中西医结合治疗急性胰腺炎疗效观察

目的:观察中西医结合治疗急性胰腺炎的疗效。方法:西药组23例用西药治疗,中西医结合组19例在用西药治疗的基础上加用柴芍承气汤及丹参注射液治疗。结果:中西医结合组疗效明显优于西药组(P<0.05)。结论:中西医结合治疗急性胰腺炎可明显改善急性期症状,减少并发症,改善预后。     

抗凝血酶Ⅲ测定在评价肝脏功能中的应用

测定110例肝病的抗凝血酶Ⅲ(AT-Ⅲ)活性,62例低于正常(56.4％),均值为60.1±38.2％。50例正常对照为100.0±26.7％。重症肝炎、慢性活动性肝炎及失代偿期肝硬化活性显著下降,均值分别为12.9±13.0％、51.0±34.6％、43.3±29.6％.AT-Ⅲ活性在评价肝脏功能方面较凝血酶原时间敏感,具有一定的实用意义。     

Ignoring Distant Genealogic Loops Leads to False-positives in Homozygosity Mapping

Distant consanguineous loops are often unknown or ignored during homozygosity mapping analysis. This may potentially lead to an increased rate of false-positive linkage results. We show that failure to take into account the distant loops may seriously underestimate the degree of consanguinity, especially for people from genetically isolated populations; in 6 Alzheimer's disease (AD) patients the distant loops accounted for 57.7 % of inbreeding on average. Theoretical evaluation showed that ignoring distant loops, which account for 18-75% of inbreeding, inflates the frequency of false positive conclusions substantially in 2-point linkage analysis, up to several hundred times. In multipoint linkage analysis of the 6 AD patients a chromosome-wide "empirical" significance of 5% corresponded to a true false positive rate of 11.1%. We show that converting multiple loops to a hypothetical loop capturing all inbreeding may be a convenient solution to avoid false positive results. When extended genealogic data are not available a hypothetical loop may still be constructed based on genomic data.     

关于老年人植入心脏起搏器术后疗养康复的体会

目的避免或减少老年人植入心脏起搏器术后疗养康复过程中起搏器故障和相关疾病的发生。积极治疗基础疾病,改变其不良症状,并通过心理治疗改善不良心理情绪,使其增强自信,提高生活质量。方法入院后,详细了解安置起搏器的时间、类型及工作情况,全面掌握其身体状况和心理特点,为其制定合理的疗养计划。结果疗养期结束后,疗养员无一例出现起搏器故障和发生相关疾病;基础疾病及不良症状得到进一步控制,心理不良情绪得到进一步控制,基本达到了疗养的目的。结论疗养院医务人员应全面了解起搏器的类型及特性;掌握安置起搏器的适应症和容易出现的病症;掌握此类疗养员的身体情况和心理特点,制定合理的疗养计划并按计划认真予以实施,是保证老年人植入心脏起搏器疗养员能够顺利完成疗养生活的有效措施。     

Toluene vapor exposure and urinary excretion of hippuric acid among workers in China.

A factory survey was conducted in three provinces in China from 1985 to 1989. The time-weighted average toluene concentrations in breathing zone air were monitored by diffusive sampling, whereas hippuric acid (HA) concentrations in shift-end urine samples were measured by high performance liquid chromatography (HPLC). Exposed workers (456 men and women) were those for whom toluene (up to 548 ppm toluene) accounted for greater than or equal to 90% of total exposure (by vapor concentration in ppm), whereas 517 nonexposed controls were recruited from the same factories or from factories of the same region. There was a linear correlation between the intensity of toluene exposure and HA concentration in the shift-end urine. Comparison of the results with findings in the literature shows that the toluene-induced increase in urinary HA concentration among workers in China is significantly smaller than the published values, whereas HA concentrations in urine samples from nonexposed controls are comparable to the levels previously reported.     

Uncomplicated amebic liver abscess: prospective evaluation of percutaneous therapeutic aspiration.

The performance of therapeutic aspiration in the treatment of amebic liver abscess, advocated and practiced in many centers, is controversial. Previously, this practice has been evaluated in retrospective analyses. To test the potential benefit of therapeutic aspiration, the authors undertook a prospective randomized trial in 57 patients admitted for suspected amebic liver abscess during a 15-month period. Sixteen patients were excluded from the trial. The remaining 41 patients were randomly included in one of two study groups to receive amebicidal therapy alone or amebicidal therapy coupled with image-guided percutaneous therapeutic aspiration. All patients in the trial recovered. No statistically significant benefit was demonstrated in the aspiration group for the two objective parameters evaluated: length of hospitalization and duration of time to becoming afebrile. Subjective improvement in symptoms after aspiration was greater in the aspiration group at a marginally statistically significant level. These data do not support the adjunctive performance of percutaneous therapeutic aspiration in the treatment of uncomplicated amebic liver abscess. Amebicidals alone were equally efficacious in treating the group studied.     

二期后房型人工晶体植入术

本文报道对16只(16例)后囊膜完整的无晶体眼进行后房型人工晶体二期植入术的结果.术前的平均未矫正视力为0.06,术后半年,平均未矫正视力为0.53未矫正视力≥0.5的达62.50%,矫正视力≥0.5的占93.37%,≥1.0的占81.25%.术前角膜中央内皮细胞密度平均2646个/mm~2,术后半年为1824个/mm~2,除一例外,其余可恢复立体视.无一例发生持续性角膜水肿和葡萄膜炎等严重并发症.结果表明,只要掌握适应症和手术技术,在后囊膜完整的无晶体眼作二期后房型人工晶体植入是安全有效的方法.本文对手术的适应症、手术方式和技术进行了探讨.     

甲状腺肿瘤X线造影与超声检查对比分析

本文报告了经手术病理证实的53例甲状腺肿瘤,均作了甲状腺造影和B超检查.通过比较分析,我们认为造影对确定肿瘤的良、恶性以及延伸到胸骨后的异位甲状腺肿瘤有其优越性,是一项有效的检查方法;超声则能准确地判断肿瘤的囊、实性,适合碘过敏患者的检查.两种检查各有特点,配合使用有利于对甲状腺肿瘤的诊断和治疗.     

氨基酸、有机酸、碱基核苷类化合物的双向色谱多相同步分析

30余种氨基酸、40余种非挥发性有机酸和20余种碱基核苷类化合物在一块薄层板上完成多相同步色谱分析；用紫外灯-吖啶试剂-镉茚三酮试剂实行组合显色定位分析。改善了尿液中非挥发性有机酸的溶剂萃取法，尿中三类化合物提取物的同步多相色谱分离效果良好。