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101.
Kashani Bahareh Zandi Zahra Bashash Davood Zaghal Azam Momeny Majid Poursani Ensieh M. Pourbagheri-Sigaroodi Atieh Mousavi Seyed A. Ghaffari Seyed H. 《Cancer chemotherapy and pharmacology》2020,85(1):47-59
Cancer Chemotherapy and Pharmacology - Despite all advances in the treatment of ovarian cancer (OC), it remains the most lethal gynecological malignancy worldwide. There are growing amounts of... 相似文献
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The effects of norepinephrine microinjected into the anterior hypothalamus were examined in feline affective defense behavior elicited by electrical stimulation of the region of the ventromedial nucleus. Anterior hypothalamic sites from which affective defense behavior could also be elicited by electrical stimulation and which are known to receive inputs from both the ventromedial nucleus and brainstem noradrenergic neurons were selected for pharmacological analysis. Intracerebral injections of 250 ng (1 nM) and 500 ng (2 nM) quantities of norepinephrine placed into the anterior hypothalamus resulted in a significant lowering of the attack thresholds. These reductions in response thresholds which were reversed by either pre- or post-treatment with yohimbine, indicate that the noradrenergic system may play an important role in the regulation of affective defense behavior. 相似文献
103.
Moath Zuhour Majid Ismayilzade Mehmet Dadac Bilsev Ince 《Indian Journal of Plastic Surgery》2022,55(1):58
Aim Several health problems have been reported to be triggered or facilitated by prolonged mask usage during the coronavirus disease 2019 (COVID-19) pandemic. While wearing a face mask, people tend to push their jaws forward and downward in a repetitive manner to hold their masks in the right position; these jaw motions may induce temporomandibular joint disorder (TMD). In this study, we aimed to investigate these repetitive jaw movements while wearing face masks and their effects on TMD. Patients and Methods Patients who applied with TMD signs between June 2020 and May 2021 were evaluated prospectively. A survey using a questionnaire was conducted to define patients with TMD that caused only by mask-related repetitive jaw movements. Demographic data (age and gender), mean duration of daily mask usage, mask type, and magnetic resonance imaging results were recorded. Results Prolonged daily mask usage (≥8 hours/day) was significantly higher in patients with mask-related habits (group a) with a rate of 40.4% ( p ≈ 0.001). Also, in this group, the disc displacement with reduction rate (54.6%) was higher compared with other groups ( p ≈ 0.010). On the contrary, patients with no underlying risk factor (group c) showed an unexpected high osteoarthritis rate ( p ≈ 0.029). Conclusions In this study, we demonstrate that correcting the position of a face mask by repetitive jaw movements can increase the occurrence of TMD. Informing individuals wearing face masks about the risk of TMD and the importance of choosing the appropriate mask size according to the face shape are important issues to be addressed in the near future. 相似文献
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Introduction The management of the regional lymph nodes in penile cancer patients, particularly when these lymph nodes are impalpable,
remains controversial. Prophylactic bilateral inguinal lymphadenectomy is associated with high morbidity and is often unnecessary.
However, there is no non-invasive or minimally invasive staging technique that can determine the lymph node status of penile
cancer patients with 100% accuracy.
Methods We reviewed the current literature to examine the role of non-invasive and minimally invasive techniques for staging regional
lymph nodes in penile cancer with particular reference to clinically impalpable disease.
Results Cross-sectional imaging (un-enhanced CT and MRI) modalities have a role in the assessment of patients with palpable inguinal
basins and in locating distant metastases, but are unreliable in staging impalpable regional lymph nodes. The spatial resolution
of lymphotropic nanoparticle enhanced MRI (LNMRI) and positron emission tomography (PET)/CT are limited to several millimetres
and so these modalities cannot reliably detect micro-metastases (<2 mm). Ultrasound (US) and fine-needle aspiration cytology
(FNAC) are indicated in staging palpable inguinal basins but are unreliable in isolation in the assessment of impalpable lymph
nodes. They are, however, useful as an adjunct to dynamic sentinel lymph node biopsy (DSLNB) in lowering false-negative rates.
Conclusions While we await staging modalities that can equal the results of DSLNB with fewer disadvantages, histological staging in the
form of DSLNB remains the best minimally invasive staging modality we can offer at risk patients presenting with clinically
node negative groins. 相似文献
106.
Dura to spinal cord distance at different vertebral levels in children and its implications on epidural analgesia: A retrospective MRI‐based study 下载免费PDF全文
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