全文获取类型
收费全文 | 34472篇 |
免费 | 3680篇 |
国内免费 | 122篇 |
专业分类
耳鼻咽喉 | 283篇 |
儿科学 | 1305篇 |
妇产科学 | 864篇 |
基础医学 | 4719篇 |
口腔科学 | 690篇 |
临床医学 | 4649篇 |
内科学 | 7122篇 |
皮肤病学 | 707篇 |
神经病学 | 3507篇 |
特种医学 | 876篇 |
外国民族医学 | 4篇 |
外科学 | 4041篇 |
综合类 | 574篇 |
一般理论 | 35篇 |
预防医学 | 3333篇 |
眼科学 | 472篇 |
药学 | 2450篇 |
中国医学 | 23篇 |
肿瘤学 | 2620篇 |
出版年
2023年 | 287篇 |
2022年 | 431篇 |
2021年 | 868篇 |
2020年 | 697篇 |
2019年 | 1051篇 |
2018年 | 1163篇 |
2017年 | 899篇 |
2016年 | 944篇 |
2015年 | 1010篇 |
2014年 | 1303篇 |
2013年 | 1781篇 |
2012年 | 2266篇 |
2011年 | 2183篇 |
2010年 | 1364篇 |
2009年 | 1247篇 |
2008年 | 1931篇 |
2007年 | 1976篇 |
2006年 | 1822篇 |
2005年 | 1775篇 |
2004年 | 1659篇 |
2003年 | 1495篇 |
2002年 | 1377篇 |
2001年 | 627篇 |
2000年 | 563篇 |
1999年 | 561篇 |
1998年 | 374篇 |
1997年 | 284篇 |
1996年 | 257篇 |
1995年 | 255篇 |
1994年 | 228篇 |
1993年 | 215篇 |
1992年 | 375篇 |
1991年 | 353篇 |
1990年 | 350篇 |
1989年 | 324篇 |
1988年 | 309篇 |
1987年 | 298篇 |
1986年 | 303篇 |
1985年 | 285篇 |
1984年 | 231篇 |
1983年 | 206篇 |
1982年 | 196篇 |
1981年 | 170篇 |
1980年 | 122篇 |
1979年 | 147篇 |
1976年 | 146篇 |
1975年 | 123篇 |
1974年 | 133篇 |
1973年 | 141篇 |
1972年 | 119篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
C. Noonan M. Farrell J. Mullaney H. Cassidy M. A. Asghar B. J. Young Marie Hickey-Dwyer A. Patterson W. Power M. Hillery A. Benedict-Smith L. M. T. Collum S. Fitzsimon E. O’Donoghue R. Hitchings G. B. Arden A. O’Mahony A. Murray A. Whyte M. Shehata Hugh O’Donoghue Rosemary Robinson J. Toland P. Eustace 《Irish journal of medical science》1991,160(10):322-324
102.
103.
104.
105.
British Thoracic Society study of cryptogenic fibrosing alveolitis: current presentation and initial management. Fibrosing Alveolitis Subcommittee of the Research Committee of the British Thoracic Society 总被引:9,自引:3,他引:6 下载免费PDF全文
BACKGROUND: Mortality due to cryptogenic fibrosing alveolitis (CFA) is increasing, particularly in the elderly. Optimum management remains uncertain and previous studies of the disease have largely been from specialist centres. A national study was carried out of the presentation and initial management of CFA in the UK. METHODS: All respiratory physicians in England, Scotland and Wales were invited to enter patients with newly diagnosed CFA over a two year period. CFA was diagnosed on histological grounds or according to clinical criteria which included the absence of a defined connective tissue disorder or pneumoconiosis. Participating physicians (n = 150) completed a questionnaire at patient entry and at all subsequent follow up visits and death. RESULTS: A total of 588 patients (373 men, 63%) were studied of whom 441 (75%) were referrals from primary care. Their mean (SD) age was 67.4 (10.0) years and median duration of symptoms at presentation was 9.0 months. Clubbing was more common in men (203/373; 54%) than in women (86/ 215; 40%); 209 patients (36%) were graded as severely breathless at presentation. A history of dust exposure (organic or inorganic) was present in 274 patients (47%) of whom 87 had had some exposure to asbestos. Subjects exposed to dust were more likely to have smoked and had slightly higher mean lung volumes, but were otherwise indistinguishable from those not exposed in terms of clinical presentation, management, and outcome. Transbronchial biopsy specimens were taken in 164 patients (28%) and open lung biopsy specimens in 73 (12%), but 60% had no histological diagnostic procedure. Biopsy procedures were more likely to be performed in younger patients, those with better lung function, and those with a history of asbestos exposure. At presentation a decision not to initiate specific treatment was made in 284 cases (48%). The decision to initiate treatment was made predominantly on symptomatic grounds. Two years after the close of entry to the study 266 patients (45%) had died. CONCLUSIONS: CFA is predominantly a disease of elderly patients and has a poor prognosis. Physicians generally considered CFA to be a clinical diagnosis and did not initiate treatment in up to half of patients at presentation.
