Dermatologische Veränderungen beim Felty-Syndrom

Ohne ZusammenfassungHerrn Prof. Dr. E. Letterer zum 65. Geburtstag am 30. 6. 1960.     

Haptoglobin- und Coeruloplasmin-Bestimmungen beim experimentellen Lathyrismus der Ratte

Zusammenfassung Bei Ratten wurde experimentell durch -Aminopropionitril Lathyrismus erzeugt. Die beiden Serum-Proteine Haptoglobin und Coeruloplasmin zeigten hinsichtlich ihrer Serum-Spiegelvor undnach der Behandlung keine statistisch signifikanten Unterschiede. Die Peroxydase- und Oxydase-Aktivität des Ratten-Serums wird demnach durch diese Behandlung nicht verändert. Da der Kohlenhydrat-Anteil des Haptoglobins aus der Grundsubstanz stammen soll, ist demnach durch -Aminopropionitril keine Veränderung dieses Anteils festzustellen. Das in der Leber synthetisierte Coeruloplasmin erleidet ebenfalls — zumindest quantitativ — keine Veränderungen.

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Summary Lathyrism was produced in rats by feeding -aminopropionitril. Haptoglobin and Coeruloplasmin serum levels showed no significant difference before and after treatment. Encymatic activity of Haptoglobin and Coeruloplasmin therefore appears not to be changed in lathyric rat. Thus the assumption that the carbohydrate part of Haptoglobin originates from the groundsubstance could not be confirmed by these assays.

     

Zur Kenntnis viscerocutaner Wechselwirkungen mit hoher Bluteosinophilie unter dem Bilde des Löfflerschen Lungeninfiltrates und des Erythema scarlatiniforme des quamativum recidivans

Ohne ZusammenfassungMit 2 TextabbildungenProfessor Dr. H. Th. Schreus zum 65. Geburtstag am 16. 9. 1957.     

Octreotide dependency and headache: a case report

We report on headache induced by a somatostatin octapeptide analog (octreotide) used for the treatment of acromegaly, This "rebound" headache has severe tension-type characteristics and occurs every 6–8 h. It resolves dramatically within minutes with octreotide administration. This is the first report of headache developing under treatment with octreotide.     

Etiology and pathogenesis of Attention-deficit Hyperactivity Disorder (ADHD): significance of prematurity and perinatal hypoxic-haemodynamic encephalopathy

Attention-deficit Hyperactivity Disorder (ADHD), defined as a disorder of awareness with impul-sivity, has lately been characterized as a dysfunction of the striatum (neostriatum = globus pallidus + putamen). This structure is in a unique position for contextual analysis and samples information from almost the entire cortex through its spiny neurons. The etiology is heterogeneous, with genetic as well as lesional factors. Among the latter, pre- and perinatal events are prominent. Advances in the understanding of the role of fetal circulatory insufficiency with loss of autoregulation and systemic hypotension have drawn attention to the vulnerability of watershed regions, including the striatum. Not only circulatory facts are important for this selectivity, however. The anatomical characteristics, with convergent glutaminergic afferent synaptic transmission from almost the entire cortex contribute to the vulnerability in ischemia-induced liberation of glutamate: The striatum becomes the victim of its virtue. Repeated hypoxic-ischemic events are particularly common in prematurity, a fact which seems to explain the high incidence of ADHD in this patient group. The magnitude of the problem is increasing with the increased survival rate among premature infants.     

Innerfamiliäre Übertragung von Trichophyton verrucosum auf ein Neugeborenes Transfer of Trichophyton verrucosum to a Newborn withm a Family

At the age of 4 weeks a suckling developed discoid erythema with scales and a few pustules at the face. Previously, his father having contact with cattle as a farmer had fallen ill from tinea barbae. In both cases Trichophyton verrucosum could be detected by culture. Dermatophytosis in sucklings has recently more often been reported about in the literature. This, however, does not apply to Tr. verrucosum infections.     

PREVALENCE OF MITRAL VALVE PROLAPSE IN HONG KONG CHINESE A CLINICAL AND AUTOPSY STUDY

The prevalence of mitral valve pro.lapse in Chinese was determined by screening 156 heal- thy subjects and by patholobic examination of 86 adult autopsies. Mitral valve prolapse was found in 7.7% in the clinical study and 5.8% in the autopsy study. A slight female preponderance was noted.