全文获取类型
收费全文 | 35446篇 |
免费 | 2200篇 |
国内免费 | 270篇 |
专业分类
耳鼻咽喉 | 458篇 |
儿科学 | 653篇 |
妇产科学 | 559篇 |
基础医学 | 4383篇 |
口腔科学 | 1566篇 |
临床医学 | 2941篇 |
内科学 | 9587篇 |
皮肤病学 | 500篇 |
神经病学 | 3479篇 |
特种医学 | 1415篇 |
外科学 | 5551篇 |
综合类 | 102篇 |
一般理论 | 6篇 |
预防医学 | 1489篇 |
眼科学 | 590篇 |
药学 | 1892篇 |
中国医学 | 73篇 |
肿瘤学 | 2672篇 |
出版年
2024年 | 33篇 |
2023年 | 368篇 |
2022年 | 688篇 |
2021年 | 1291篇 |
2020年 | 763篇 |
2019年 | 1045篇 |
2018年 | 1247篇 |
2017年 | 985篇 |
2016年 | 1103篇 |
2015年 | 1161篇 |
2014年 | 1508篇 |
2013年 | 1846篇 |
2012年 | 2885篇 |
2011年 | 2788篇 |
2010年 | 1569篇 |
2009年 | 1425篇 |
2008年 | 2250篇 |
2007年 | 2379篇 |
2006年 | 2145篇 |
2005年 | 1936篇 |
2004年 | 1740篇 |
2003年 | 1594篇 |
2002年 | 1399篇 |
2001年 | 369篇 |
2000年 | 337篇 |
1999年 | 322篇 |
1998年 | 274篇 |
1997年 | 218篇 |
1996年 | 185篇 |
1995年 | 162篇 |
1994年 | 149篇 |
1993年 | 123篇 |
1992年 | 190篇 |
1991年 | 153篇 |
1990年 | 123篇 |
1989年 | 105篇 |
1988年 | 136篇 |
1987年 | 109篇 |
1986年 | 79篇 |
1985年 | 102篇 |
1984年 | 70篇 |
1983年 | 56篇 |
1982年 | 52篇 |
1981年 | 44篇 |
1980年 | 34篇 |
1979年 | 58篇 |
1978年 | 39篇 |
1974年 | 30篇 |
1973年 | 39篇 |
1972年 | 31篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
52.
53.
Papillary thyroid microcarcinomas (PTMs) are small tumors (< or =1 cm of diameter) that belong to the well-differentiated low-risk carcinomas of the thyroid, which are characterized by benign behavior, probably of little clinical significance, and do not affect patients' survival. They are found in otherwise normal thyroids or in multinodular goiters with a clinical frequency varying substantially according to different series. Sometimes, PTM may be associated with lymph node metastases at presentation and/or locoregional recurrences during follow-up. Distant metastases are extremely rare, but have been reported. Although deaths related to PTM are almost unknown, PTM raises therapeutic implications. This review addresses the issue of definition, treatment, and follow-up of PTM. 相似文献
54.
Plaque composition and its relationship with acknowledged shear stress patterns in coronary arteries. 总被引:2,自引:0,他引:2
55.
Image fusion of bone SPECT and CT - a specific diagnostic method in oral and maxillofacial surgery] 总被引:1,自引:0,他引:1
Denys John Loeffelbein Marco Rainer Kesting Eckhart Mielke Margot Jonas Frank H?lzle Klaus-Dietrich Wolff 《Mund-, Kiefer- und Gesichtschirurgie》2007,11(1):33-41
OBJECTIVE: The aim of this study was to evaluate the benefit of image fusion of CT (computertomography) and bone SPECT (single photon emission computed tomography) in diagnosis of head and neck cancer. METHODS AND PATIENTS: Computer based image fusion has been applied in 39 patients with suspected cancer in the oromaxillofacial region following CT and SPECT without any further hazard for the patients. Afterwards image fusion was set in comparision to simultaneously evaluation of CT and SPECT and histological findings. RESULTS: In 5 out of 39 patients SPECT/CT image fusion obtained more precise anatomical findings in tumour expansion than simultaneously evaluation of CT and SPECT. CONCLUSION: For planning of surgical and radiation therapy of oral and maxillofacial cancer, image fusion of CT/SPECT provides efficient and plastical diagnostic imaging. Particularly in complex anatomical regions like maxilla or base of the skull image fusion could be an additional device, if simultaneous evaluation of CT and SPECT is not clear. 相似文献
56.