相似文献
相似文献
106.
P D Clouston C B Saper T Arbizu I Johnston B Lang J Newsom-Davis J B Posner 《Neurology》1992,42(10):1944-1950
We studied nine patients with a subacute onset of a pancerebellar syndrome. Six had known cancer (three small-cell carcinoma of the lung [SCLC], one metastatic small-cell carcinoma, one small-cell carcinoma of the prostate, and one non-Hodgkin's lymphoma). Six of eight who had neurophysiologic testing, including the three patients without detectable cancer, had coexistent Lambert-Eaton myasthenic syndrome (LEMS). In two of the patients, LEMS was discovered only by neurophysiologic testing. We looked for anti-Purkinje cell autoantibodies in all patient's sera and in four patients' CSF. We also looked for autoantibodies to voltage-gated calcium channels (VGCCs) in seven patients' sera and two patients' CSF, using the 125I-omega-conotoxin radioimmunoassay. We were unable to detect anti-Purkinje cell autoantibodies in any patients' serum or CSF. However, there were raised titers of anti-VGCC autoantibodies in five of seven patients' serum, including one patient with SCLC who did not have LEMS, and in the CSF of one of two patients. We conclude that the frequency of presentation of a pancerebellar syndrome with LEMS is higher than expected by chance and is usually associated with cancer. In some of these patients, LEMS may be clinically occult. The presence of LEMS and raised titers of anti-VGCC autoantibodies in some patients with subacute cerebellar degeneration is suggestive of an autoimmune etiology even though anti-Purkinje cell antibodies could not be detected. Anti-VGCC autoantibodies are not confined to LEMS. They may be found at high titer in CSF as well as serum. 相似文献
107.
Brian F O'Donnell Marcia A Wilt Ann Marie Hake Julie C Stout Sandra C Kirkwood Tatiana Foroud 《Movement disorders》2003,18(9):1027-1034
Disturbances of visual cognition, visuomotor performance, and visual memory have been described frequently in Huntington's disease (HD). Early stage visual abnormalities could contribute to these deficits. We evaluated visual processing in 20 control subjects who were non-gene carriers at risk for HD, nine presymptomatic gene-positive subjects, and eight subjects with a recent diagnosis of Huntington's disease. Visual perceptual tests of contrast sensitivity and motion discrimination were used to probe early stage visual processing. Extraocular movements were evaluated in a neurologic examination, and the Digit Symbol test was used to test visual motor performance. Contrast sensitivity did not differ among the three groups. Motion discrimination was impaired in HD subjects but not in the presymptomatic gene carriers when compared to gene noncarriers. Among gene carriers, impaired motion discrimination performance was associated with poorer Digit Symbol performance and extraocular abnormalities. These findings suggest that the early stages of HD are associated with disturbances of motion perception as well as disruptions of visual motor and ocular motor performance. 相似文献
108.
109.
Christine Duffield Mark Kearin Judy Johnston Joanna Leonard 《The Australian journal of advanced nursing》2007,24(4):42-46
OBJECTIVE: Health systems throughout much of the world have been subject to 'reform' in recent years as countries have attempted to contain the rapidly rising costs of health care. Changes to hospital structures (restructuring) have been an important part of these reforms. A significant impact of current approaches to restructuring is the loss of, or changes to, nursing management roles and functions. SETTING: Australian hospitals PRIMARY ARGUMENT: Little evaluation has been undertaken to determine the impact of hospital structure and organisational restructuring on the nursing workforce. CONCLUSIONS: There is some indication that nurses have experienced a loss of key management positions, which may impact on their capacity to ensure that adequate and safe care is provided at the ward level. 相似文献
110.