Crystallodiagnostics of some animals' helmintosis

ObjectiveTo investigate the teziocrystalloscopic features of urine which were collected from both healthy rodents and those with parasitosis.MethodsPhysical-chemical characteristics of urine samples that were collected from 15 mice and 20 rats were estimated by their ability to crystallize. Crystallization test results were interpreted with integrated identity table which includes 5 main classes of the crystalline and amorphous formations. Additional quantitative and semiquantitative evaluation indicators were also used.ResultsPresence of Trichinella spiralis in animal organism transformed results of the biofluid free crystallogenesis. The main components of rats' urine facia were single-crystalline rectangles which were made of cholesterol and its derivatives. The biofluid microsamples of healthy rats and rats with echinococcosis had both common and difference.ConclusionsUrine teziocrystalloscopic analysis is an informative method for diagnosis of helminthiasis in animals.     

Present status of agonistic and antagonistic analogs of LH-RH in the treatment of advanced prostate cancer

The methods for treatment of advanced prostate cancer, based on the agonistic analogs of LH-RH were reviewed. New therapeutic approaches utilizing antagonistic analogs of LH-RH such as SB-75 (Cetrorelix) have been described. Analogs of LH-RH chemically linked to various cytotoxic radicals are also being developed. Combinations of LH-RH agonists or antagonists with superactive somatostatin analogues such as Octastatin (RC-160) or with bombesin/GRP antagonists are being investigated in order to delay or prevent the relapse and improve the therapy for prostate cancer.     

Paraneoplastic vasculitis associated with multiple myeloma

The association between vasculitis and cancer has been widely reviewed in recent decades. The existence of malignancies in patients with vasculitis has been estimated at about 4.5-8%, haematological neoplasms being the most frequently observed. The haematological malignancies most frequently described are lymphoproliferative diseases such as hairy cell leukaemia and lymphomas. On the contrary, the incidence of paraneoplastic vasculitis in patients with myeloma is low; up to now, we have found nine cases reported on this subject. We report the case of a 73-year-old woman who in 1 year showed three outbreaks of acutely painful, purpuric and ulceronecrotic lesions, localized on the lower extremities. Histopathological study demonstrated thrombosis in the arterioles and leucocytoclastic vasculitis. Complementary tests revealed the presence of multiple myeloma.     

Lung torsion: case report and literature review

A 65-year-old woman with endobronchial carcinoma had torsion of the left upper lobe. A posteroanterior chest radiograph showed apparent atelectasis in the left upper lobe, but the lateral view disclosed an inappropriate posterior displacement of the collapsed lobe. The vasculature of the affected area showed an unusual curvature. Review of 21 examples of lung torsion disclosed no characteristic age, sex, or affected lobe. The most common associations were with previous surgery (n = 10) or a history of trauma (n = 5). The most common radiographic findings are opacification of the affected lobe (n = 12), an abnormal vascular pattern (n = 6), and an abnormal location for the atelectatic lung (n = 5). Affected lobes often show hemorrhagic infarction or necrosis.     

Apical opacity: a normal finding on posteroanterior chest radiographs

Of 423 posteroanterior chest radiographs in patients aged 21-66 years, 12.8% showed a homogeneous oval opacity with unsharp margins at the right apex and 16.8% at the left apex. Anatomy of the vessel, observations in patients with pneumothorax or atherosclerotic calcification, and fluoroscopic and computed tomographic evidence lead to the conclusion that the apical opacity is produced by the subclavian artery.