protein/brain-derived neurotrophic factor expression. The study procedures were approved by the Institutional Animal Care and Use Committee of Korea Institute of Radiological Medical Sciences(approval No. KIRAMS16-0002) on December 30, 2016. 相似文献
74.
Éktova L. V. Goryunova O. V. Eremina V. A. Tikhonova N. I. Medvedeva L. A. 《Pharmaceutical Chemistry Journal》2019,53(7):604-609
Pharmaceutical Chemistry Journal - Use of formylindolylacetic acid as a reagent at the stage of preparing the glycosides of bis(indolyl)furan-2,5-diones and dioxane as solvent increased yields from... 相似文献
75.
76.
77.
78.
79.
80.