全文获取类型
收费全文 | 7254篇 |
免费 | 493篇 |
国内免费 | 289篇 |
专业分类
耳鼻咽喉 | 52篇 |
儿科学 | 151篇 |
妇产科学 | 126篇 |
基础医学 | 1058篇 |
口腔科学 | 147篇 |
临床医学 | 736篇 |
内科学 | 1536篇 |
皮肤病学 | 108篇 |
神经病学 | 558篇 |
特种医学 | 171篇 |
外国民族医学 | 7篇 |
外科学 | 603篇 |
综合类 | 608篇 |
现状与发展 | 1篇 |
一般理论 | 1篇 |
预防医学 | 349篇 |
眼科学 | 288篇 |
药学 | 682篇 |
1篇 | |
中国医学 | 189篇 |
肿瘤学 | 664篇 |
出版年
2024年 | 9篇 |
2023年 | 101篇 |
2022年 | 179篇 |
2021年 | 303篇 |
2020年 | 176篇 |
2019年 | 195篇 |
2018年 | 197篇 |
2017年 | 180篇 |
2016年 | 194篇 |
2015年 | 258篇 |
2014年 | 308篇 |
2013年 | 327篇 |
2012年 | 508篇 |
2011年 | 570篇 |
2010年 | 306篇 |
2009年 | 264篇 |
2008年 | 440篇 |
2007年 | 461篇 |
2006年 | 420篇 |
2005年 | 480篇 |
2004年 | 372篇 |
2003年 | 375篇 |
2002年 | 325篇 |
2001年 | 97篇 |
2000年 | 109篇 |
1999年 | 123篇 |
1998年 | 102篇 |
1997年 | 100篇 |
1996年 | 72篇 |
1995年 | 62篇 |
1994年 | 57篇 |
1993年 | 40篇 |
1992年 | 35篇 |
1991年 | 47篇 |
1990年 | 27篇 |
1989年 | 33篇 |
1988年 | 17篇 |
1987年 | 21篇 |
1986年 | 21篇 |
1985年 | 9篇 |
1984年 | 15篇 |
1983年 | 13篇 |
1982年 | 11篇 |
1981年 | 15篇 |
1980年 | 11篇 |
1979年 | 14篇 |
1978年 | 8篇 |
1976年 | 4篇 |
1974年 | 4篇 |
1971年 | 4篇 |
排序方式: 共有8036条查询结果,搜索用时 15 毫秒
91.
Mild inflammation persists in the glenohumeral joint of patients with recurrent shoulder dislocation
92.
93.
目的:探讨剪切波弹性成像(shear wave elastography,SWE)与细针穿刺洗脱液甲状腺球蛋白(fine-needle aspiration washout thyroglobulin,FNA-Tg)对甲状腺乳头状癌侧颈部淋巴结转移的诊断价值。方法:回顾性分析159例经病理证实为甲状腺乳头状癌(papillary thyroid carcinoma,PTC)的患者资料,对颈部211枚可疑淋巴结进行常规超声、SWE参数平均值(Emean)、FNA-Tg检查,以术后病理结果为金标准,比较各检测方法的诊断效能。结果:(1)SWE Emean转移组[(50.96±27.66) kPa]高于非转移组[(32.20±17.34) kPa],差异有统计学意义(t=8.761,P<0.01)。受试者工作特征(receiver operating characteristic,ROC)曲线分析表明,SWE Emean最佳诊断阈值为40.42 kPa时对PTC颈部淋巴结转移预测价值较高,曲线下面积(area under... 相似文献
94.
目的 :探讨人乳头瘤病毒 (HPV) 1 6在舌癌细胞中存在的形式 ,以分析该病毒在舌癌发生中的意义。方法 :采用 Southern blot杂交技术对 2 0例新鲜舌癌组织进行 HPV1 6型基因组 DNA存在状态分析。结果 :2 0例舌癌中有 5例检测出 HPV1 6病毒基因序列 ,该病毒在舌癌中主要以游离形式存在于细胞基因组之外。结论 :HPV1 6在舌癌发生中的作用不是通过病毒基因与细胞基因组整合产生的。推测 HPV某些基因产物与靶细胞某些基因相互作用可能是该病毒致病的途径 相似文献
95.
为观察苏林酸对结肠腺癌HT-29细胞有无促凋亡作用,采用流式细胞仪检测、DNA电泳和透射电镜观察苏林酸对HT-29细胞的促凋亡作用。结果:流式细胞式、DNA电泳和透射电镜观察均显示苏林酸可诱导HT-29细胞凋亡,且具有时间和剂量依赖性。用0.3mmol/L、0.6mmol/L和1.2mmol/L苏林酸处理48小时,凋亡细胞分别占5.8%、7.6%和11.7%,处理72小时则分别升为12.5%、15 相似文献
96.
Patton Daniella Ghosh Adarsh Farkas Amy Sotardi Susan Francavilla Michael Venkatakrishna Shyam Bose Saurav Ouyang Minhui Huang Hao Davidson Richard Sze Raymond Nguyen Jie 《Journal of digital imaging》2023,36(4):1419-1430
Journal of Digital Imaging - Measurement of angles on foot radiographs is an important step in the evaluation of malalignment. The objective is to develop a CNN model to measure angles on... 相似文献
97.
