全文获取类型
| 收费全文 | 2642284篇 |
| 免费 | 189057篇 |
| 国内免费 | 9295篇 |
专业分类
| 耳鼻咽喉 | 35042篇 |
| 儿科学 | 86185篇 |
| 妇产科学 | 73468篇 |
| 基础医学 | 370550篇 |
| 口腔科学 | 70672篇 |
| 临床医学 | 240558篇 |
| 内科学 | 525610篇 |
| 皮肤病学 | 63477篇 |
| 神经病学 | 216790篇 |
| 特种医学 | 102085篇 |
| 外国民族医学 | 742篇 |
| 外科学 | 393467篇 |
| 综合类 | 54394篇 |
| 现状与发展 | 12篇 |
| 一般理论 | 979篇 |
| 预防医学 | 199218篇 |
| 眼科学 | 57857篇 |
| 药学 | 192712篇 |
| 29篇 | |
| 中国医学 | 6958篇 |
| 肿瘤学 | 149831篇 |
出版年
| 2021年 | 21993篇 |
| 2019年 | 22075篇 |
| 2018年 | 31079篇 |
| 2017年 | 23966篇 |
| 2016年 | 27640篇 |
| 2015年 | 31644篇 |
| 2014年 | 43099篇 |
| 2013年 | 63548篇 |
| 2012年 | 84586篇 |
| 2011年 | 88777篇 |
| 2010年 | 53728篇 |
| 2009年 | 51515篇 |
| 2008年 | 82224篇 |
| 2007年 | 86996篇 |
| 2006年 | 88607篇 |
| 2005年 | 84518篇 |
| 2004年 | 81277篇 |
| 2003年 | 78462篇 |
| 2002年 | 75441篇 |
| 2001年 | 129657篇 |
| 2000年 | 132337篇 |
| 1999年 | 111348篇 |
| 1998年 | 31702篇 |
| 1997年 | 28293篇 |
| 1996年 | 28549篇 |
| 1995年 | 27672篇 |
| 1994年 | 25341篇 |
| 1993年 | 23603篇 |
| 1992年 | 85558篇 |
| 1991年 | 81881篇 |
| 1990年 | 79093篇 |
| 1989年 | 76354篇 |
| 1988年 | 69712篇 |
| 1987年 | 68243篇 |
| 1986年 | 63752篇 |
| 1985年 | 60694篇 |
| 1984年 | 45084篇 |
| 1983年 | 38061篇 |
| 1982年 | 22540篇 |
| 1981年 | 20060篇 |
| 1979年 | 39086篇 |
| 1978年 | 27552篇 |
| 1977年 | 23320篇 |
| 1976年 | 21562篇 |
| 1975年 | 22892篇 |
| 1974年 | 26852篇 |
| 1973年 | 25437篇 |
| 1972年 | 23816篇 |
| 1971年 | 22003篇 |
| 1970年 | 20221篇 |
排序方式： 共有10000条查询结果，搜索用时 22 毫秒
11.
12.
13.
M. Iachina P.M. Ljungdalh R.G. Sørensen L. Kaerlev J. Blaakær O. Trosko N. Qvist B.M. Nørgård 《Clinical oncology (Royal College of Radiologists (Great Britain))》2019,31(2):115-123
Aims
To examine the influence of pre-existing psychiatric disorder on the choice of treatment in patients with gynaecological cancer.Materials and methods
The analyses were based on all patients who underwent surgical treatment for endometrial, ovarian or cervical cancer who were registered in the Danish Gynecological Cancer Database in the years 2007–2014 (3059 patients with ovarian cancer, 5100 patients with endometrial cancer and 1150 with cervical cancer). Logistic regression model and Cox regression model, adjusted for relevant confounders, were used to estimate the effect of pre-existing psychiatric disorder on the course of cancer treatment. Our outcomes were (i) presurgical oncological treatment, (ii) macroradical surgery for patients with ovarian cancer, (iii) radiation/chemotherapy within 30 days and 100 days after surgery and (iv) time from surgery to first oncological treatment.Results
In the group of patients with ovarian cancer, more patients with a psychiatric disorder received macroradical surgery versus patients without a psychiatric disorder, corresponding to an adjusted odds ratio of 1.24 (95% confidence interval 0.62–2.41) and the chance for having oncological treatment within 100 days was odds ratio = 1.26 (95% confidence interval 0.77–2.10). As for patients with endometrial cancer, all outcome estimates were close to unity. The adjusted odds ratio for oncological treatment within 30 days after surgery in patients with cervical cancer with a history of psychiatric disorder was 0.20 (95% confidence interval 0.03–1.54).Conclusions
We did not find any significant differences in the treatment of ovarian and endometrial cancer in patients with pre-existing psychiatric diagnoses. When it comes to oncological treatment, we suggest that increased attention should be paid to patients with cervical cancer having a pre-existing psychiatric diagnosis. 相似文献14.
