全文获取类型
收费全文 | 331038篇 |
免费 | 11178篇 |
国内免费 | 1213篇 |
专业分类
耳鼻咽喉 | 3337篇 |
儿科学 | 9518篇 |
妇产科学 | 6684篇 |
基础医学 | 39952篇 |
口腔科学 | 4846篇 |
临床医学 | 27177篇 |
内科学 | 60594篇 |
皮肤病学 | 4975篇 |
神经病学 | 28104篇 |
特种医学 | 16614篇 |
外科学 | 49770篇 |
综合类 | 4426篇 |
现状与发展 | 5篇 |
一般理论 | 81篇 |
预防医学 | 27376篇 |
眼科学 | 6960篇 |
药学 | 22273篇 |
中国医学 | 2218篇 |
肿瘤学 | 28519篇 |
出版年
2023年 | 986篇 |
2022年 | 2740篇 |
2021年 | 4824篇 |
2020年 | 2467篇 |
2019年 | 3593篇 |
2018年 | 25704篇 |
2017年 | 20102篇 |
2016年 | 23114篇 |
2015年 | 6471篇 |
2014年 | 7652篇 |
2013年 | 9061篇 |
2012年 | 19317篇 |
2011年 | 32618篇 |
2010年 | 25475篇 |
2009年 | 17190篇 |
2008年 | 28157篇 |
2007年 | 30158篇 |
2006年 | 8819篇 |
2005年 | 10033篇 |
2004年 | 10373篇 |
2003年 | 10407篇 |
2002年 | 7768篇 |
2001年 | 4626篇 |
2000年 | 4416篇 |
1999年 | 3411篇 |
1998年 | 1499篇 |
1997年 | 1184篇 |
1996年 | 1031篇 |
1995年 | 956篇 |
1994年 | 842篇 |
1993年 | 697篇 |
1992年 | 1606篇 |
1991年 | 1648篇 |
1990年 | 1473篇 |
1989年 | 1309篇 |
1988年 | 1204篇 |
1987年 | 1067篇 |
1986年 | 1031篇 |
1985年 | 910篇 |
1984年 | 662篇 |
1983年 | 583篇 |
1982年 | 423篇 |
1981年 | 377篇 |
1980年 | 377篇 |
1979年 | 521篇 |
1978年 | 414篇 |
1977年 | 391篇 |
1976年 | 350篇 |
1974年 | 377篇 |
1973年 | 328篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
11.
Nikki Lee 《Journal of human lactation》2006,22(1):11; author reply 11-11; author reply 12
12.
H J Kim C H Kang Y T Kim S-W Sung J H Kim S M Lee C-G Yoo C-T Lee Y W Kim S K Han Y-S Shim J-J Yim 《The European respiratory journal》2006,28(3):576-580
Although surgical lung resection could improve prognosis in some patients with multidrug-resistant tuberculosis (MDR-TB), there are no reports on the optimal candidates for this surgery. The aim of the present study was to elucidate the prognostic factors for surgery in patients with MDR-TB. Patients who underwent lung resection for the treatment of MDR-TB between March 1993 and December 2004 were included in the present study. Treatment failure was defined as greater than or equal to two of the five cultures recorded in the final 12 months of treatment being positive, any one of the final three cultures being positive, or the patient having died during treatment. The variables that affected treatment outcomes were identified through univariate and multivariate logistic regression analysis. In total, 79 patients with MDR-TB were included in the present study. The treatment outcomes of 22 (27.8%) patients were classified as failure. A body mass index <18.5 kg x m(-2), primary resistance, resistance to ofloxacin and the presence of a cavitary lesion beyond the range of the surgical resection were associated with treatment failure. Low body mass index, primary resistance, resistance to ofloxacin and cavitary lesions beyond the range of resection are possible poor prognostic factors for surgical lung resection in multidrug-resistant tuberculosis patients. 相似文献
13.
14.
15.
Sung Woo Lee Sung Hyuk Choi Yunsik Hong Wanbae Kim 《European journal of emergency medicine》2006,13(2):117-118
Generally, a computed tomography scan is conducted for the diagnosis of stroke in the emergency department, because these scans are easier and faster in the detection of stroke. If there are no signs of hemorrhage on computed tomography scan, an ischemic stroke is diagnosed and treated accordingly. A magnetic resonance imaging scan may be taken in order to verify ischemic stroke. This process may lead to improper treatment and is time consuming. To address this situation, case studies are presented in which magnetic resonance imaging diffusion-weighted imaging and gradient recalled echo were performed to detect hemorrhagic and ischemic stroke and particularly, subarachnoid hemorrhage, which is undetectable with a computed tomography scan. 相似文献
16.
17.
18.
19.
Targeted silencing of disease-associated genes by synthetic short interfering RNA (siRNA) holds considerable promise as a novel therapeutic strategy. However, unmodified siRNA can be potent triggers of the innate immune response, particularly when associated with delivery vehicles that facilitate intracellular uptake. This represents a significant barrier to the therapeutic development of siRNA due to toxicity and off-target gene effects associated with this inflammatory response. Here we show that immune stimulation by synthetic siRNA can be completely abrogated by selective incorporation of 2'-O-methyl (2'OMe) uridine or guanosine nucleosides into one strand of the siRNA duplex. These noninflammatory siRNA, containing less than 20% modified nucleotides, can be readily generated without disrupting their gene-silencing activity. We show that, coupled with an effective systemic delivery vehicle, 2'OMe-modified siRNA targeting apolipoprotein B (apoB) can mediate potent silencing of its target mRNA, causing significant decreases in serum apoB and cholesterol. This is achieved at therapeutically viable siRNA doses without cytokine induction, toxicity, or off-target effects associated with the use of unmodified siRNA. This approach to siRNA design and delivery should prove widely applicable and represents an important step in advancing synthetic siRNA into a broad range of therapeutic areas. 相似文献
20.
Susanne Ramsauer 《Zeitschrift für Psychodrama und Soziometrie》2007,6(2):293-302
Anliegen dieses Artikels ist, die besondere Qualit?t und Chance von Psychodramatischer Supervision zu beschreiben, und gleichzeitig
die Kompatibilit?t und fruchtbare Erg?nzung des Moreno’schen Ansatzes innerhalb des Formats Supervision innerhalb der Sozialen
Arbeit auf zuzeigen. Dies wird anhand von 2 ausgew?hlten Praxisbeispielen dargestellt. Die Handlungskompetenz von Supervisandinnen
und Supervisanden kann durch einfache psychodramatische Interventionen erweitert werden. Handlungshemmung wird überwunden,
Spontaneit?t und Kreativit?t kommen ins Laufen und er?ffnen Perspektiven. 相似文献