目的 探究Chevron截骨术截骨远端外侧位移距离对外翻足关节接触特征的影响,为临床上选择合适的位移距离提供参考依据。方法 测量踝关节中立位状态下正常足、外翻足及外翻足Chevron截骨术截骨远端分别向外侧位移2.0、4.0、6.0 mm后前足、中足和后足各关节接触力、峰值压强和接触面积,并对结果进行分析。结果 与正常足相比,外翻足第1跖楔关节(t=-3.33, P=0.02)、跟骰关节(t=-2.74, P=0.03)和距下关节(后关节面)(t=-2.89, P=0.03)的接触力显著增高;外翻足距舟关节(t=-2.73, P=0.03)与跟骰关节(t=-2.74, P=0.03)的峰值压强显著增高;行Chevron截骨术后,随着截骨远端向外侧位移距离的增加,外翻足第1跖楔关节和跟骰关节的接触力逐渐减小;外翻足距舟关节和跟骰关节的峰值压强逐渐减小。结论 中度外翻足行Chevron截骨术后,当第1跖骨截骨远端向外侧位移6 mm时能有效恢复部分关节间力的分布,且能缓解部分关节局部应力集中现象。 相似文献
98.
Tomomi Yamaguchi Shujiro Hayashi Daisuke Hayashi Takeshi Matsuyama Norimichi Koitabashi Kenichi Ogiwara Masaaki Noda Chiai Nakada Shinya Fujiki Akira Furutachi Yasuhiko Tanabe Michiko Yamanaka Aki Ishikawa Miyako Mizukami Asako Mizuguchi Kazumitsu Sugiura Makoto Sumi Hirokuni Yamazawa Atsushi Izawa Yuko Wada Tomomi Fujikawa Yuri Takiguchi Keiko Wakui Kyoko Takano Shin-Ya Nishio Tomoki Kosho 《American journal of medical genetics. Part A》2023,191(1):37-51
Vascular Ehlers–Danlos syndrome (vEDS) is a hereditary connective tissue disorder (HCTD) characterized by arterial dissection/aneurysm/rupture, sigmoid colon rupture, or uterine rupture. Diagnosis is confirmed by detecting heterozygous variants in COL3A1. This is the largest Asian case series and the first to apply an amplification-based next-generation sequencing through custom panels of causative genes for HCTDs, including a specific method of evaluating copy number variations. Among 429 patients with suspected HCTDs analyzed, 101 were suspected to have vEDS, and 33 of them (32.4%) were found to have COL3A1 variants. Two patients with a clinical diagnosis of Loeys–Dietz syndrome and/or familial thoracic aortic aneurysm and dissection were also found to have COL3A1 variants. Twenty cases (57.1%) had missense variants leading to glycine (Gly) substitutions in the triple helical domain, one (2.9%) had a missense variant leading to non-Gly substitution in this domain, eight (22.9%) had splice site alterations, three (8.6%) had nonsense variants, two (5.7%) had in-frame deletions, and one (2.9%) had a multi-exon deletion, including two deceased patients analyzed with formalin-fixed and paraffin-embedded samples. This is a clinically useful system to detect a wide spectrum of variants from various types of samples. 相似文献
99.
明代《伤寒论》研究对后世的影响 总被引:1,自引:1,他引:0
Ouyang B 《Zhonghua yi shi za zhi (Beijing, China : 1980)》1995,25(2):92-94
系统研究了明代《伤寒论》文献,指出明代《伤寒论》研究对后世的影响,主要表现在温病学说直接受其催化而趋于成熟,明刻本《伤寒论》为后世提供了研究依据,重编整理导致了后世编次方法之多样,学术论争深化了后世的《伤寒论》研究。认为明代是《伤寒论》研究史上承前启后的重要时期,明代的《伤寒论》研究影响并规定了清代乃至近代的《伤寒论》研究模式和水平。 相似文献
100.
Timothy J. Buckley Jed M. Waldman Ramana Dhara Arthur Greenberg Zheng Ouyang Paul J. Lioy 《International archives of occupational and environmental health》1995,67(4):257-266
Urinary banzo[a]pyrene (BaP) metabolite levels were compared to human environmental exposure to BaP through inhalation and dietary ingestion to assess the predictive validity of the exposure biomarker. These measurements were made for 14 adult volunteers over 14 consecutive days, once during summer/fall, again during winter periods. Based on personal air monitoring, median potential inhalation doses of 11.0 and 2.3 ng/day were estimated for the winter and summer/fall studies, respectively. A median potential ingested dose of 176 ng/day, estimated from duplicate plate sampling, exceeded inhalation by 6-and 122-fold for the winter and summer/fall studies, respectively. Total urinary BaP metabolites were measured using a published reverse metabolism (BaP) method of analysis. Median rates of urinary BaP metabolite elimination for the winter and summer/fall studies were 121 and 129 ng/day, respectively. The changes in inhaled and ingested potential doses were regressed on the change in urinary metabolite elimination from week 1 to week 2 to test the predictive validity of the biomarker measurement. The regression was statistically significant (r = 0.620, p = 0.015, n = 25) when body weight was included and two extreme values were removed. Consistent with the exposure measurements showing diet as the dominant route of exposure, most of the variation in urinary metabolite elimination was explained by the ingested dose. It is concluded that the measurement of urinary BaP by reverse metabolism is qualitative and of marginal predictive validity as an exposure biomarker due to the method's low recoveries and the large unexplained variance. 相似文献