Background
Total knee arthroplasty is a treatment option for debilitating arthritis. In the postoperative period, patients experience moderate to severe pain affecting the rehabilitation, hospital stay, and patient satisfaction. This study aims at utilizing current best evidence to determine whether adductor canal block (ACB) or periarticular injection (PAI) is a better modality for managing short-term postoperative pain and opioid consumption.Methods
Embase, MEDLINE, HealthStar, Emcare, and PubMed were searched for randomized controlled trials from 1946 to August 2018, for literature addressing the comparison of ACB and PAI for pain management in the setting of total knee arthroplasty. A systematic review and meta-analysis were performed.Results
Six studies were included in our meta-analysis. When examining the combined visual analog scale (VAS) pain values for each group, analysis demonstrated greater reduction in scores for the PAI group, and the difference was statistically significant (P = .001). When comparing the VAS scores of subgroups analyzed at specific periods in time, there was a trend toward lower VAS scores in subgroups analyzed at 24 hours and 48 hours postoperatively (at rest and at movement) in the PAI group. Overall opioid consumption was lower in the PAI group, with demonstrated statistical significance (P = .03). When comparing the postoperative subgroups, there was a trend toward decreased opioid use in the PAI group, with 13.25% less opioid use at 48 hours and 9.5% less opioid use at 24 hours.Conclusion
PAI could significantly improve postoperative pain and opioid consumption when compared with ACB. Additional, high-quality studies are required to further address this topic. 相似文献15.
16.
17.
18.
Fur-Hsing Wen Jen-Shi Chen Wen-Chi Chou Wen-Cheng Chang Wen Chi Shen Chia-Hsun Hsieh Siew Tzuh Tang 《Journal of pain and symptom management》2019,57(1):64-72
Context
Family caregivers constitute a critical component of the end-of-life care system with considerable cost to themselves. However, the joint association of terminally ill cancer patients' symptom distress and functional impairment with caregivers' subjective caregiving burden, quality of life (QOL), and depressive symptoms remains unknown.Objectives/Methods
We used multivariate hierarchical linear modeling to simultaneously evaluate associations between five distinct patterns of conjoint symptom distress and functional impairment (symptom-functional states) and subjective caregiving burden, QOL, and depressive symptoms in a convenience sample of 215 family caregiver–patient dyads. Data were collected every 2 to 4 weeks over patients' last 6 months.Results
Caregivers of patients in the worst symptom-functional states (States 3–5) reported worse subjective caregiving burden and depressive symptoms than those in the best two states, but the three outcomes did not differ between caregivers of patients in State 3 and States 4–5. Caregivers of patients in State 5 endured worse subjective caregiving burden and QOL than those in State 4. Caregivers of patients in State 4 suffered worse subjective caregiving burden and depressive symptoms but comparable QOL to those in State 2.Conclusion
Patients' five distinct, conjoint symptom-functional states were significantly and differentially associated with their caregivers' worse subjective caregiving burden, QOL, and depressive symptoms while caring for patients over their last 6 months. 相似文献19.
20.
Daniel J. Snyder Thomas R. Kroshus Aakash Keswani Evan B. Garden Karl M. Koenig Kevin J. Bozic David S. Jevsevar Jashvant Poeran Calin S. Moucha 《The Journal of arthroplasty》2019,34(4):613-618