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991.
992.
Ferreira Junior Adalberto Garavelo João Julio Altimari Leandro Ricardo Gabardo Juliano Moro Freitas Luis Alberto Garcia Buzzachera Cosme Franklim Del Conti Esteves João Victor da Silva Sérgio Gregório de Moraes Solange Marta Franzói 《Sport Sciences for Health》2020,16(3):459-464
Sport Sciences for Health - Obesity is related to negative changes in insulin resistance and liver enzymes and is associated with the risk factor for the development of type II diabetes mellitus... 相似文献
993.
Leandro Cardoso BARCHI Marcus Fernando Kodama Pertille RAMOS Osmar Kenji YAGI Donato Roberto MUCERINO Claudio Jos Caldas BRESCIANI Ulysses RIBEIRO JÚNIOR Nelson Adami ANDREOLLO Paulo Pimentel ASSUMPO Antnio Carlos WESTON Ramiro COLLEONI NETO Bruno ZILBERSTEIN Consensus members 《Brazilian archives of digestive surgery》2020,33(3)
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João J. Garavelo Leandro R. Altimari Juliano M. Gabardo Adalberto Ferreira-Junior Luis A.G. Freitas Cosme F. Buzzachera João V.D.C. Esteves Sergio G. da Silva Solange M.F. de Moraes 《Obesity research & clinical practice》2019,13(2):211-213
To evaluate the effects of 12-weeks of walk training with self-selected intensity on lipid profile and anthropometric variables in women with obesity. Forty-eight women volunteers with obesity were randomly assigned into two training groups: self-selected walking group (SSWG; n = 25) and control group (CG; n = 23). There was improvement in biochemical markers only in the SSWG post-intervention (p < 0.05), however no changes were verified in anthropometric variables (p > 0.05). This study demonstrates that walking at self-selected intensity improved the lipid profile in women with obesity. 相似文献
997.
Athanase Billis Maisa M.Q Quintal Leandro L.L Freitas Larissa B. E. Costa Ubirajara Ferreira 《International braz j urol : official journal of the Brazilian Society of Urology》2015,41(2):367-372
Objective
The aim of active surveillance of early prostate cancer is to individualize therapy by selecting for curative treatment only patients with significant cancer. Epstein’s criteria for prediction of clinically insignificant cancer in surgical specimens are widely used. Epstein’s criterion “no single core with >50% cancer” has no correspondence in linear extent. The aim of this study is to find a possible correspondence.Materials and Methods
From a total of 401 consecutive patients submitted to radical prostatectomy, 17 (4.2%) met criteria for insignificant cancer in the surgical specimen. The clinicopathologic findings in the correspondent biopsies were compared with Epstein’s criteria for insignificant cancer. Cancer in a single core was evaluated in percentage as well as linear extent in mm.Results
Comparing the clinicopathologic findings with Epstein’s criteria predictive of insignificant cancer, there was 100% concordance for clinical stage T1c, no Gleason pattern 4 or 5, ≤2 cores with cancer, and no single core with >50% cancer. However, only 25% had density ≤0.15. The mean, median and range of the maximum length of cancer in a single core in mm were 1.19, 1, and 0.5-2.5, respectively. Additionally, the mean, median, and range of length of cancer in all cores in mm were 1.47, 1.5, and 0.5-3, respectively.Conclusion
To pathologists that use Epstein’s criteria predictive of insignificant cancer and measure linear extent in mm, our study favors that “no single core with >50% cancer” may correspond to >2.5 mm in linear extent. 相似文献998.
999.
Braz JR do Nascimento P Paiva Filho O Braz LG Vane LA Vianna PT Rodrigues GR 《Anesthesia and analgesia》2004,99(2):536-46, table of contents
The smaller volemic state from hypertonic (7.5%) saline (HS) solution administration in hemorrhagic shock can determine lesser systemic oxygen delivery and tissue oxygenation than conventional plasma expanders. In a model of hemorrhagic shock in dogs, we studied the systemic and gastrointestinal oxygenation effects of HS and hyperoncotic (6%) dextran-70 in combination with HS (HSD) solutions in comparison with lactated Ringer's (LR) and (6%) hydroxyethyl starch (HES) solutions. Forty-eight mongrel dogs were anesthetized, mechanically ventilated, and subjected to splenectomy. A gastric air tonometer was placed in the stomach for intramucosal gastric CO(2) (Pgco(2)) determination and for the calculation of intramucosal pH (pHi): The dogs were hemorrhaged (42% of blood volume) to hold mean arterial blood pressure at 40-50 mm Hg over 30 min and were then resuscitated with LR (n = 12) in a 3:1 relation to removed blood volume; HS (n = 12), 6 mL/kg; HSD (n = 12), 6 mL/kg; and HES (mean molecular weight, 200 kDa; degree of substitution, 0.5) (n = 12) in a 1:1 relation to the removed blood volume. Hemodynamic, systemic, and gastric oxygenation variables were measured at baseline, after 30 min of hemorrhage, and 5, 60, and 120 min after intravascular fluid resuscitation. After fluid resuscitation, HS showed significantly lower arterial pH and mixed venous Po(2) and higher systemic oxygen uptake index and systemic oxygenation extraction than LR and HES (P < 0.05), whereas HSD showed significantly lower arterial pH than LR and HES (P < 0.05). Only HS and HSD did not return arterial pH and pHi to control levels (P < 0.05). In conclusion, all solutions improved systemic and gastrointestinal oxygenation after hemorrhagic shock in dogs. However, the HS solution showed the worst response in comparison to LR and HES solutions in relation to systemic oxygenation, whereas HSD showed intermediate values. HS and HSD solutions did not return regional oxygenation to control values. 相似文献
1000.
Amparo Verdeguer Jose Gabriel Ruiz Josep Ferris Carlos Esquembre Maria Jesus Tasso Jose Maria Fernandez Felix Prieto Victoria Castel 《Pediatric blood & cancer》1992,20(1):48-52
Some cases of conversion from acute lymphoblastic leukemia (ALL) to acute nonlymphoblastic leukemia (ANLL) at relapse have been reported recently. We report three cases initially diagnosed as having ALL and showing morphological, cytochemical, and immunophenotypic features of ANLL at relapse (lineage switch). Conversion was observed among 14 patients who developed bone marrow relapse while undergoing intensive treatment with our ALL protocol, which includes teniposide, and that had been administered to 62 patients. The three cases converted at first relapse, with a mean time of 20 months (13–29 months). Clinical and immunologic characteristics of T-cell leukemia were present in one patient. Changes documented in cytogenetic studies are discussed. The underlying mechanisms for the lineage switch remain unclear as does its relation with mixed lineage leukemias, but we believe that drugs employed in our therapy protocol could have had an influence on this conversion. 相似文献