Marco Cirillo Andrea Amaducci Emmanuel Villa Margherita Dalla Tomba Federico Brunelli Zen Mhagna Giovanni Troise Eugenio Quaini 《Journal of cardiothoracic surgery》2006,1(1):40-11
Background
Long-term morphofunctional outcome may vary widely in surgical anterior left ventricular wall restoration, suggesting variability in post-surgical remodeling similar to that observed following acute myocardial infarction. The aim of this pilot study was to demonstrate that surgical restoration obtained with a particular shape of endoventricular patch leads to steady morphofunctional ventricular improvement when geometry, volume and residual akinesia can be restored as normal as possible. 相似文献57.
Schistosoma mansoni infection, both in humans and in animal models, is known to induce granulomas in the liver and intestine. It has also been
reported that in humans the eggs of this parasite can reach the brain, causing psychiatric and neuropathological disorders.
Whether this also occurs in rodents is unknown. To answer this question, mice were infected with this parasite and the central
nervous system (CNS) examined at various time intervals. The results show that schistosomiasis induced granulomas in several
regions of the CNS and increased nerve growth factor (NGF) levels in the cortex, hypothalamus and brain stem, but not in the
hippocampus. The infection also caused paw hyperalgesia, as determined by the hot-plate test, and a local increase in NGF,
but not in substance P. These findings indicate that the murine model of infection can be used for studying mechanisms leading
to human neuroschistosomiasis and suggest that the neuropathological disorders and the sensory deficits observed in human
schistosomiasis are associated with impaired levels of NGF in the peripheral and central nervous system.
Received: 18 January 1996 / Revised, accepted: 16 April 1996 相似文献
58.
Transient right-to-left shunting through a patent foramen ovale secondary to unilateral diaphragmatic paralysis. 总被引:1,自引:0,他引:1 下载免费PDF全文
P J Cordero P Morales V Mora J Cebrian J Vallterra J Gudin E Benlloch V Marco 《Thorax》1994,49(9):933-934
A 57 year old patient presented with unilateral diaphragmatic paralysis and severe hypoxaemia secondary to transient right-to-left interatrial shunting through a patent foramen ovale. The final diagnosis was made because of the initial detection of a shunt while the patient was breathing 100% oxygen. 相似文献
59.
60.
Antinori Andrea Cingolani Antonella Lorenzini Patrizia Giancola Maria Letizia Uccella Ilaria Bossolasco Simona Grisetti Susanna Moretti Francesca Vigo Beniamino Bongiovanni Marco Del Grosso Bruno Arcidiacono Maria Irene Fibbia Giovanni Carlo Mena Maurizio Finazzi Maria Grazia Guaraldi Giovanni Ammassari Adriana Monforte Antonella dArminio Cinque Paola De Luca Andrea 《Journal of neurovirology》2003,9(1):47-53
Human immunodeficiency virus (HIV)-associated progressive multifocal leukoencephalopathy (PML) remains a relevant clinical problem even in the era of highly active antiretroviral therapy (HAART). Aims of the study were to analyze clinical and treatment-related features and the survival probability of PML patients observed within the Italian Registry Investigative Neuro AIDS (IRINA) during a 29-month period of HAART. Intravenous drug use, the presence of focal signs, and the involvement of white matter at neuroradiology increased the risk of having PML. A reduced probability of PML was observed when meningeal signs were reported. Patients starting HAART at PML diagnosis and previously naïve for antiretrovirals showed significantly higher 1-year probability of survival (.58), compared to those continuing HAART (.24), or never receiving HAART (.00). Higher CD4 cell count were associated with a higher survival probability (.45). At multivariate analysis, a younger age, higher CD4, starting HAART at PML diagnosis, the absence of previous acquired immunodeficiency syndrome (AIDS)-defining events, and the absence of a severe neurologic impairment were all associated with a reduced hazard of death. The use of cidofovir showed a trend towards a reduced risk of death. 相似文献