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71.
We report the unusual association of facial palsy and severe hypertension in an infant with coarctation of the aorta. The facial palsy resolved before the hypertension was cured. 相似文献
72.
Objective : To describe the presentation and investigation of an unusual form of congenital dorsal midline thoracic mass.
Results : An infant born by emergency Caesarean section at 34 weeks gestation was found to have a large dorsal midline thoracic mass. The infant had normal neurological function in all limbs. Radiological investigation showed no abnormality in the vertebrae. Ultrasonographic investigation suggested the mass to consist of subcutaneous oedema. The mass resolved completely within the first 2 weeks.
Conclusions : The lesion observed in this infant represents a very unusual location for a benign condition caused by cervical pressure on the presenting fetal part. The use of ultrasonography enabled rapid exclusion of the more common, potentially serious, causes of a congenital midline dorsal thoracic mass. 相似文献
Results : An infant born by emergency Caesarean section at 34 weeks gestation was found to have a large dorsal midline thoracic mass. The infant had normal neurological function in all limbs. Radiological investigation showed no abnormality in the vertebrae. Ultrasonographic investigation suggested the mass to consist of subcutaneous oedema. The mass resolved completely within the first 2 weeks.
Conclusions : The lesion observed in this infant represents a very unusual location for a benign condition caused by cervical pressure on the presenting fetal part. The use of ultrasonography enabled rapid exclusion of the more common, potentially serious, causes of a congenital midline dorsal thoracic mass. 相似文献
73.
Whitehouse PA Mercer SJ Knight LA Di Nicolantonio F O'Callaghan A Cree IA;Portsmouth Upper GI Colorectal Cancer Multidisciplinary Teams 《British journal of cancer》2003,89(12):2299-2304
Advanced or metastatic disease is common in both oesophagogastric and colorectal cancers, with poor 5-year survival despite palliative chemotherapy. We have investigated the sensitivity of gastrointestinal tumours to gemcitabine in combination with mitomycin C (GeM), using a modified ex vivo ATP-based tumour chemosensitivity assay (ATP-TCA). Tumour material from 41 colorectal and 22 oesophagogastric cancers were assessed. The GeM combination showed variable but definite activity in most of the samples tested. The results show that GeM achieves >95% inhibition at concentrations within the range achievable clinically in 60% of colorectal tumours (21 out of 35) and 38% of oesophagogastric tumours (five out of 13) tested. We did not identify any significant difference in sensitivity using concurrent or sequential exposure of tumour-derived cells to these two drugs. The results from this study suggest that GeM may be a useful combination in the treatment of advanced gastrointestinal malignancy. 相似文献
74.
We review evidence suggesting that the brain of maternally behaving rats is altered as a result of the behavior of the animal towards her pups. Morphological changes seen in the supraoptic nucleus, which contains oxytocinergic neurons important for lactation, are observed not only in parturient, lactating animals but also in virgin animals induced by the presence of rat pups to behave maternally. The supraoptic nuclei of lactating and maternally behaving virgin animals have a higher incidence of dendritic bundling relative to non-maternal virgin animals. Also, stimulation of the lateral olfactory tract in in vitro brain slices elevates electrotonic coupling among supraoptic neurons only in maternally behaving animals and not in male or non-maternal virgins. In general the evidence presented supports the idea that maternal behavior in lactating and non-lactating animals, can have profound effects on the morphology and physiological functioning of oxytocinergic neurons in the hypothalamus. 相似文献
75.
Variants of Brugada Syndrome and Early Repolarization Syndrome: An Expanded Concept of J‐Wave Syndrome 下载免费PDF全文
SUNG‐HWAN KIM M.D. GI‐BYOUNG NAM M.D. SUNG‐CHEOL YUN Ph.D. HYUNG OH CHOI M.D. KEE‐JOON CHOI M.D. BOYOUNG JOUNG M.D. HUI‐NAM PAK M.D. MOON‐HYOUNG LEE M.D. SUNG SOON KIM M.D. SEUNG‐JUNG PARK M.D. YOUNG KEUN ON M.D. JUNE SOO KIM M.D. IL‐YOUNG OH M.D. EUE‐KEUN CHOI M.D. SEIL OH M.D. F.H.R.S. YUN‐SHIK CHOI M.D. JONG IL CHOI M.D. SANG WEON PARK M.D. YOUNG‐HOON KIM M.D. YONG‐SEOG OH M.D. MAN YOUNG LEE M.D. HONG EUY LIM M.D. YOUNG‐SOO LEE M.D. YONGKEUN CHO M.D. JUN KIM M.D. KYOUNG‐SUK RHEE M.D. DONG‐IL LEE M.D. DAE KYOUNG CHO M.D. YOU‐HO KIM M.D. 《Pacing and clinical electrophysiology : PACE》2017,40(2):162-174
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目的 建立铜绿假单胞菌(PA)肺部感染大鼠慢性阻塞性肺疾病(COPD)模型,研究Flt3L(Fms-like tyrosine kinase-3 ligand )对其炎症反应的防治作用.方法 将50只健康雄性清洁级Wistar大鼠随机分为对照组(NS组)、PA感染对照组(NPA组)、COPD大鼠组(COPD组)、COPD大鼠PA感染组(CPA组)和COPD大鼠PA感染Flt3L处理组(Flt3L组),每组动物各10只.用烟雾暴露法复制大鼠COPD模型,气管内滴入PA溶液复制肺部PA感染模型.COPD组、CPA组、Flt3L组大鼠分别在第1~60天以烟雾暴露法复制COPD模型,Flt3L组于第61~65天连续给予Flt3L(20g/kg)腹腔注射,每天1次,连续5d,第66天同时建立NPA组、CPA组和Flt3L组模型.24h后计算大鼠死亡率,对支气管肺泡灌洗液(BALF)、肺组织进行细菌学、细胞学、病理学等研究.无菌操作下取出大鼠脏器进行细菌培养、菌落计数及细菌鉴定.结果 Flt3L组大鼠存活率(87.5%)显著高于CPA组(50.0%)(P<0.01),Flt3L组大鼠支气管肺泡灌洗液中淋巴细胞数[(0.41~0.05)×109/L]与CPA组[(0.24~0.04)×109/L]比较显著增加(P<0.01),光镜下观察比较发现Flt3L组大鼠肺组织炎症反应较CPA组明显减轻,脏器细菌培养阳性率CPA组(37.5%)显著高于Flt3L组(12.5%)(P<0.01).结论 Flt3L能够增强COPD大鼠对PA肺部感染的抗病力. 相似文献
80.
Betsie GI van Gaal Lisette Schoonhoven Marlies EJL Hulscher Joke AJ Mintjes George F Borm Raymond TCM Koopmans Theo van Achterberg 《BMC health services research》2009,9(1):58