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The older patient's experience of the healthcare chain and information when undergoing colorectal cancer surgery according to the enhanced recovery after surgery concept 下载免费PDF全文
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An interview‐based study of nonattendance at screening for cardiovascular diseases and diabetes in older women: Nonattendees’ perspectives 下载免费PDF全文
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Marie Rippingale 《Veterinary Nursing Journal》2018,33(5):148-151
As a Registered Equine Veterinary Nurse (REVN), Marie had always been interested in equine welfare. In 2015, she flew out to The Gambia, Africa to work at The Gambia Horse and Donkey Trust (GHDT). The REVN spend two weeks at GHDT helping to look after inpatients, treat horses and donkeys out on visits and at markets. This article focuses on Marie’s second trip out to GHDT in December 2017 and demonstrates that it is both challenging and rewarding for a REVN to go abroad, and share skills and knowledge, to help animals and owners in need. 相似文献
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Possible role of CYP2B6 genetic polymorphisms in ifosfamide‐induced encephalopathy: report of three cases 下载免费PDF全文
Thomas Duflot Aude Marie‐Cardine Céline Verstuyft Bruno Filhon Tony Pereira Nathalie Massy‐Guillemant Robinson Joannidès Jérémy Bellien Fabien Lamoureux 《Fundamental & clinical pharmacology》2018,32(3):337-342
Ifosfamide (IFA) is a potent alkylating antitumoral agent, but its use is limited by neurological side effects. IFA is a racemic mixture of two enantiomeric forms, R‐IFA and S‐IFA with a stereoselective metabolism by CYP3A4 and CYP2B6, leading either to bioactive or to toxic pathways. In three consecutive cases of pediatric patients who exhibited IFA‐induced encephalopathy (IIE), genotyping of clinically relevant single‐nucleotide polymorphisms associated with decreased CYP3A4 and CYP2B6 activities was performed. Genetic investigations revealed the presence of CYP2B6 rs4803419 (C>T) in one patient while the two others carried the CYP2B6*6 allelic variant. All patients carried CYP3A4 wild‐type genotype (CYP3A4*1/*1). Because CYP2B6‐deficient alleles may be responsible for an increased conversion of S‐IFA into neurotoxic metabolites, screening for CYP2B6 polymorphisms may help to avoid IIE and improve clinical outcomes. 相似文献
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Lynere Wilson RN PhD Marie Crowe RN PhD Anne Scott PhD Cameron Lacey FRANZCP PhD 《International journal of mental health nursing》2018,27(1):349-357
Psychoeducation has become a common intervention within mental health settings. It aims to increase people's ability to manage a life with a long‐term illness. For people with bipolar disorder, psychoeducation is one of a range of psychosocial interventions now considered part of contemporary mental health practice. It has taken on a ‘common sense’ status that results in little critique of psychoeducation practices. Using a published manual on psychoeducation and bipolar disorder as its data, Foucauldian discourse analysis was used in the present study for a critical perspective on psychoeducation in order to explore the taken‐for‐granted assumptions on which it is based. It identifies that the text produces three key subject positions for people with bipolar disorder. To practice self‐management, a person must: (i) accept and recognize the authority of psychiatry to know them; (ii) come to see that they can moderate themselves; and (iii) see themselves as able to undertake a reflexive process of self‐examination and change. These findings highlight the circular and discursive quality to the construct of insight that is central to how psychoeducation is practiced. Using Foucault's construct of pastoral power, it also draws attention to the asymmetrical nature of power relations between the clinician and the person with bipolar disorder. An effect of the use of medical discourse in psychoeducation is to limit its ability to work with ambivalence and contradiction. A critical approach to psychotherapy and education offers an alternate paradigm on which to basis psychoeducation practices. 相似文献
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Systemic allergic contact dermatitis caused by methyl aminolaevulinate in a patient with keratosis–ichthyosis–deafness syndrome 下载免费PDF全文
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